Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ted S G A M, van den Ingh"'
Autor:
Hille Fieten, Yadvinder Gill, Alan J. Martin, Mafalda Concilli, Karen Dirksen, Frank G. van Steenbeek, Bart Spee, Ted S. G. A. M. van den Ingh, Ellen C. C. P. Martens, Paola Festa, Giancarlo Chesi, Bart van de Sluis, Roderick H. J. H. Houwen, Adrian L. Watson, Yurii S. Aulchenko, Victoria L. Hodgkinson, Sha Zhu, Michael J. Petris, Roman S. Polishchuk, Peter A. J. Leegwater, Jan Rothuizen
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 1, Pp 25-38 (2016)
The deleterious effects of a disrupted copper metabolism are illustrated by hereditary diseases caused by mutations in the genes coding for the copper transporters ATP7A and ATP7B. Menkes disease, involving ATP7A, is a fatal neurodegenerative disorde
Externí odkaz:
https://doaj.org/article/ed1cab5637da4a468e9d141775e641c2
Autor:
Karen Dirksen, Bart Spee, Louis C Penning, Ted S G A M van den Ingh, Iwan A Burgener, Adrian L Watson, Marian Groot Koerkamp, Jan Rothuizen, Frank G van Steenbeek, Hille Fieten
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0176826 (2017)
Copper is an essential trace element, but can become toxic when present in abundance. The severe effects of copper-metabolism imbalance are illustrated by the inherited disorders Wilson disease and Menkes disease. The Labrador retriever dog breed is
Externí odkaz:
https://doaj.org/article/155dbf7dcdcf4302b3c3d9be1711c65e
Autor:
Robert P Favier, Bart Spee, Baukje A Schotanus, Ted S G A M van den Ingh, Hille Fieten, Bas Brinkhof, Cornelia S Viebahn, Louis C Penning, Jan Rothuizen
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42158 (2012)
New therapeutic concepts developed in rodent models should ideally be evaluated in large animal models prior to human clinical application. COMMD1-deficiency in dogs leads to hepatic copper accumulation and chronic hepatitis representing a Wilson's d
Externí odkaz:
https://doaj.org/article/f49d5446f4a84dbf85d28891ba855bc2
Publikováno v:
Journal of Veterinary Internal Medicine. 20:1085-1092
Inherited defects of copper metabolism resulting in hepatic copper accumulation and oxidative-stress might cause breed-associated forms of hepatitis. Biliary excretion is the major elimination route of copper, therefore increased hepatic copper conce
Autor:
Martin Heinrichs, Lisette Jansen in de Wal, Rob C J Stooker, Ted S G A M van den Ingh, Johan D van Amerongen, Johannes H. van der Kolk
Publikováno v:
American Journal of Veterinary Research. 65:1701-1707
Objective—To determine size and weight of the pituitary gland and associations between pituitary gland size and weight and sex and age in horses without clinical signs associated with pituitary pars intermedia adenoma (PPIA) and horses and ponies w
Autor:
Hedwig S, Kruitwagen, Brigitte, Arends, Bart, Spee, Bas, Brinkhof, Ted S G A M, van den Ingh, Victor P M G, Rutten, Louis C, Penning, Tania, Roskams, Jan, Rothuizen
Publikováno v:
Liver international : official journal of the International Association for the Study of the Liver. 31(7)
Although the liver has a large regenerative capacity, in many hepatopathies, these repair mechanisms fail. The therapeutic potential of hepatocyte growth factor (HGF) has been proven in numerous toxin-induced liver failure models in rodents, but neve
Publikováno v:
Journal of veterinary internal medicine. 19(2)
Autor:
Joris H, Robben, Yvonne W E A, Pollak, Jolle, Kirpensteijn, Susanne A E B, Boroffka, Ted S G A M, van den Ingh, Erik, Teske, George, Voorhout
Publikováno v:
Journal of veterinary internal medicine. 19(1)
Accurate preoperative detection, localization, and staging of the primary tumor and metastases are essential for the selection of appropriate candidates for surgery. In dogs with insulinoma, preoperative assessment usually is performed with transabdo