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Mixtures of Intrinsically Disordered Neuronal Protein Tau and Anionic Liposomes Reveal Distinct Anionic Liposome-Tau Complexes Coexisting with Tau Liquid-Liquid Phase Separated Coacervates.

Autor: Tchounwou C; Materials Department, University of California, Santa Barbara, California 93106, USA.; Molecular, Cellular, and Developmental Biology Department, University of California, Santa Barbara, California 93106, USA.; These authors contributed equally., Jobanputra AJ; Materials Department, University of California, Santa Barbara, California 93106, USA.; Molecular, Cellular, and Developmental Biology Department, University of California, Santa Barbara, California 93106, USA.; Biomolecular Science & Engineering Program, University of California, Santa Barbara, California 93106, USA.; These authors contributed equally., Lasher D; Materials Department, University of California, Santa Barbara, California 93106, USA.; Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106, USA., Fletcher BJ; Materials Department, University of California, Santa Barbara, California 93106, USA.; Biomolecular Science & Engineering Program, University of California, Santa Barbara, California 93106, USA., Jacinto J; Materials Department, University of California, Santa Barbara, California 93106, USA.; Molecular, Cellular, and Developmental Biology Department, University of California, Santa Barbara, California 93106, USA., Bhaduri A; Materials Department, University of California, Santa Barbara, California 93106, USA.; Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106, USA., Best RL; Molecular, Cellular, and Developmental Biology Department, University of California, Santa Barbara, California 93106, USA.; Neuroscience Research Institute, University of California, Santa Barbara, California 93106, USA., Fisher WS; Materials Department, University of California, Santa Barbara, California 93106, USA.; Biomolecular Science & Engineering Program, University of California, Santa Barbara, California 93106, USA., Ewert KK; Materials Department, University of California, Santa Barbara, California 93106, USA., Li Y; Materials Research Laboratory, University of California, Santa Barbara, California 93106, USA., Feinstein SC; Molecular, Cellular, and Developmental Biology Department, University of California, Santa Barbara, California 93106, USA.; Neuroscience Research Institute, University of California, Santa Barbara, California 93106, USA., Safinya CR; Materials Department, University of California, Santa Barbara, California 93106, USA.; Molecular, Cellular, and Developmental Biology Department, University of California, Santa Barbara, California 93106, USA.; Biomolecular Science & Engineering Program, University of California, Santa Barbara, California 93106, USA.; Department of Physics, University of California, Santa Barbara, California 93106, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jul 17. Date of Electronic Publication: 2024 Jul 17.