Výsledky vyhledávání

Increased degradation of ATP is driven by memory~regulatory T cells in kidney transplantation tolerance

Autor: Carole Brosseau, Eugénie Durand, Magali Giral, Maxim Durand, Pierrick Guerif, Nathalie Bonnefoy, Florian Dubois, Jean-François Eliaou, Cécile Dejou, Nicolas Degauque, Sophie Brouard, Richard Danger, Jean-Paul Soulillou, Mélanie Chesneau

Publikováno v: Kidney International
Kidney International, Nature Publishing Group, 2018, 93 (5), pp.1154--1164. ⟨10.1016/j.kint.2017.12.004⟩
Kidney International, 2018, 93 (5), pp.1154--1164. ⟨10.1016/j.kint.2017.12.004⟩

Regulatory T cells were recently proposed as the central actor in operational tolerance after renal transplantation. Tolerant patients harbor increased FoxP3hi memory Treg frequency and increased demethylation in the Foxp3 Treg-specific demethylated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::928272b16fa6243be14e96b8579039f2
https://www.hal.inserm.fr/hal-01881134

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Regulation of the Immune Response by the Inflammatory Metabolic Microenvironment in the Context of Allotransplantation

Autor: Degauque, Nicolas, Brosseau, Carole, Brouard, Sophie

Publikováno v: Frontiers in Immunology
Frontiers in Immunology, 2018, 9, pp.1465. ⟨10.3389/fimmu.2018.01465⟩

International audience; Antigen challenge induced by allotransplantation results in the activation of T and B cells, followed by their differentiation and proliferation to mount an effective immune response. Metabolic fitness has been shown to be cru

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7b93b8f124a6c121cfc7e087717453f5
https://pubmed.ncbi.nlm.nih.gov/29988548

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Poor Patient and Graft Outcome After Induction Treatment by Antithymocyte Globulin in Recipients of a Kidney Graft After Nonrenal Organ Transplantation

Publikováno v: Transplantation direct, vol 4, iss 4
Transplantation Direct
Transplantation Direct, 2018, pp.1. ⟨10.1097/TXD.0000000000000772⟩
Transplantation Direct, Vol 4, Iss 4, p e357 (2018)
Transplantation Direct, Wolters Kluwer, 2018, pp.1. ⟨10.1097/TXD.0000000000000772⟩

Supplemental digital content is available in the text.
Background End-stage renal failure occurs in a substantial number of patients having received a nonrenal transplantation (NRT), for whom a kidney transplantation is needed. The medical strat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53059953891bb88415b042b07bf73b97
https://escholarship.org/uc/item/7mv9m7h7

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HCMV triggers frequent and persistent UL40- specific unconventional HLA-E-restricted CD8 T-cell responses with potential autologous and allogeneic peptide recognition

Autor: Jouand, Nicolas, Bressollette-Bodin, Céline, Gérard, Nathalie, Giral, Magali, Guérif, Pierrick, Rodallec, Audrey, Oger, Romain, Parrot, Tiphaine, Allard, Mathilde, Cesbron-Gautier, Anne, Gervois, Nadine, Charreau, Béatrice

Publikováno v: PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2018, 14 (4), pp.e1007041. 〈10.1371/journal.ppat.1007041〉
PLoS Pathogens, 2018, 14 (4), pp.e1007041. ⟨10.1371/journal.ppat.1007041⟩
PLoS Pathogens, Public Library of Science, 2018, 14 (4), pp.e1007041
PLoS Pathogens, Public Library of Science, 2018, 14 (4), pp.e1007041. ⟨10.1371/journal.ppat.1007041⟩
PLoS Pathogens, Vol 14, Iss 4, p e1007041 (2018)

Immune response against human cytomegalovirus (HCMV) includes a set of persistent cytotoxic NK and CD8 T cells devoted to eliminate infected cells and to prevent reactivation. CD8 T cells against HCMV antigens (pp65, IE1) presented by HLA class-I mol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::390d2f2ea0bf70cf1ee77f42b2adf86a
http://www.hal.inserm.fr/inserm-01812003/file/ppat.1007041_2018Eq3.pdf

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Vasculitides induced by cocaine and/or levamisole

Autor: Christian Agard, Antoine Néel, Mohamed Hamidou

Publikováno v: Joint Bone Spine
Joint Bone Spine, 2018, 85 (1), pp.9--14. ⟨10.1016/j.jbspin.2017.05.022⟩

International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6557ff57ccdee05cca0052fb85179b30
https://www.hal.inserm.fr/hal-01881143

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Renal cortical volume: High correlation with pre- and post-operative renal function in living kidney donors

Autor: Sophie Limou, Christophe Perret, Pierre-Antoine Gourraud, Pierre-Marie Heudes, Lola Jacquemont, Eric Frampas, Maryvonne Hourmant, Edouard Gardan

Publikováno v: European Journal of Radiology
European Journal of Radiology, 2018, 99, pp.118--123. ⟨10.1016/j.ejrad.2017.12.013⟩

Background CT volumetry has previously been proposed as an alternative to scintigraphy for the evaluation of pre-donation split renal function and the prediction of post-donation renal function in living kidney donors. The aim of our study was to ret

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c77d57e7e87247905f0f8d7fab980e86
https://www.hal.inserm.fr/hal-01881155

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MD1003 (High-Dose Pharmaceutical-Grade Biotin) for the Treatment of Chronic Visual Loss Related to Optic Neuritis in Multiple Sclerosis: A Randomized, Double-Blind, Placebo-Controlled Study

Publikováno v: CNS Drugs
CNS Drugs, Springer Verlag, 2018, 32 (7), pp.661--672. ⟨10.1007/s40263-018-0528-2⟩
CNS Drugs, 2018, 32 (7), pp.661-672
CNS Drugs, Springer Verlag, 2018, 32 (7), pp.661-672

Background Chronic visual loss is a disabling feature in patients with multiple sclerosis (MS). It was recently shown that MD1003 (high-dose pharmaceutical-grade biotin or hdPB) may improve disability in patients with progressive MS. Objective The ai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b54fc365bdbad949287a92b7979afdd1
https://www.hal.inserm.fr/inserm-02157957

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Notch signaling triggered via the ligand DLL4 impedes M2 macrophage differentiation and promotes their apoptosis

Autor: Nathalie Gérard, Béatrice Charreau, Sylvain Pagie

Publikováno v: Cell Communication and Signaling : CCS
Cell Communication and Signaling, Vol 16, Iss 1, Pp 1-12 (2018)
Cell Communication and Signaling
Cell Communication and Signaling, 2018, 16 (1), pp.958. ⟨10.1186/s12964-017-0214-x⟩

Background Notch signaling controls many cellular processes, including cell fate determination, cell differentiation, proliferation and apoptosis. In mammals, four Notch receptors (Notch 1–4) can interact with five distinct ligands [Jagged1, Jagged

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ac70af698fcffb83feac0b82faa1a9f
http://europepmc.org/articles/PMC5764024

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