Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Taylor K. Downs"'
Autor:
Michael S. Schappe, Marta E. Stremska, Gregory W. Busey, Taylor K. Downs, Philip V. Seegren, Suresh K. Mendu, Zachary Flegal, Catherine A. Doyle, Eric J. Stipes, Bimal N. Desai
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Efficient removal of apoptotic cells by phagocytosis underlies tissue development, wound repair, host defense and organ homeostasis. Here, authors identify TRPM7 as a regulator of cargo acidification and Ca2+ signaling during apoptotic cell clearance
Externí odkaz:
https://doaj.org/article/91b4d7f5e2564ec69283f69be2f00ae0
Autor:
Sean R Cuddy, Austin R Schinlever, Sara Dochnal, Philip V Seegren, Jon Suzich, Parijat Kundu, Taylor K Downs, Mina Farah, Bimal N Desai, Chris Boutell, Anna R Cliffe
Publikováno v:
eLife, Vol 9 (2020)
Herpes simplex virus-1 (HSV-1) establishes a latent infection in neurons and periodically reactivates to cause disease. The stimuli that trigger HSV-1 reactivation have not been fully elucidated. We demonstrate HSV-1 reactivation from latently infect
Externí odkaz:
https://doaj.org/article/0fb97c7a33404ae3886ae03f37e70bc9
Autor:
Mina Farah, Sean R Cuddy, Parijat Kundu, Chris Boutell, Philip V. Seegren, Austin R Schinlever, Anna R. Cliffe, Taylor K Downs, Sara Dochnal, Jon B. Suzich, Bimal N. Desai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2012f87b5503d8c76eeca70098c8414e
https://doi.org/10.7554/elife.58037.sa2
https://doi.org/10.7554/elife.58037.sa2
Autor:
Taylor K Downs, Anna R. Cliffe, Sara Dochnal, Mina Farah, Chris Boutell, Jon B. Suzich, Austin R Schinlever, Parijat Kundu, Bimal N. Desai, Philip V. Seegren, Sean R Cuddy
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Herpes simplex virus-1 (HSV-1) establishes a latent infection in neurons and periodically reactivates to cause disease. The stimuli that trigger HSV-1 reactivation have not been fully elucidated. We demonstrate HSV-1 reactivation from latently infect
Autor:
Michael S, Schappe, Marta E, Stremska, Gregory W, Busey, Taylor K, Downs, Philip V, Seegren, Suresh K, Mendu, Zachary, Flegal, Catherine A, Doyle, Eric J, Stipes, Bimal N, Desai
Publikováno v:
Nature communications. 13(1)
Efficient clearance of apoptotic cells by phagocytosis, also known as efferocytosis, is fundamental to developmental biology, organ physiology, and immunology. Macrophages use multiple mechanisms to detect and engulf apoptotic cells, but the signalin
Autor:
Michael S, Schappe, Kalina, Szteyn, Marta E, Stremska, Suresh K, Mendu, Taylor K, Downs, Philip V, Seegren, Michelle A, Mahoney, Sumeet, Dixit, Julia K, Krupa, Eric J, Stipes, Jason S, Rogers, Samantha E, Adamson, Norbert, Leitinger, Bimal N, Desai
Publikováno v:
Immunity. 48(1)
Toll-like receptors (TLRs) sense pathogen-associated molecular patterns to activate the production of inflammatory mediators. TLR4 recognizes lipopolysaccharide (LPS) and drives the secretion of inflammatory cytokines, often contributing to sepsis. W
Autor:
Marta E. Stremska, Taylor K Downs, Rachel J. Olson, Ammasi Periasamy, Joel Kennedy, Philip V. Seegren, Logan R. Harper, Norbert Leitinger, Catherine A. Doyle, Eric L. Stipes, Clint M Upchurch, Bimal N. Desai, Ruofan Cao
Publikováno v:
Cell reports
SUMMARY Phagocytes reallocate metabolic resources to kill engulfed pathogens, but the intracellular signals that rapidly switch the immunometabolic program necessary to fuel microbial killing are not understood. We report that macrophages use a fast
Autor:
Norbert Leitinger, Julia K. Krupa, Kalina Szteyn, Taylor K Downs, Eric J. Stipes, Jason S. Rogers, Bimal N. Desai, Marta E. Stremska, Michelle A. Mahoney, Philip V. Seegren, Michael S. Schappe, Samantha E. Adamson, Suresh K. Mendu, Sumeet Dixit
Publikováno v:
Immunity. 48:59-74.e5
Toll-like receptors (TLRs) sense pathogen-associated molecular patterns to activate the production of inflammatory mediators. TLR4 recognizes lipopolysaccharide (LPS) and drives the secretion of inflammatory cytokines, often contributing to sepsis. W