Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Tayna S. Valerio"'
Autor:
Daniela Sales Alviano Moreno, Patricia Dias Fernandes, Darlisson de Alexandria Santos, Péricles Barreto Alves, Celuta S. Alviano, Dayana da Costa Salomé, Natália de Morais Cordeiro, Tayna S. Valerio
Publikováno v:
Biomedicines, Vol 8, Iss 111, p 111 (2020)
Biomedicines
Volume 8
Issue 5
Biomedicines
Volume 8
Issue 5
Aristolochia trilobata, popularly known as &ldquo
mil-homens,&rdquo
is widely used for treatment of stomach aches, colic, asthma, pulmonary diseases, diabetes, and skin affection. We evaluated the antinociceptive and anti-inflammatory activ
mil-homens,&rdquo
is widely used for treatment of stomach aches, colic, asthma, pulmonary diseases, diabetes, and skin affection. We evaluated the antinociceptive and anti-inflammatory activ
Autor:
Natália de Morais Cordeiro, Patricia Dias Fernandes, Carlos A. M. Fraga, Marina Amaral Alves, Patricia Ribeiro de Carvalho, Laurent E. Dardenne, Tayna S. Valerio, Lídia Moreira Lima, Isabella A. Guedes, Eliezer J. Barreiro, Rosana H. C. N. Freitas
Publikováno v:
Chemical biologydrug design. 91(2)
Protein kinases constitute attractive therapeutic targets for development of new prototypes to treat different chronic diseases. Several available drugs, like tinibs, are tyrosine kinase inhibitors; meanwhile, inhibitors of serine/threonine kinases,
Autor:
Laurent E. Dardenne, Patricia Dias Fernandes, Rosana H. C. N. Freitas, Natália de Morais Cordeiro, Carlos A. M. Fraga, Isabella A. Guedes, Thaís S. do Nascimento, Tayna S. Valerio
Publikováno v:
ChemMedChem. 11(2)
Inhibitor of nuclear factor κB kinase 2 (IKK2) is suggested to be a potential target for the development of novel anti-inflammatory and anticancer drugs. In this work, we applied structure-based drug design to improve the potency of the inhibitor (E