Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Ted S Acott"'
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0122483 (2015)
Elevated intraocular pressure (IOP) is the primary risk factor for glaucoma, and lowering IOP remains the only effective treatment for glaucoma. The trabecular meshwork (TM) in the anterior chamber of the eye regulates IOP by generating resistance to
Externí odkaz:
https://doaj.org/article/68f31872feb74528acc989570cc48698
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48523 (2012)
Hyaluronan (HA) is a major component of the extracellular matrix (ECM) and is synthesized by three HA synthases (HAS). Similarities between the HAS2 knockout mouse and the hdf mutant mouse, which has a mutation in the versican gene, suggest that HA a
Externí odkaz:
https://doaj.org/article/033b46c351d04690913efd0f4bf86015
Publikováno v:
Bioengineering, Vol 10, Iss 9, p 1038 (2023)
Background: More than ~70% of the aqueous humor exits the eye through the conventional aqueous outflow pathway that is comprised of the trabecular meshwork (TM), juxtacanalicular tissue (JCT), the inner wall endothelium of Schlemm’s canal (SC). The
Externí odkaz:
https://doaj.org/article/23889279e6ca45e19cedeb8871b4a89e
Autor:
Alireza Karimi, Shanjida Khan, Reza Razaghi, Seyed Mohammadali Rahmati, Michael Gathara, Erika Tudisco, Mini Aga, Mary J. Kelley, Yifan Jian, Ted S. Acott
Publikováno v:
Acta Biomaterialia. 164:346-362
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8fdd602c30e99ee743ba68e6eb4b005
https://doi.org/10.1016/j.actbio.2023.04.008
https://doi.org/10.1016/j.actbio.2023.04.008
Autor:
Alireza Karimi, Mahdi Halabian, Reza Razaghi, J. Crawford Downs, Mary J. Kelley, Ted S. Acott
Publikováno v:
Cells, Vol 11, Iss 23, p 3925 (2022)
A layer of proteoglycans and glycoproteins known as glycocalyx covers the surface of the trabecular meshwork (TM), juxtacanalicular tissue (JCT), and Schlemm’s canal (SC) inner wall of the conventional aqueous outflow pathway in the eye. This has b
Externí odkaz:
https://doaj.org/article/0a4fc3dea1294b04aec0c1b349dea016
Autor:
Alireza Karimi, Reza Razaghi, Seyed Mohammadali Rahmati, J. Crawford Downs, Ted S. Acott, Mary J. Kelley, Ruikang K. Wang, Murray Johnstone
Publikováno v:
Bioengineering, Vol 9, Iss 11, p 672 (2022)
Background: Aqueous humor outflow resistance in the trabecular meshwork (TM), juxtacanalicular connective tissue (JCT), and Schlemm’s canal (SC) endothelium of the conventional outflow pathway actively contribute to intraocular pressure (IOP) regul
Externí odkaz:
https://doaj.org/article/086c1b2f973941c691d204e632894c3c
Autor:
Alireza Karimi, Reza Razaghi, Steven Padilla, Seyed Mohammadali Rahmati, J. Crawford Downs, Ted S. Acott, Mary J. Kelley, Ruikang K. Wang, Murray Johnstone
Publikováno v:
Journal of Clinical Medicine; Volume 11; Issue 20; Pages: 6049
Background: Although the tissues comprising the ocular conventional outflow pathway have shown strong viscoelastic mechanical response to aqueous humor pressure dynamics, the viscoelastic mechanical properties of the trabecular meshwork (TM), juxtaca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f68c3ac394501ba3a587f750f4323ba
https://pubmed.ncbi.nlm.nih.gov/36294371
https://pubmed.ncbi.nlm.nih.gov/36294371
Autor:
Alireza Karimi, Devon J. Crouch, Reza Razaghi, J. Crawford Downs, Ted S. Acott, Mary J. Kelley, Julia G. Behnsen, Lucy A. Bosworth, Carl M. Sheridan
Publikováno v:
Computer Methods and Programs in Biomedicine. 236:107485
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1aec308b7c18aa3dfee70098b67398fb
https://doi.org/10.1016/j.cmpb.2023.107485
https://doi.org/10.1016/j.cmpb.2023.107485
Autor:
Jose M. Gonzalez, Ted S. Acott, W. Daniel Stamer, James C. Tan, Shravan K. Chintala, Tatsuo Itakura, Yuchen Wang, Andrew Webster, Cheryl M. Craft, M. Elizabeth Fini, Shinwu Jeong, Janice A. Vranka, Kirill A. Martemyanov, Maria Sibug Saber
Publikováno v:
J Ocul Pharmacol Ther
Purpose: GPR158 is a newly characterized family C G-protein-coupled receptor, previously identified in functional screens linked with biological stress, including one for susceptibility to ocular hypertension/glaucoma induced by glucocorticoid stress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::954c7801002d2c3084e30bb7f6bd3b09
https://doi.org/10.1089/jop.2018.0135
https://doi.org/10.1089/jop.2018.0135
Autor:
Alireza Karimi, Reza Razaghi, Seyed Mohammadali Rahmati, J. Crawford Downs, Ted S. Acott, Ruikang K. Wang, Murray Johnstone
Publikováno v:
Computer Methods and Programs in Biomedicine. 221:106922
Intraocular pressure (IOP) is determined by aqueous humor outflow resistance, which is a function of the combined resistance of Schlemm's canal (SC) endothelium and the trabecular meshwork (TM) and their interactions in the juxtacanalicular connectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d919243190269d1f0b542a761093281
https://doi.org/10.1016/j.cmpb.2022.106922
https://doi.org/10.1016/j.cmpb.2022.106922