Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Ted Johanson"'
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Introduction:Escherichia coli, a well characterized workhorse in biotechnology, has been used to produce many recombinant proteins and metabolites, but have a major drawback in its tendency to revert to overflow metabolism. This phenomenon occurs whe
Externí odkaz:
https://doaj.org/article/045664ff78844d5caa4db1d72bcec866
Publikováno v:
Microorganisms, Vol 10, Iss 6, p 1145 (2022)
Large-scale microbial industrial fermentations have significantly higher absolute pressure and dissolved CO2 concentrations than otherwise comparable laboratory-scale processes. Yet the effect of increased dissolved CO2 (dCO2) levels is rarely addres
Externí odkaz:
https://doaj.org/article/f3aa4bfd99df427d8e4d0b54830d8612
Autor:
Anna-Lena Heins, Ted Johanson, Shanshan Han, Luisa Lundin, Magnus Carlquist, Krist V. Gernaey, Søren J. Sørensen, Anna Eliasson Lantz
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 7 (2019)
Microbial cells in bioprocesses are usually described with averaged parameters. But in fact, single cells within populations vary greatly in characteristics such as stress resistance, especially in response to carbon source gradients. Our aim was to
Externí odkaz:
https://doaj.org/article/77623e11a0a746b8adf2c497d76d7a4a
Publikováno v:
Biotechnology Reports, Vol 7, Iss C, Pp 107-119 (2015)
A control point for keeping redox homeostasis in Saccharomyces cerevisiae during fermentative growth is the dynamic regulation of transcription for the glycerol-3-phosphate dehydrogenase 2 (GPD2) gene. In this study, the possibility to steer the acti
Externí odkaz:
https://doaj.org/article/6d09766fc52e4ba8b3ee3a7a0e652b5b
Autor:
Katrine Bych, Louise Kristine Vigsnæs, Marta H. Mikš, Ted Johanson, Peter Becker, Markus Jondelius Hederos
Publikováno v:
Current Opinion in Biotechnology. 56:130-137
Human Milk Oligosaccharides (HMOs) constitute an important, highly abundant part of mothers' milk delivering many health benefits to the neonate. Until recently, limited availability of HMOs has prevented their use in infant nutrition and impeded res
Autor:
Annick Lejeune, Samuel Telek, Jonathan Baert, Anna Eliasson Lantz, Frank Delvigne, Ted Johanson, Sébastien Gofflot
Publikováno v:
Journal of Chemical Technology & Biotechnology. 90:314-323
BACKGROUND Single cell biology has attracted a lot of attention in recent years and has led to numerous fundamental results pointing out the heterogeneity of clonal cell populations. In this context, microbial phenotypic heterogeneity under bioproces
Publikováno v:
FEMS Yeast Research. 5:513-525
Pure chiral molecules are needed in the pharmaceutical and chemical industry as intermediates for the production of drugs or fine chemicals. Microorganisms represent an attractive alternative to chemical synthesis since they have the potential to gen
Publikováno v:
Schalén, M, Johanson, T, Lundin, L, Sørensen, S & Eliasson Lantz, A 2012, ' Heterogeneity in recombinant protein production ', New Biotechnology, vol. 29S, pp. S78 . https://doi.org/10.1016/j.nbt.2012.08.217
A crucial step in biotechnology is the scale-up process. Normally, lab scale verification and optimization of production processes and strains are performed in small reactors with perfect mixing andhence the cells experience a homogenous environment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0615cd7e58752b62d6c76ebe39971da
https://orbit.dtu.dk/en/publications/fe7bde36-a8fd-41fd-a5e3-96a71d5a2135
https://orbit.dtu.dk/en/publications/fe7bde36-a8fd-41fd-a5e3-96a71d5a2135
Autor:
Arto Heiskanen, Tautgirdas Ruzgas, Marie F. Gorwa-Grauslund, Milena Koudelka-Hep, Natalie Kostesha, Jenny Emnéus, Christer Spegel, Ted Johanson
Publikováno v:
Analytical chemistry. 79(23)
The two main metabolic pathways involved in sugar metabolism, i.e., the pentose phosphate pathway (PPP) and the glycolytic pathway (GP), were amperometrically monitored using a double-mediator system composed of menadione and ferricyanide. With the u
Autor:
Torbjörn Frejd, Ted Johanson, Marie-Francoise Gorwa-Grauslund, Magnus Carlquist, Cecilia Olsson, Andreas Rudolf
Publikováno v:
Applied microbiology and biotechnology. 77(5)
Reduction of bicyclo[2.2.2]octane-2,6-dione to (1R, 4S, 6S)-6-hydroxy-bicyclo[2.2.2]octane-2-one by whole cells of Saccharomyces cerevisiae was improved using an engineered recombinant strain and process design. The substrate inhibition followed a Ha