Zobrazeno 1 - 10 of 11 pro vyhledávání: '"Taylor Kredel"'
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OR19-03 Effects of Nonpeptide Orally Bioavailable ACTH Antagonists on Adrenal Gland Size and Function in Rats
Autor: Melissa Fowler, Taylor Kredel, Rosa Luo, Stacy Markison, Shirley Cruz, Ana Karin Kusnetzow, Stephen F. Betz, Scott Struthers, Oleg Tsivkovski, Michael Johns, Agnes Antwan, Greg J. Reinhart, Jon Athanacio, Ajay Madan
Publikováno v: Journal of the Endocrine Society
Cushing’s disease (CD) and Ectopic ACTH syndrome (EAS) stem from excess circulating adrenocorticotropic hormone (ACTH) and resulting hypercortisolemia. In CD, excess ACTH is secreted from pituitary tumors, whereas excess ACTH in EAS arises from non
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cabd2ca03573ef4171b9289897a6290
http://europepmc.org/articles/PMC7209714
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5
The Spatiotemporal Neural Dynamics of Infant Face Processing
Autor: Amanda C. Hahn, Taylor Kredel, Benjamin Ratcliff, Nikal Toor, Lawrence A. Symons, Kelly J. Jantzen, McNeel G. Jantzen
Publikováno v: Adaptive Human Behavior and Physiology. 3:386-400
Substantial evidence indicates that infant faces are a salient stimulus that receive attentional priority, motivate caretaking behavior, and are rewarding. There is strong support for an early role of reward circuitry, including the orbital frontal c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c588f3ece1795a4ddbbe0b26e49fc9c2
https://doi.org/10.1007/s40750-017-0080-1
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6
SAT-260 Selective Nonpeptide Somatostatin Subtype 5 (sst5) Agonists Suppress Induced Insulin Secretion in Pancreatic Islets from both Rats and Healthy Human Donors
Autor: Taylor Kredel, Melissa Fowler, Ana Karin Kusnetzow, Jian Zhao, Elizabeth Rico-Bautista, Yun Fei Zhu, Shimiao Wang, Stephen F. Betz, Stacy Markison, Jon Athanacio, Scott Struthers
Publikováno v: Journal of the Endocrine Society
Hyperinsulinemia is a heterogeneous condition in which dangerously low blood sugar levels are caused by improperly regulated insulin secretion from pancreatic ß-cells. The most severe form of hyperinsulinemia arises from congenital hyperinsulinism (
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e72ae643bc4bc6d9dd781e8b9dca7bc9
https://doi.org/10.1210/js.2019-sat-260
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7
SAT-364 Nonpeptide Orally-Bioavailable ACTH Antagonists: Suppression of ACTH-Induced Corticosterone Secretion and Adrenal Hypertrophy in Rats
Autor: Ana Karin Kusnetzow, Scott Struthers, Michael Johns, Julie Nguyen, Elizabeth Rico-Bautista, Taylor Kredel, Rosa Luo, Yun Fei Zhu, Stacy Markison, Melissa Fowler, Stephen F. Betz, Greg J. Reinhart, Sun Hee Kim, Christine Staley, Sangdon Han, Hannah Tan, Jon Athanacio, Ajay Madan
Publikováno v: Journal of the Endocrine Society
Cushing’s disease is most commonly the result of a microadenoma derived from pituitary corticotrophic cells that secretes excess adrenocorticotropic hormone (ACTH). ACTH is an important modulator of steroidal hormone synthesis and secretion from th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb12b3ec79375e92bb4f3965d9b17dc1
https://doi.org/10.1210/js.2019-sat-364
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8
SAT-169 Selective Nonpeptide Somatostatin Subtype 5 (sst5) Agonists Suppress Glucose- and Sulfonylurea-Induced Insulin Secretion in Rats
Autor: Ana Karin Kusnetzow, Michael Johns, Stacy Markison, Stephen F. Betz, Shimiao Wang, Yun Fei Zhu, Melissa Fowler, Jon Athanacio, Ajay Madan, Scott Struthers, Taylor Kredel, Jian Zhao, Rosa Luo, Emmanuel Sturchler
Publikováno v: Journal of the Endocrine Society
Congenital hyperinsulinism (CHI) results from mutations within the insulin secretion pathway and is characterized by excessive and/or inappropriate insulin secretion by pancreatic islet β-cells. CHI is the most common cause of persistent hypoglycemi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::783c4c12e1c369293497cf179ab4b256
http://europepmc.org/articles/PMC6552315
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9
Effects of CRN04894, a Nonpeptide Orally Bioavailable ACTH Antagonist, on Corticosterone in Rodent Models of ACTH Excess
Autor: Scott Struthers, Rosa Luo, Stacy Markison, Yun Fei Zhu, Ana Karin Kusnetzow, Stephen F. Betz, Michael Johns, Greg J. Reinhart, Oleg Tsivkovski, Sun Hee Kim, Melissa Fowler, Agnes Antwan, Jon Athanacio, Ajay Madan, Sangdon Han, Taylor Kredel
Publikováno v: Journal of the Endocrine Society
CRN04894 is an orally administered nonpeptide that is a potent and selective antagonist for adrenocorticotropic hormone (ACTH) acting at the melanocortin 2 receptor (MC2R) and is currently under development for the treatment of diseases of ACTH exces
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51748c85eb466d9c50cae9ea5ad4c81b
http://europepmc.org/articles/PMC8090401
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10
Early and late event-related potentials are modulated by infant and adult faces of high and low attractiveness
Autor: Kevin Hanson, Lianne Hodgson, Taylor Kredel, Amanda C. Hahn, Lawrence A. Symons, Lori Schiavone, Kelly J. Jantzen
Publikováno v: Social neuroscience. 11(2)
The processing of infant faces may be somewhat distinct from that of adult faces. Indeed, recent neuroimaging studies have provided evidence of an early, “baby-specific” neural response whereby infant faces are perceived more rapidly than adult f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e504b211c46977754c522304440291fe
https://pubmed.ncbi.nlm.nih.gov/26160142
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