Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Taylor M Parker"'
Autor:
Xiaona Chu, Yue Wang, Harikrishna Nakshatri, Taylor M. Parker, Yunlong Liu, Duojiao Chen, Poornima Bhat-Nakshatri
Publikováno v:
Oncogene. 40:1332-1346
Chromatin accessibility is central to basal and inducible gene expression. Through ATAC-seq experiments in estrogen receptor-positive (ER+) breast cancer cell line MCF-7 and integration with multi-omics data, we found estradiol (E2) induced chromatin
Publikováno v:
Trends in Cancer. 6:732-736
Within heterogeneous tumors, cancer cells are constantly interacting. Cell competition (CC) is a fitness-based selection mechanism that results in increased proliferation of discrete populations at the expense of their less fit neighbors. CC-based se
Publikováno v:
Seminars in Cancer Biology. 63:1-10
Cancers exhibit a remarkable degree of intratumoral heterogeneity (ITH), which results from complex cellular interactions amongst various cell types. This phenomenon provides an opportunity for clonal selection and growth advantages to aggressive can
Autor:
Kyoung-Jae Won, Rajan Gogna, Michail Yekelchyk, Taylor M Parker, Esha Madan, Kartik Gupta, Steven R Grossman, Paul B. Fisher, António M Palma, Eduardo Moreno
Publikováno v:
EMBO J
Tumors are complex cellular and acellular environments within which cancer clones are under continuous selection pressures. Cancer cells are in a permanent mode of interaction and competition with each other as well as with the immediate microenviron
Autor:
Maria Leonor Peixoto, Rajan Gogna, Esha Madan, Aliya Chandaria, Eduardo Moreno, Carlos Alfredo Lopes de Carvalho, Joaquim Cabral-Teixeira, Antonio Beltran, Uttam Pati, Ana R. Tomás, Periannan Kuppusamy, António M Palma, Vanessa Henriques, Christopher J Pelham, Antonio Galzerano, Taylor M. Parker, Masaki Nagane, Karuppaiyah Selvendiran, Rita Canas-Marques
Publikováno v:
Nucleic Acids Research
Chronic hypoxia is associated with a variety of physiological conditions such as rheumatoid arthritis, ischemia/reperfusion injury, stroke, diabetic vasculopathy, epilepsy and cancer. At the molecular level, hypoxia manifests its effects via activati
Autor:
Laura A. Hansen, Tadashi Yamashita, Denise Camacho, David Soldini, Rajan Gogna, Steven R. Post, Esha Madan, Vanessa Henriques, Hiroko Yamashita, Ana I. S. Vieira, Youzhong Yuan, Kranti Shaik, António M Palma, Carlos Carvalho, Periannan Kuppusamy, Antonio Beltran, Antonio Galzerano, Masaki Nagane, Rita Canas-Marques, Kimberly Fazio, Davide Accardi, Eduardo Moreno, Harikrishna Nakshatri, Christa Rhiner, Taylor M. Parker, Miguel Alexandre Ferreira Pinto, Christopher J. Pelham
Publikováno v:
Nature. 572:260-264
In humans, the adaptive immune system uses the exchange of information between cells to detect and eliminate foreign or damaged cells; however, the removal of unwanted cells does not always require an adaptive immune system1,2. For example, cell sele
Autor:
Grace A. Ledet, Shukla Biswas, Vidya P. Kumar, Richard A. Graves, Demaurian M. Mitchner, Taylor M. Parker, Levon A. Bostanian, Sanchita P. Ghosh, Tarun K. Mandal
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 1, p 28 (2016)
The purpose of this study was two-fold: (1) to formulate γ-tocotrienol (GT3) in a nanoemulsion formulation as a prophylactic orally administered radioprotective agent; and (2) to optimize the storage conditions to preserve the structural integrity o
Externí odkaz:
https://doaj.org/article/d3b63087a5604c699f2ef1fd71d9afcc
Autor:
Duojiao, Chen, Taylor M, Parker, Poornima, Bhat-Nakshatri, Xiaona, Chu, Yunlong, Liu, Yue, Wang, Harikrishna, Nakshatri
Publikováno v:
Oncogene. 40(7)
Chromatin accessibility is central to basal and inducible gene expression. Through ATAC-seq experiments in estrogen receptor-positive (ER+) breast cancer cell line MCF-7 and integration with multi-omics data, we found estradiol (E2) induced chromatin
Publikováno v:
Clinical Cancer Research. 27:PR-10
Objective: Colorectal cancer (CRC) is the 3rd most common cancer in the United States. Despite declining incidence in patients older than 50, there has been an increasing trend of CRC in patients under the age of 50. Some risk factors such as inflamm
Autor:
Joshua R. Rabang, Devendra K. Agrawal, Austin Huy Nguyen, Arun Angelo Patil, Taylor M. Parker
Publikováno v:
Brain Injury. 31:2-8
Traumatic brain injuries (TBI) are associated with complex inflammatory pathways that lead to the development of secondary injuries such as cerebral ischaemia, elevated intracranial pressure and cognitive deficits. The association between intracellul