Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Tea Shuvaeva"'
Autor:
Jacob S. Brenner, Daniel C. Pan, Jacob W. Myerson, Oscar A. Marcos-Contreras, Carlos H. Villa, Priyal Patel, Hugh Hekierski, Shampa Chatterjee, Jian-Qin Tao, Hamideh Parhiz, Kartik Bhamidipati, Thomas G. Uhler, Elizabeth D. Hood, Raisa Yu. Kiseleva, Vladimir S. Shuvaev, Tea Shuvaeva, Makan Khoshnejad, Ian Johnston, Jason V. Gregory, Joerg Lahann, Tao Wang, Edward Cantu, William M. Armstead, Samir Mitragotri, Vladimir Muzykantov
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Unwanted uptake in the liver and limited accumulation in target organs is a major obstacle to targeted drug delivery. Here, the authors report on the hitchhiking of nanocarriers on red blood cells and the targeted upstream delivery to different targe
Externí odkaz:
https://doaj.org/article/362e0eed733347a8aa0df110774ccc31
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 10, Pp 2306-2318 (2007)
Peroxiredoxin 6 (Prdx6) is a bifunctional protein with glutathione peroxidase and phospholipase A2 (PLA2) activities, and it alone among mammalian peroxiredoxins can hydrolyze phospholipids. After identifying a potential catalytic triad (S32, H26, D1
Externí odkaz:
https://doaj.org/article/8fbef6749cd54991be2930cc33a12ffb
Autor:
Patrick M. Glassman, Carlos H. Villa, Oscar A. Marcos-Contreras, Elizabeth D. Hood, Landis R. Walsh, Colin F. Greineder, Jacob W. Myerson, Tea Shuvaeva, Laura Puentes, Jacob S. Brenner, Don L. Siegel, Vladimir R. Muzykantov
Publikováno v:
Bioconjugate Chemistry. 33:1286-1294
Engineering drug delivery systems for prolonged pharmacokinetics (PK) has been an ongoing pursuit for nearly 50 years. The gold standard for PK enhancement is the coating of nanoparticles with polymers, namely polyethylene glycol (PEGylation), which
Autor:
Laura T. Ferguson, Elizabeth D. Hood, Tea Shuvaeva, Vladimir V. Shuvaev, Maria C. Basil, Zhicheng Wang, Jia Nong, Xiaonan Ma, Jichuan Wu, Jacob W. Myerson, Oscar A. Marcos-Contreras, Jeremy Katzen, Justine M. Carl, Edward E. Morrisey, Edward Cantu, Carlos H. Villa, Samir Mitragotri, Vladimir R. Muzykantov, Jacob S. Brenner
Publikováno v:
ACS Nano
A long-standing goal of nanomedicine is to improve a drug’s benefit by loading it into a nanocarrier that homes solely to a specific target cell and organ. Unfortunately, nanocarriers usually end up with only a small percentage of the injected dose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27890969e38ca28d17e3ff872c3569de
https://europepmc.org/articles/PMC9339245/
https://europepmc.org/articles/PMC9339245/
Autor:
Vincent M. Rotello, Laura T. Ferguson, Tea Shuvaeva, Nahal Habibi, Colin F. Greineder, David C. Luther, George S Worthen, Priyal Patel, Landis R. Walsh, Jacob W. Myerson, Oscar A. Marcos-Contreras, Jia Nong, Jichuan Wu, Hong-Ying Zhang, Liudmila L. Mazaleuskaya, Marco E Zamora, Joerg Lahann, Ian Johnston, Michael H Zaleski, Jason V. Gregory, Vladimir R. Muzykantov, Raisa Yu Kiseleva, Elizabeth D. Hood, Kathryn M Rubey, Samir Mitragotri, Jacob S. Brenner, Tilo Grosser, Yi-Wei Lee, Patrick M. Glassman
This study shows that the supramolecular arrangement of proteins in nanoparticle structures predicts nanoparticle accumulation in neutrophils in acute lung inflammation (ALI). We observed homing to inflamed lungs for a variety of nanoparticles with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3de3c7e5e03827014748aaac9cf92e29
https://pub.uni-bielefeld.de/record/2965299
https://pub.uni-bielefeld.de/record/2965299
Autor:
Vladimir V. Shuvaev, J. S. Brenner, Vladimir R. Muzykantov, Elizabeth D. Hood, Laura T. Ferguson, Tea Shuvaeva
Publikováno v:
A64. THERAPEUTICS, DRUG DELIVERY, AND TISSUE ENGINEERING.
Autor:
Michael H Zaleski, Landis R. Walsh, Ian Johnston, Yi-Wei Lee, Raisa Yu Kiseleva, Laura T. Ferguson, Nahal Habibi, David C. Luther, Kathryn M Rubey, Priyal Patel, Colin F. Greineder, Patrick M. Glassman, George S Worthen, Samir Mitragotri, Tea Shuvaeva, Jason V. Gregory, Jacob W. Myerson, Oscar A. Marcos-Contreras, Jia Nong, Vincent M. Rotello, Vladimir R. Muzykantov, Joerg Lahann, Marco E Zamora, Jacob S. Brenner, Elizabeth D. Hood
Acute lung inflammation has severe morbidity, as seen in COVID-19 patients. Lung inflammation is accompanied or led by massive accumulation of neutrophils in pulmonary capillaries (“margination”). We sought to identify nanostructural properties t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bc962ac186718faf7a79ed5b27ef4f7
https://doi.org/10.1101/2020.04.15.037564
https://doi.org/10.1101/2020.04.15.037564
Autor:
Elizabeth D. Hood, Tea Shuvaeva, Carlos H. Villa, Colin F. Greineder, Vladimir R. Muzykantov, Landis R. Walsh
Publikováno v:
Bioconjugate Chemistry. 29:3626-3637
Liposomes are a proven, versatile, and clinically viable technology platform for vascular delivery of drugs and imaging probes. Although targeted liposomes have the potential to advance these applications, complex formulations and the need for optima
Autor:
William M. Armstead, Jason V. Gregory, Carlos H. Villa, Raisa Yu Kiseleva, Vladimir S. Shuvaev, Hamideh Parhiz, Tao Wang, Priyal Patel, Tea Shuvaeva, Jacob W. Myerson, Oscar A. Marcos-Contreras, Hugh Hekierski, Ian Johnston, Samir Mitragotri, Makan Khoshnejad, Thomas G. Uhler, Joerg Lahann, Jian-Qin Tao, Edward Cantu, Shampa Chatterjee, Kartik Bhamidipati, Vladimir R. Muzykantov, Elizabeth D. Hood, Jacob S. Brenner, Daniel C. Pan
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications
Nature Communications
Drug delivery by nanocarriers (NCs) has long been stymied by dominant liver uptake and limited target organ deposition, even when NCs are targeted using affinity moieties. Here we report a universal solution: red blood cell (RBC)-hitchhiking (RH), in
Autor:
Ferguson, Laura T., Hood, Elizabeth D., Tea Shuvaeva, Shuvaev, Vladimir V., Basil, Maria C., Zhicheng Wang, Jia Nong, Xiaonan Ma, Jichuan Wu, Myerson, Jacob W., Marcos-Contreras, Oscar A., Katzen, Jeremy, Carl, Justine M., Morrisey, Edward E., Cantu, Edward, Villa, Carlos H., Mitragotri, Samir, Muzykantov, Vladimir R., Brenner, Jacob S.
Publikováno v:
ACS Nano; 3/22/2022, Vol. 16 Issue 3, p4666-4683, 18p