Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Ted S. Strom"'
Autor:
Ted S Strom
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e55087 (2013)
Unlike anemias, most thrombocytopenias cannot be separated into those due to impaired production and those due to accelerated consumption. While rapid clearance of labeled platelets from the bloodstream can be followed in thrombocytopenic individuals
Externí odkaz:
https://doaj.org/article/2896202e9b4b40f6a7da30f72dd0b177
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e26657 (2011)
The study of ex vivo phagocytosis via flow cytometry requires that one distinguish experimentally between uptake and adsorption of fluorescently labeled targets by phagocytes. Removal of the latter quantity from the analysis is the most common means
Externí odkaz:
https://doaj.org/article/30aa0c18316444d0ba12c24105669f42
Autor:
Siham Boukour, Ted S. Strom, Gregory A. Voth, Najet Debili, Francisco X. Vázquez, Lining Ju, David R. Myers, Jorie Aardema, Hilary Christensen, Arinola Awomolo, Cheng Zhu, Seth J. Corey, Wilbur A. Lam, Reginald Tran, Yolande Chen, David J. Rawlings, Sayali Kale, Walter H. A. Kahr, David Reece, Elisabeth G. Blanchard, Zakary L. Whichard, Brian Chang
Publikováno v:
Blood. 122:1695-1706
Megakaryocytes generate platelets through extensive reorganization of the cytoskeleton and plasma membrane. Cdc42 interacting protein 4 (CIP4) is an F-BAR protein that localizes to membrane phospholipids through its BAR domain and interacts with Wisk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e05d710be216cba513fe41c3d2476fa2
https://doi.org/10.1182/blood-2013-03-484550
https://doi.org/10.1182/blood-2013-03-484550
Autor:
Pamela L. Schwartzberg, Masaki Shimizu, Fabio Candotti, Richard M. Siegel, Ted S. Strom, Daniel Bailey, Sophia Y. Cleland, Joseph Aoki, Nikolay P. Nikolov
Publikováno v:
Blood. 116:740-747
Autoimmunity is a surprisingly common complication of primary immunodeficiencies, yet the molecular mechanisms underlying this clinical observation are not well understood. One widely known example is provided by Wiskott-Aldrich syndrome (WAS), an X-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3631fa45737c52084fac9ea1f9f5fdcf
https://doi.org/10.1182/blood-2009-08-237560
https://doi.org/10.1182/blood-2009-08-237560
Autor:
Ted S. Strom
Publikováno v:
Immunologic Research. 44:42-53
In the first report of the concurrent immunodeficiency, thrombocytopenia, and eczema that we now call the Wiskott-Aldrich Syndrome (WAS), Alfred Wiskott asked whether it could be a familial form of Werlhof's disease (now called ITP). This review summ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b91fe678b9f7144a90fdb69353a7c98a
https://doi.org/10.1007/s12026-008-8069-2
https://doi.org/10.1007/s12026-008-8069-2
Autor:
Ted S. Strom, Carl W. Jackson, Alyssa L. Bolen, Bindumadhav M. Marathe, Falk Nimmerjahn, Amanda Prislovsky, Amira Hosni, Darryl Weiman
Publikováno v:
Experimental Hematology. 36:609-623
Objective Our objective was to determine a mechanism for the thrombocytopenia of murine Wiskott-Aldrich syndrome (WAS). Materials and Methods Consumption rates of WAS protein (WASP)(−) and wild-type (WT) platelets were measured by injection of 5-ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25b09f622c2bbe2592514c7d1cf8fa10
https://doi.org/10.1016/j.exphem.2007.12.019
https://doi.org/10.1016/j.exphem.2007.12.019
Autor:
Ted S. Strom, Stephen J. Turner, Haiyan Liu, Peter C. Doherty, Samita Andreansky, Arthur W. Nienhuis, John M. Cunningham, Deo Kumar Srivastava
Publikováno v:
Blood. 102:3108-3116
The Wiskott-Aldrich syndrome (WAS) is an X-linked disorder characterized by immune dysfunction, thrombocytopenia, and eczema. We used a murine model created by knockout of the WAS protein gene (WASP) to evaluate the potential of gene therapy for WAS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3228e75308ce9b8f5b98599164493859
https://doi.org/10.1182/blood-2002-11-3489
https://doi.org/10.1182/blood-2002-11-3489
Publikováno v:
Gene Therapy. 10:803-809
T-cell dysfunction is thought to be central to the immunodeficiency state seen in patients with the Wiskott-Aldrich syndrome (WAS). Aspects of the WAS phenotype have been corrected in other cell types on introduction of the normal WAS protein (WASP),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc57e18fee6b3af85c42302a27d9fb73
https://doi.org/10.1038/sj.gt.3301950
https://doi.org/10.1038/sj.gt.3301950
Publikováno v:
Blood. 100:3361-3368
Homeostasis of the extracellular matrix is a delicate balance between degradation and remodeling, the balance being maintained by the interaction of activated matrix metalloproteinases (MMPs) and specific tissue inhibitors of matrix metalloproteinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6abe38969b8d3f026fb91d1162bee86
https://doi.org/10.1182/blood.v100.9.3361
https://doi.org/10.1182/blood.v100.9.3361
Autor:
Amanda Prislovsky, Ted S. Strom
Thrombocytopenia caused by rapid platelet consumption contributes to the severe thrombocytopenia of Wiskott-Aldrich syndrome (WAS) and to the milder thrombocytopenia seen in murine WAS. We show that rapid clearance of ¹¹¹In-labeled murine WASP(-)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7818b0399919073f6ff799a73a784bdb
https://europepmc.org/articles/PMC3884558/
https://europepmc.org/articles/PMC3884558/
