Novel FFPE proteomics method suggests prolactin induced protein as hormone induced cytoskeleton remodeling spatial biomarker

Autor: Jakub Faktor, Sachin Kote, Michal Bienkowski, Ted R. Hupp, Natalia Marek-Trzonkowska

Publikováno v: Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)

Abstract Robotically assisted proteomics provides insights into the regulation of multiple proteins achieving excellent spatial resolution. However, developing an effective method for spatially resolved quantitative proteomics of formalin fixed paraf

Externí odkaz: https://doaj.org/article/e1837fd34ef04a03affab9584bfa194a

CHIP-dependent regulation of the actin cytoskeleton is linked to neuronal cell membrane integrity

Autor: Catarina Dias, Erisa Nita, Jakub Faktor, Ailish C. Tynan, Lenka Hernychova, Borivoj Vojtesek, Jesper Nylandsted, Ted R. Hupp, Tilo Kunath, Kathryn L. Ball

Publikováno v: iScience, Vol 25, Iss 3, Pp 103921- (2022)

Externí odkaz: https://doaj.org/article/184f2fb85b014d7dbde811a7e9b3a77b

Emergent Role of IFITM1/3 towards Splicing Factor (SRSF1) and Antigen-Presenting Molecule (HLA-B) in Cervical Cancer

Autor: Maria Gómez-Herranz, Jakub Faktor, Marcos Yébenes Mayordomo, Magdalena Pilch, Marta Nekulova, Lenka Hernychova, Kathryn L. Ball, Borivoj Vojtesek, Ted R. Hupp, Sachin Kote

Publikováno v: Biomolecules, Vol 12, Iss 8, p 1090 (2022)

The IFITM restriction factors play a role in cancer cell progression through undefined mechanisms. We investigate new protein–protein interactions for IFITM1/3 in the context of cancer that would shed some light on how IFITM1/3 attenuate the expres

Externí odkaz: https://doaj.org/article/f6ccedfb34244f7587bb5ef5265a4bb5

The immunopeptidome from a genomic perspective:Establishing the noncanonical landscape of MHC class I–associated peptides

Autor: Georges Bedran, Hans-Christof Gasser, Kenneth Weke, Tongjie Wang, Dominika Bedran, Alexander Laird, Christophe Battail, Fabio Massimo Zanzotto, Catia Pesquita, Håkan Axelson, Ajitha Rajan, David J. Harrison, Aleksander Palkowski, Maciej Pawlik, Maciej Parys, J. Robert O'Neill, Paul M. Brennan, Stefan N. Symeonides, David R. Goodlett, Kevin Litchfield, Robin Fahraeus, Ted R. Hupp, Sachin Kote, Javier A. Alfaro

Publikováno v: Bedran, G, Gasser, H-C, Weke, K, Wang, T, Bedran, D, Laird, A, Battail, C, Zanzotto, F M, Pesquita, C, Axelson, H, Rajan, A, Harrison, D J, Palkowski, A, Pawlik, M, Parys, M, O'Neill, J R, Brennan, P M, Symeonides, S N, Goodlett, D R, Litchfield, K, Fahraeus, R, Hupp, T R, Kote, S & Alfaro, J A 2023, ' The immunopeptidome from a genomic perspective : Establishing the noncanonical landscape of MHC class I–associated peptides ', Cancer Immunology Research, vol. 11, no. 6, 22-0621, pp. 747-762 . https://doi.org/10.1158/2326-6066.CIR-22-0621

G.B., D.B., K.W., A.P., R.F., T.R.H., S.K., and J.A.A. received support from Fundacja na rzecz Nauki Polskiej (FNP) (grant ID: MAB/3/2017). D.R.G. received support from Genome Canada & Genome BC (grant ID: 264PRO). D.J.H. received support from NuCana

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5640b6d17b1b5d9d901c149d1c8f822
https://hdl.handle.net/20.500.11820/79dfea72-bb92-4676-9d56-b1ba634e38e9

Supplementary Table 3 from The Immunopeptidome from a Genomic Perspective: Establishing the Noncanonical Landscape of MHC Class I–Associated Peptides

Autor: Javier A. Alfaro, Sachin Kote, Ted R. Hupp, Robin Fahraeus, Kevin Litchfield, David R. Goodlett, Stefan N. Symeonides, Paul M. Brennan, J. Robert O'Neill, Maciej Parys, Maciej Pawlik, Aleksander Palkowski, David J. Harrison, Ajitha Rajan, Håkan Axelson, Catia Pesquita, Fabio Massimo Zanzotto, Christophe Battail, Alexander Laird, Dominika Bedran, Tongjie Wang, Kenneth Weke, Hans-Christof Gasser, Georges Bedran

Annotation of the COD-dipp ncMAPs.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af2e44ead80dd72875f02192da799d77
https://doi.org/10.1158/2326-6066.22732017