Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Taylor L. Jacobson"'
Autor:
Doo Sup Choi, David A. Mrazek, David J. Hinton, Prasanna K. Mishra, Mark A. Frye, Slobodan Macura, Moonnoh R. Lee, Taylor L. Jacobson
Publikováno v:
Neuropharmacology. 62:2480-2488
Acamprosate is clinically used to treat alcohol-dependent patients. While the molecular and pharmacological mechanisms of acamprosate remain unclear, it has been shown to regulate γ-aminobutyric acid (GABA) or glutamate levels in the cortex and stri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fff62720bf1ac7a17e2b77bb4dc43872
https://doi.org/10.1016/j.neuropharm.2012.02.022
https://doi.org/10.1016/j.neuropharm.2012.02.022
Publikováno v:
Tetrahedron Letters. 54:6804-6806
Tryptanthrin is a natural product with numerous important pharmacological properties. Tryptanthrin and its analogs are commonly prepared by condensation of isatoic anhydride and isatin. In this Letter we investigate the formation of tryptanthrin deri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de157a4bf6e2e26e40e45cf1a7bb70b5
https://doi.org/10.1016/j.tetlet.2013.09.124
https://doi.org/10.1016/j.tetlet.2013.09.124
Publikováno v:
ChemInform. 45
In general, the synthesis of tryptanthrin derivatives by Oxone-induced dimerization of the corresponding indole-3-carbaldehydes appears to be limited to 5-halo substituted compounds.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2976c63612b1bf89b8201f2d9313eb5
https://doi.org/10.1002/chin.201416190
https://doi.org/10.1002/chin.201416190
Autor:
Nikolas J. Czerniecki, Amber C. Nelson, Peter Grundt, Emily S. Kalinowski, Taylor L. Jacobson
Publikováno v:
Organic & Biomolecular Chemistry. 11:7455
A recent report has indicated that the oxidizing agent Oxone does not possess the ability to cleave the 2,3-carbon-carbon bond of indole. Work in our laboratory shows that this is not the case. Indole and a variety of aryl ring substituted derivative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99882b618b1fead989e698eb25f8177a
https://doi.org/10.1039/c3ob41802b
https://doi.org/10.1039/c3ob41802b