Maternal diet alters long-term innate immune cell memory in fetal and juvenile hematopoietic stem and progenitor cells in nonhuman primate offspring

Autor: Michael J. Nash, Evgenia Dobrinskikh, Taylor K. Soderborg, Rachel C. Janssen, Diana L. Takahashi, Tyler A. Dean, Oleg Varlamov, Jon D. Hennebold, Maureen Gannon, Kjersti M. Aagaard, Carrie E. McCurdy, Paul Kievit, Bryan C. Bergman, Kenneth L. Jones, Eric M. Pietras, Stephanie R. Wesolowski, Jacob E. Friedman

Publikováno v: Cell Reports, Vol 42, Iss 4, Pp 112393- (2023)

Summary: Maternal overnutrition increases inflammatory and metabolic disease risk in postnatal offspring. This constitutes a major public health concern due to increasing prevalence of these diseases, yet mechanisms remain unclear. Here, using nonhum

Externí odkaz: https://doaj.org/article/61f8abfb16c94221819b0fcca9d1aea3

The gut microbiota in infants of obese mothers increases inflammation and susceptibility to NAFLD

Autor: Taylor K. Soderborg, Sarah E. Clark, Christopher E. Mulligan, Rachel C. Janssen, Lyndsey Babcock, Diana Ir, Bridget Young, Nancy Krebs, Dominick J. Lemas, Linda K. Johnson, Tiffany Weir, Laurel L. Lenz, Daniel N. Frank, Teri L. Hernandez, Kristine A. Kuhn, Angelo D’Alessandro, Linda A. Barbour, Karim C. El Kasmi, Jacob E. Friedman

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)

Infants born to obese mothers have altered microbiome and increased risk of obesity and NAFLD. Here the authors establish causality by showing that maternal obesity-shaped infant gut microbiome induces macrophage dysfunction, inflammation, and diet-i

Externí odkaz: https://doaj.org/article/ae080f0844c14d709b3a8306cb9877f4

Author Correction: The gut microbiota in infants of obese mothers increases inflammation and susceptibility to NAFLD

Autor: Taylor K. Soderborg, Sarah E. Clark, Christopher E. Mulligan, Rachel C. Janssen, Lyndsey Babcock, Diana Ir, Bridget Young, Nancy F. Krebs, Dominick J. Lemas, Linda K. Johnson, Tiffany Weir, Laurel L. Lenz, Daniel N. Frank, Teri L. Hernandez, Kristine A. Kuhn, Angelo D’Alessandro, Linda A. Barbour, Karim C. El Kasmi, Jacob E. Friedman

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-2 (2019)

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Externí odkaz: https://doaj.org/article/b8a5853eb5c549e1aa326e422a27ce5b

Reproductive Health Care in Catholic Facilities

Autor: Maryam Guiahi, Lilian Hoffecker, Taylor K Soderborg, Nichole B Thorne, Jacqueline J. Glover

Publikováno v: Obstetrics & Gynecology. 133:105-115

Given the rise in Catholic ownership of U.S. health care facilities, we aimed to examine reproductive health care provision and patient outcomes. We performed a scoping review, which maps the literature and considers inclusion of studies that are not

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8093a8b66b6c6c04758bfcef393a59af
https://doi.org/10.1097/aog.0000000000003029

Pyrroloquinoline quinone prevents developmental programming of microbial dysbiosis and macrophage polarization to attenuate liver fibrosis in offspring of obese mice

Autor: Charles E. Robertson, Angelo D'Alessandro, Moshe Levi, Jacob E. Friedman, Alba Alfonso-Garcia, Xiaoxin X. Wang, Karen R. Jonscher, Aimee L. Anderson, Evgenia Dobrinskikh, Daniel N. Frank, Rachel C. Janssen, Taylor K. Soderborg, David J. Orlicky, Becky A. de la Houssaye, Alexander Fast, Linda K. Johnson, Eric O. Potma, Karim C. El Kasmi, Julie A. Reisz

Publikováno v: Hepatology Communications
Friedman, JE; Dobrinskikh, E; Alfonso-Garcia, A; Fast, A; Janssen, RC; Soderborg, TK; et al.(2018). Pyrroloquinoline quinone prevents developmental programming of microbial dysbiosis and macrophage polarization to attenuate liver fibrosis in offspring of obese mice.. Hepatology communications, 2(3), 313-328. doi: 10.1002/hep4.1139. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/7pv1r620

Increasingly, evidence suggests that exposure to maternal obesity creates an inflammatory environment in utero, exerting long-lasting postnatal signatures on the juvenile innate immune system and microbiome that may predispose offspring to developmen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eec932e4da99f6c46491938567b43af
https://doi.org/10.1002/hep4.1139