Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Taylor K. Farley"'
Autor:
Sarah S. Geiger, Javier Traba, Nathan Richoz, Taylor K. Farley, Stephen R. Brooks, Franziska Petermann, Lingdi Wang, Frank J. Gonzalez, Michael N. Sack, Richard M. Siegel
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Time of day influences immune responses and lethality in response to LPS, with survival greatest at the beginning compared to the end of the light cycle. Here the authors show that feeding, rather than light, controls time-of-day dependent LPS sensit
Externí odkaz:
https://doaj.org/article/c006a892d73b44e6afaa5d1292253d77
Autor:
Verena M. Link, Rose-Marie Karlsson, Jigar V. Desai, Han-Yu Shih, Ai Ing Lim, Oliver J. Harrison, Michail S. Lionakis, Heather A. Cameron, Seong-Ji Han, Taryn McFadden, Taylor K. Farley, Apollo Stacy, Djalma S. Lima-Junior, Yasmine Belkaid
Publikováno v:
Science
Mom’s IL-6 rewires baby’s gut immunity Most infections that occur during pregnancy are mild and transient. However, whether such pathogen encounters can shape the long-term trajectory of the offspring’s immune system remains unclear. Lim et al
Autor:
Satoshi Kubo, Jill M. Fritz, Hayley M. Raquer-McKay, Rhea Kataria, Ivan Vujkovic-Cvijin, Ahmad Al-Shaibi, Yikun Yao, Lixin Zheng, Juan Zou, Alex D. Waldman, Xinyi Jing, Taylor K. Farley, Ann Y. Park, Andrew J. Oler, Adrian K. Charles, Melanie Makhlouf, Eman H. AbouMoussa, Reem Hasnah, Luis R. Saraiva, Sundar Ganesan, Abdulrahman Ahmed Al-Subaiey, Helen Matthews, Emilio Flano, Hyun Hee Lee, Alexandra F. Freeman, Asena Pınar Sefer, Ersin Sayar, Erkan Çakır, Elif Karakoc-Aydiner, Safa Baris, Yasmine Belkaid, Ahmet Ozen, Bernice Lo, Michael J. Lenardo
Publikováno v:
Nature immunology. 23(1)
We report a pleiotropic disease due to loss-of-function mutations in RHBDF2, the gene encoding iRHOM2, in two kindreds with recurrent infections in different organs. One patient had recurrent pneumonia but no colon involvement, another had recurrent
Autor:
Michael N. Sack, Stephen R. Brooks, Taylor K. Farley, Richard M. Siegel, Lingdi Wang, Nathan Richoz, Javier Traba, Sarah S. Geiger, Frank J. Gonzalez, Franziska Petermann
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Digital.CSIC. Repositorio Institucional del CSIC
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Digital.CSIC. Repositorio Institucional del CSIC
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In mice, time of day strongly influences lethality in response to LPS, with survival greatest at the beginning compared to the end of the light cycle. Here we show that feeding, rather than light, controls time-of-day dependent LPS sensitivity. Morta
Publikováno v:
Annual review of immunology. 39
The immune system has coevolved with extensive microbial communities living on barrier sites that are collectively known as the microbiota. It is increasingly clear that microbial antigens and metabolites engage in a constant dialogue with the immune
Autor:
Han-Yu Shih, Heather A. Cameron, Rose-Marie Karlsson, Ai Ing Lim, Yasmine Belkaid, Oliver J. Harrison, Taryn McFadden, Seong-Ji Han, Verena M. Link, Apollo Stacy, Taylor K. Farley
The mammalian immune system has evolved in the face of microbial exposure. How maternal infection experienced at distinct developmental stages shapes the offspring immune system remains poorly understood. Here we show that during pregnancy, maternall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75c0a60d22df4149b2d3bd8aa857ddf3
https://doi.org/10.1101/2021.01.13.426542
https://doi.org/10.1101/2021.01.13.426542
Autor:
Nicholas Collins, Verena M. Link, George Kassiotis, Erin Y. Chen, Michael G. Constantinides, Jan Attig, Christophe Cataisson, Yasmine Belkaid, Djalma S. Lima-Junior, G. I. Koroleva, Taylor K. Farley, Stuart H. Yuspa, Michel Enamorado, Nicolas Bouladoux, Michael A. Fischbach, Louis Gil, Ai Ing Lim, Siddharth R. Krishnamurthy, Indira Rao, Seong-Ji Han
Publikováno v:
Cell
Summary The microbiota plays a fundamental role in regulating host immunity. However, the processes involved in the initiation and regulation of immunity to the microbiota remain largely unknown. Here, we show that the skin microbiota promotes the di
Autor:
Taylor K. Farley, In Ah Choi, Geoffrey M. Thiele, Kevin D. Deane, Jill M. Norris, Eric T. Hawley, Sabina R. Mian, Eun Young Lee, Michael M. Ward, Naveen Gara, Peter K. Gregersen, V. Michael Holers, James R. O'Dell, Yun-Jeong Song, John Botson, Arianne C. Richard, Françoise Meylan, William Stohl, Ted R. Mikuls, Bartlett C. Hamilton, Christopher D. Ward, Theo Heller, David M. Lee, Thi-Sau Migone, S. Lamberth, Richard M. Siegel, Yoo Jin Hong, Yeong Wook Song, M. Kristen Demoruelle
Publikováno v:
Arthritis Research & Therapy
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-14 (2020)
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-14 (2020)
Background The tumor necrosis factor (TNF) superfamily cytokine TNF-like protein 1A (TL1A) and its receptor DR3 are essential for diverse animal models of autoimmune disease and may be pathogenic in rheumatoid arthritis (RA). However, the relationshi
Autor:
Julie A. Moreno, Sarah J. Kane, Taylor K. Farley, Glenn C. Telling, Jason C. Bartz, Joshua Estep, Elizabeth O. Gordon, Mark D. Zabel, Matthew C. Pickering, Heather Bender
Several complement proteins exacerbate prion disease, including C3, C1q, and CD21/35. These proteins of the complement cascade likely increase uptake, trafficking, and retention of prions in the lymphoreticular system, hallmark sites of early prion p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9f5db7ea0823c8d5191fe29ae5cd30a
https://europepmc.org/articles/PMC5698161/
https://europepmc.org/articles/PMC5698161/
Autor:
Nathan Richoz, Hong-Wei Sun, Richard M. Siegel, Françoise Meylan, Kan Jiang, Chen Yao, Arian Laurence, Erika T. Hayes, Han-Yu Shih, Joshua D. Milner, Taylor K. Farley, Franziska Petermann, John J. O'Shea, Fred P. Davis, Yuan Zhang, Daniella M. Schwartz, Yohei Mikami, Yuka Kanno
Publikováno v:
Immunity. 50:106-120.e10
Summary CD4+ T helper (Th) differentiation is regulated by diverse inputs, including the vitamin A metabolite retinoic acid (RA). RA acts through its receptor RARα to repress transcription of inflammatory cytokines, but is also essential for Th-medi