Zobrazeno 1 - 2
of 2
pro vyhledávání: '"TbNTR, T. brucei NTR"'
Autor:
Shane R. Wilkinson, William D. Bloomer, Marcel Kaiser, Maria V. Papadopoulou, Howard S. Rosenzweig, Joanna Szular
Publikováno v:
European Journal of Medicinal Chemistry
A small series of 5-nitro-2-aminothiazole-based amides containing arylpiperazine-, biphenyl- or aryloxyphenyl groups in their core were synthesized and evaluated as antitrypanosomatid agents. All tested compounds were active or moderately active agai
Autor:
Papadopoulou, Maria V., Bloomer, William D., Rosenzweig, Howard S., Wilkinson, Shane R., Szular, Joanna, Kaiser, Marcel
Publikováno v:
European Journal of Medicinal Chemistry
3-Nitro-1H-1,2,4-triazole-based acetamides bearing a biphenyl- or a phenoxyphenyl moiety have shown remarkable antichagasic activity both in vitro and in an acute murine model, as well as substantial in vitro antileishmanial activity but lacked activ