Post-exposure Lopinavir-Ritonavir Prophylaxis versus Surveillance for Individuals Exposed to SARS-CoV-2: The COPEP Pragmatic Open-Label, Cluster Randomized Trial.

Autor: Labhardt ND; Department of Infectious Diseases and Hospital Epidemiology, University of Basel, Basel, Switzerland.; Department of Medicine, Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland., Smit M; Division of Infectious Diseases, Geneva University Hospitals, Faculty of Medicine, Geneva, Switzerland.; Department of Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland., Petignat I; Division of Infectious Diseases, Geneva University Hospitals, Faculty of Medicine, Geneva, Switzerland., Perneger T; Division of Clinical Epidemiology, Geneva University Hospitals, Geneva, Switzerland., Marinosci A; Division of Infectious Diseases, Geneva University Hospitals, Faculty of Medicine, Geneva, Switzerland., Ustero P; Division of Infectious Diseases, Geneva University Hospitals, Faculty of Medicine, Geneva, Switzerland., Diniz Ribeiro MP; Lab. De Pesquisa Clinica DST/AIDS, Instituto Nacional de Infectologia Evandro Chagas, Fiocruz, Rio de Janeiro, Brazil., Ragozzino S; Department of Infectious Diseases and Hospital Epidemiology, University of Basel, Basel, Switzerland., Nicoletti GJ; Department of Infectious Diseases and Hospital Epidemiology, University of Basel, Basel, Switzerland.; Department of Medicine, Swiss Tropical and Public Health Institute, Basel, Switzerland., Faré PB; Division of Infectious Diseases, Ospedale Regionale di Lugano and Faculty of Medicine, University of Southern Switzerland, Lugano, Switzerland., Andrey DO; Division of Infectious Diseases, Geneva University Hospitals, Faculty of Medicine, Geneva, Switzerland.; Division of Laboratory Medicine, Diagnostic Department, Geneva University Hospitals, Geneva, Switzerland., Jacquerioz F; Division and Department of Primary Care, Geneva University Hospitals, Geneva, Switzerland., Lebowitz D; Infection Control Program, Geneva University Hospitals, Geneva, Switzerland., Agoritsas T; Division of General Internal Medicine, Geneva University Hospital, Geneva, Switzerland.; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada., Meyer B; Centre for Vaccinology, Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland., Spechbach H; Division and Department of Primary Care, Geneva University Hospitals, Geneva, Switzerland., Salamun J; Division and Department of Primary Care, Geneva University Hospitals, Geneva, Switzerland., Guessous I; Division and Department of Primary Care, Geneva University Hospitals, Geneva, Switzerland., Chappuis F; Division and Department of Primary Care, Geneva University Hospitals, Geneva, Switzerland., Kaiser L; Division of Infectious Diseases, Geneva University Hospitals, Faculty of Medicine, Geneva, Switzerland.; Geneva Centre for Emerging Viral Diseases, Geneva University Hospitals, Geneva, Switzerland., Decosterd LA; Laboratory of Clinical Pharmacology, University of Lausanne, Lausanne, Switzerland., Grinsztejn B; Lab. De Pesquisa Clinica DST/AIDS, Instituto Nacional de Infectologia Evandro Chagas, Fiocruz, Rio de Janeiro, Brazil., Bernasconi E; Division of Infectious Diseases, Ospedale Regionale di Lugano and Faculty of Medicine, University of Southern Switzerland, Lugano, Switzerland., Cardoso SW; Lab. De Pesquisa Clinica DST/AIDS, Instituto Nacional de Infectologia Evandro Chagas, Fiocruz, Rio de Janeiro, Brazil., Calmy A; Division of Infectious Diseases, Geneva University Hospitals, Faculty of Medicine, Geneva, Switzerland.; Department of Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland., Team FTCS; Department of Infectious Diseases and Hospital Epidemiology, University of Basel, Basel, Switzerland.; Division of Infectious Diseases, Geneva University Hospitals, Faculty of Medicine, Geneva, Switzerland.; Lab. De Pesquisa Clinica DST/AIDS, Instituto Nacional de Infectologia Evandro Chagas, Fiocruz, Rio de Janeiro, Brazil.; Division of Infectious Diseases, Ospedale Regionale di Lugano and Faculty of Medicine, University of Southern Switzerland, Lugano, Switzerland.

Publikováno v: EClinicalMedicine [EClinicalMedicine] 2021 Dec; Vol. 42, pp. 101188. Date of Electronic Publication: 2021 Nov 06.