Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ted C. Chu"'
Autor:
Matthew Levy, Andrew D. Ellington, Michael G. Rosenblum, Sarah Faulkner, Laura A. Lavery, John W. Marks, Ted C. Chu
Supplementary Figure 7 from Aptamer:Toxin Conjugates that Specifically Target Prostate Tumor Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3440992daebbfa84be62ae339a1e585
https://doi.org/10.1158/0008-5472.22365435.v1
https://doi.org/10.1158/0008-5472.22365435.v1
Autor:
Matthew Levy, Andrew D. Ellington, Michael G. Rosenblum, Sarah Faulkner, Laura A. Lavery, John W. Marks, Ted C. Chu
Supplementary Figures 1-6 from Aptamer:Toxin Conjugates that Specifically Target Prostate Tumor Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2085c2dace2c4d1e3a20c7c1c37d7daa
https://doi.org/10.1158/0008-5472.22365432
https://doi.org/10.1158/0008-5472.22365432
Autor:
Matthew Levy, Andrew D. Ellington, Michael G. Rosenblum, Sarah Faulkner, Laura A. Lavery, John W. Marks, Ted C. Chu
We have used RNA aptamer:gelonin conjugates to target and specifically destroy cells overexpressing the known cancer biomarker prostate-specific membrane antigen (PSMA). Aptamer:toxin conjugates have an IC50 of 27 nmol/L and display an increased pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b81f4bccc68bc12cb0ca27c9e1daba3
https://doi.org/10.1158/0008-5472.c.6494697.v1
https://doi.org/10.1158/0008-5472.c.6494697.v1
Autor:
Ted C. Chu, John W. Marks, Matthew Levy, Sarah Faulkner, Andrew D. Ellington, Laura A. Lavery, Michael G. Rosenblum
Publikováno v:
Cancer Research. 66:5989-5992
We have used RNA aptamer:gelonin conjugates to target and specifically destroy cells overexpressing the known cancer biomarker prostate-specific membrane antigen (PSMA). Aptamer:toxin conjugates have an IC50 of 27 nmol/L and display an increased pote
Autor:
Matthew Levy, Rebecca Richards-Kortum, Laura A. Lavery, Brian A. Korgel, Felice Shieh, Andrew D. Ellington, Ted C. Chu
Publikováno v:
Biosensors and Bioelectronics. 21:1859-1866
Aptamers that bind to prostate specific membrane antigen (PSMA) were conjugated to luminescent CdSe and CdTe nanocrystals for cell-labeling studies. The aptamer-nanocrystal conjugates showed specific targeting of both fixed and live cells that overex
Publikováno v:
Nucleic Acids Research
Nucleic acids that bind to cells and are subsequently internalized could prove to be novel delivery reagents. An anti-prostate specific membrane antigen aptamer that has previously been shown to bind to prostate tumor cells was coupled to siRNAs via