Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Taylor S Jefferson"'
Autor:
Suzanne O Nolan, Samantha L Hodges, Matthew S Binder, Gregory D Smith, James T Okoh, Taylor S Jefferson, Brianna Escobar, Joaquin N Lugo
Publikováno v:
PLoS ONE, Vol 17, Iss 1, p e0262916 (2022)
The current study aimed to further address important questions regarding the therapeutic efficacy of omega-3 fatty acids for various behavioral and neuroimmune aspects of the Fmr1 phenotype. To address these questions, our experimental design utilize
Externí odkaz:
https://doaj.org/article/820e9c2234be40e4a849a85b25441efb
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0143134 (2015)
Fragile X syndrome (FXS) develops from excessive trinucleotide CGG repeats in the 5'-untranslated region at Xq27.3 of the Fmr-1 gene, which functionally silences its expression and prevents transcription of its protein. This disorder is the most prom
Externí odkaz:
https://doaj.org/article/631d62c979c947ce8d6cf8e21f7de913
Autor:
Suzanne O. Nolan, Andrew J. Holley, Samantha L. Hodges, Taylor S. Jefferson, Joaquin N. Lugo, Conner D. Reynolds, Gregory D. Smith
Publikováno v:
Neuroreport
The purpose of this investigation was to examine cerebellar levels of several molecular signaling pathways, including PI3K/AKT/mammalian target of rapamycin (mTOR) signaling and markers of neuronal migration, following loss of the phosphatase and ten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bfd29935aaffe209f367657a3481309
https://doi.org/10.1097/wnr.0000000000001241
https://doi.org/10.1097/wnr.0000000000001241
Autor:
Suzanne O. Nolan, Samantha L. Hodges, Matthew S. Binder, Gregory D. Smith, James T. Okoh, Taylor S. Jefferson, Brianna Escobar, Joaquin N. Lugo
The current study aimed to further address important questions regarding the therapeutic efficacy of omega-3 fatty acids for various behavioral and neuroimmune aspects of theFmr1phenotype. To address these questions, our experimental design utilized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2143f3ad45748b81f630cf23598ba356
https://doi.org/10.1101/2021.04.16.440191
https://doi.org/10.1101/2021.04.16.440191
Autor:
Suzanne O. Nolan, Conner D. Reynolds, Samantha L. Hodges, Taylor S. Jefferson, Joaquin N. Lugo, Amy L. Brewster, Gregory D. Smith
Publikováno v:
Neuroreport
Objective Focal cortical dysplasia (FCD) accounts for nearly half of all cases of medically refractory epilepsy in the pediatric and adult patient populations. This neurological disorder stems from localized malformations in cortical brain tissue due
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecfed2b7b6f1b53197c05b11e9cfcc7b
https://europepmc.org/articles/PMC9621172/
https://europepmc.org/articles/PMC9621172/
Autor:
Joaquin N. Lugo, Suzanne O. Nolan, Samantha L. Hodges, Conner D. Reynolds, Gregory D. Smith, Taylor S. Jefferson
Publikováno v:
NeuroReport. 29:1109-1113
Dysregulation of the PI3K/Akt/mTOR signaling cascade has been associated with the pathology of neurodegenerative disorders, specifically Alzheimer's disease (AD). Both in-vivo models and post-mortem brain samples of individuals with AD have commonly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbd5d168da49c2b4e830feefe1548b92
https://doi.org/10.1097/wnr.0000000000001081
https://doi.org/10.1097/wnr.0000000000001081
Publikováno v:
NeuroReport. 27:1331-1335
Fragile X syndrome is a neurodevelopmental disorder caused by a trinucleotide (CGG) hyperexpansion in the FMR1 gene, functionally silencing transcription of the fragile X mental retardation protein (FMRP). This disorder is characterized by impaired c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e3f50c02fa8dd0efc62dda218c37991
https://doi.org/10.1097/wnr.0000000000000701
https://doi.org/10.1097/wnr.0000000000000701
Autor:
Taylor S. Jefferson, Gregory D. Smith, Conner D. Reynolds, Joaquin N. Lugo, Samantha L. Hodges, Andrew J. Holley, Suzanne O. Nolan
Publikováno v:
CNS & Neurological Disorders - Drug Targets. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6f67ca6f3f19bacc3144df5bd401129
https://doi.org/10.2174/1871527318666190312122753
https://doi.org/10.2174/1871527318666190312122753
Autor:
Jessica B. Morrison, Taylor S. Jefferson, Jessika White, Joaquin N. Lugo, Suzanne O. Nolan, Samantha L. Hodges, Nan Gao, Gregory D. Smith, Conner D. Reynolds
Publikováno v:
Brain research. 1699
The canonical Wnt and PI3K/Akt/mTOR pathways both play critical roles in brain development early in life. There is extensive evidence of how each pathway is involved in neuronal and synaptic maturation, however, how these molecular networks interact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3208e078ffc1239570de0a00d7be718d
https://pubmed.ncbi.nlm.nih.gov/30086265
https://pubmed.ncbi.nlm.nih.gov/30086265
Autor:
Conner D. Reynolds, Taylor S. Jefferson, Meagan Volquardsen, Ashvini Pandian, Gregory D. Smith, Andrew J. Holley, Joaquin N. Lugo
Publikováno v:
F1000Research, Vol 6 (2018)
Background: The piracetam analog, aniracetam, has recently received attention for its cognition enhancing potential, with minimal reported side effects. Previous studies report the drug to be effective in both human and non-human models with pre-exis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::6c2b4521806a89dfe26704e2a5b97399
https://f1000research.com/articles/6-1452/v3
https://f1000research.com/articles/6-1452/v3