Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Technical aspects of cell biology"'
Autor:
Thomas Chow, William Humble, Enrico Lucarelli, Carmine Onofrillo, Peter F. Choong, Claudia Di Bella, Serena Duchi
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110251- (2024)
Summary: Osteosarcoma is a highly aggressive primary bone tumor that has seen little improvement in survival rates in the past three decades. Preclinical studies are conducted on a small pool of commercial cell lines which may not fully reflect the g
Externí odkaz:
https://doaj.org/article/43ddd9fb653b43e7a293ade9a7e87f9d
Autor:
Bernarda Majc, Anamarija Habič, Marta Malavolta, Miloš Vittori, Andrej Porčnik, Roman Bošnjak, Jernej Mlakar, Alenka Matjašič, Andrej Zupan, Marija Skoblar Vidmar, Tamara Lah Turnšek, Aleksander Sadikov, Barbara Breznik, Metka Novak
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110604- (2024)
Summary: Glioblastoma (GB) is the most common primary malignant brain tumor, characterized by resistance to therapy. Despite aggressive treatment options, GB remains an incurable disease. Invasiveness and heterogeneity are key GB features that cannot
Externí odkaz:
https://doaj.org/article/2811208931514fd98a2e14598552201e
Autor:
Sam G. Edalat, Reto Gerber, Miranda Houtman, Janine Lückgen, Rui Lourenço Teixeira, Maria del Pilar Palacios Cisneros, Tamara Pfanner, Tadeja Kuret, Nadja Ižanc, Raphael Micheroli, Joaquim Polido-Pereira, Fernando Saraiva, Swathi Lingam, Kristina Burki, Blaž Burja, Chantal Pauli, Žiga Rotar, Matija Tomšič, Saša Čučnik, João Eurico Fonseca, Oliver Distler, Ângelo Calado, Vasco C. Romão, Caroline Ospelt, Snežna Sodin-Semrl, Mark D. Robinson, Mojca Frank Bertoncelj
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109707- (2024)
Summary: In this study, we optimized the dissociation of synovial tissue biopsies for single-cell omics studies and created a single-cell atlas of human synovium in inflammatory arthritis. The optimized protocol allowed consistent isolation of highly
Externí odkaz:
https://doaj.org/article/4949afb345a94708b58cea17f6bb5dbc
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107941- (2023)
Summary: Individual cells exhibit substantial heterogeneity in protein abundance and activity, which is frequently reflected in broad distributions of fluorescently labeled reporters. Since all cellular components are intrinsically fluorescent to som
Externí odkaz:
https://doaj.org/article/787254043b0640209c15eb1036306db1
Akademický článek
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Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
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Autor:
Jon F. Edd, Avanish Mishra, Kyle C. Smith, Ravi Kapur, Shyamala Maheswaran, Daniel A. Haber, Mehmet Toner
Publikováno v:
iScience, Vol 25, Iss 8, Pp 104696- (2022)
Summary: Circulating tumor cells (CTCs) enter the vasculature from solid tumors and disseminate widely to initiate metastases. Mining the metastatic-enriched molecular signatures of CTCs before, during, and after treatment holds unique potential in p
Externí odkaz:
https://doaj.org/article/446f9c3da8774d009700741fdd78d777
Autor:
Shuyao Gu, Rachel M. Lee, Zackery Benson, Chenyi Ling, Michele I. Vitolo, Stuart S. Martin, Joe Chalfoun, Wolfgang Losert
Publikováno v:
iScience, Vol 25, Iss 7, Pp 104678- (2022)
Summary: Collective cell migration is an umbrella term for a rich variety of cell behaviors, whose distinct character is important for biological function, notably for cancer metastasis. One essential feature of collective behavior is the motion of c
Externí odkaz:
https://doaj.org/article/462a0c8916aa4a2695b173d8bca64579
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104275- (2022)
Summary: Cell mechanics is closely related to and interacts with cellular functions, which has the potential to be an effective biomarker to indicate disease onset and progression. Although several techniques have been developed for measuring cell me
Externí odkaz:
https://doaj.org/article/31c2d9c67e704c0ca1eb15b133a80f7b
Autor:
Yutaka Ogawa, Naoko Imamoto
Publikováno v:
iScience, Vol 24, Iss 12, Pp 103503- (2021)
Summary: To understand various intranuclear functions, it is important to know when, what, and how proteins enter the nucleus. Although many methods and commercial kits for nuclear fractionation have been developed, there are still no methods for obt
Externí odkaz:
https://doaj.org/article/a579f4e839e4418596da7f38a6eda6cf