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Autor:
Taylor Lg Doyle, Jeremy S. Disch, George P. Vlasuk, Christine Loh, Ana P. Gomes, Basil P. Hubbard, Jun Li, James L. Ellis, Sean M. Armour, David A. Sinclair, Quinn Lu
Publikováno v:
Cell Cycle. 12:2233-2240
SIRT1 is an NAD (+) -dependent deacetylase that counteracts multiple disease states associated with aging and may underlie some of the health benefits of calorie restriction. Understanding how SIRT1 is regulated in vivo could therefore lead to new st