Zobrazeno 1 - 10
of 401
pro vyhledávání: '"Ted R. Mikuls"'
Autor:
Emily E. Holladay, Amy S. Mudano, Fenglong Xie, Jingyi Zhang, Ted R. Mikuls, Brian LaMoreaux, Lissa Padnick-Silver, Jeffrey R. Curtis
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-11 (2024)
Abstract Background/Purpose Little is known about long-term clinical outcomes or urate-lowering (ULT) therapy use following pegloticase discontinuation. We examined ULT use, serum urate (SU), inflammatory biomarkers, and renal function following pegl
Externí odkaz:
https://doaj.org/article/dacf2495b86f436fb4c85b5bbe55702e
Autor:
Aaron D. Schwab, Todd A. Wyatt, Grace Moravec, Geoffrey M. Thiele, Amy J. Nelson, Angela Gleason, Oliver Schanze, Michael J. Duryee, Debra J. Romberger, Ted R. Mikuls, Jill A. Poole
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-16 (2024)
Abstract Background Environmental/occupational exposures cause significant lung diseases. Agricultural organic dust extracts (ODE) and bacterial component lipopolysaccharide (LPS) induce recruited, transitioning murine lung monocytes/macrophages, yet
Externí odkaz:
https://doaj.org/article/679f8daa696f4b38867233ba2722837f
Autor:
Stephanie Jeong, Michael D. George, Ted R. Mikuls, Bryant R. England, Brian Sauer, Grant W. Cannon, Joshua F. Baker
Publikováno v:
ACR Open Rheumatology, Vol 5, Iss 10, Pp 563-567 (2023)
Objective To determine whether prescribing practices for Janus kinase inhibitors (JAKi), tumor necrosis factor inhibitors (TNFi), and non‐TNFi biologic agents changed after the results of the Oral Rheumatoid Arthritis Trial (ORAL) Surveillance tria
Externí odkaz:
https://doaj.org/article/d20b4d599fdd44c4bc4bb628e0b9d5d7
Autor:
Beth I. Wallace, Bryant R. England, Joshua F. Baker, Jorge Rojas, Brian C. Sauer, Punyasha Roul, Gary A. Kunkel, Tawnie J. Braaten, Alison Petro, Ted R. Mikuls, Grant W. Cannon
Publikováno v:
ACR Open Rheumatology, Vol 5, Iss 9, Pp 437-442 (2023)
Objective In the Steroid EliMination In Rheumatoid Arthritis (SEMIRA) trial, 65% of patients with rheumatoid arthritis (RA) in low disease activity (LDA) on stable biologic therapy successfully tapered glucocorticoids. We aimed to evaluate real‐wor
Externí odkaz:
https://doaj.org/article/e0edea0a844943d58fe12d3f47edc1a0
Autor:
Daniel Van Kalsbeek, Rebecca Brooks, Dawson Shaver, Ariadne Ebel, Daniel Hershberger, Cynthia Schmidt, Jill A. Poole, Dana P. Ascherman, Geoffrey M. Thiele, Ted R. Mikuls, Bryant R. England
Publikováno v:
ACR Open Rheumatology, Vol 5, Iss 4, Pp 201-226 (2023)
Background Biomarkers have been proposed as tools to aid in the identification and prognostication of interstitial lung disease (ILD) in rheumatoid arthritis (RA). We performed a systematic review of studies evaluating peripheral blood biomarkers and
Externí odkaz:
https://doaj.org/article/378f6499d6a34a70b8dda937b0741f16
Autor:
George A. Karpouzas, Zoltán Szekanecz, Eva Baecklund, Ted R. Mikuls, Deepak L. Bhatt, Cunshan Wang, Gosford A. Sawyerr, Yan Chen, Sujatha Menon, Carol A. Connell, Steven R. Ytterberg, Mahta Mortezavi
Publikováno v:
Therapeutic Advances in Musculoskeletal Disease, Vol 15 (2023)
Background: In patients with rheumatoid arthritis (RA), persistent inflammation and increasing disease activity are associated with increased risk of adverse events (AEs). Objectives: To assess relationships between RA disease activity and AEs of int
Externí odkaz:
https://doaj.org/article/87609669a463447b9ca9297342cee922
Autor:
Nozima Aripova, Michael J. Duryee, Bryant R. England, Carlos D. Hunter, Jack E. Mordeson, Evan M. Ryan, Eric C. Daubach, Debra J. Romberger, Geoffrey M. Thiele, Ted R. Mikuls
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
ObjectivePost-translational protein modifications with malondialdehyde-acetaldehyde (MAA) and citrulline (CIT) are implicated in the pathogenesis of rheumatoid arthritis (RA). Although precise mechanisms have not been elucidated, macrophage-fibroblas
Externí odkaz:
https://doaj.org/article/0365c73536f742548053bf03c1ff0bcc
Autor:
Monica Guma, Benyamin Dadpey, Roxana Coras, Ted R. Mikuls, Bartlett Hamilton, Oswald Quehenberger, Hilda Thorisdottir, David Bittleman, Kimberly Lauro, Shannon M. Reilly, Ru Liu-Bryan, Robert Terkeltaub
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-13 (2022)
Abstract Objective Linked metabolic and cardiovascular comorbidities are prevalent in hyperuricemia and gout. For mechanistic insight into impact on inflammatory processes and cardiometabolic risk factors of xanthine oxidase inhibitor urate-lowering
Externí odkaz:
https://doaj.org/article/2e001f3b06a94a069b0f462242812c21
Autor:
Hannah E. Lomzenski, Geoffrey M. Thiele, Michael J. Duryee, Sheau-Chiann Chen, Fei Ye, Daniel R. Anderson, Ted R. Mikuls, Michelle J. Ormseth
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Patients with rheumatoid arthritis (RA) have increased atherosclerosis; oxidative stress may be a contributor. Oxidative stress produces immunogenic malondialdehyde-acetaldehyde (MAA) protein adducts and anti-MAA antibodies are detectable in
Externí odkaz:
https://doaj.org/article/d574f9ba36ab47a2a9f75bf1ebfd611c
Autor:
Jill A. Poole, Ted R. Mikuls, Geoffrey M. Thiele, Rohit Gaurav, Amy J. Nelson, Michael J. Duryee, Ananya Mitra, Carlos Hunter, Todd A. Wyatt, Bryant R. England, Dana P. Ascherman
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-15 (2022)
Abstract Immunogenetic as well as environmental and occupational exposures have been linked to the development of rheumatoid arthritis (RA), RA-associated lung disease, and other primary lung disorders. Importantly, various inhalants can trigger post
Externí odkaz:
https://doaj.org/article/6715afcf5ca64ddfa7c719475c176126