Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Taylor J. Fiolek"'
Autor:
Alam García-Heredia, Amol Arunrao Pohane, Emily S Melzer, Caleb R Carr, Taylor J Fiolek, Sarah R Rundell, Hoong Chuin Lim, Jeffrey C Wagner, Yasu S Morita, Benjamin M Swarts, M Sloan Siegrist
Publikováno v:
eLife, Vol 7 (2018)
Rod-shaped mycobacteria expand from their poles, yet d-amino acid probes label cell wall peptidoglycan in this genus at both the poles and sidewall. We sought to clarify the metabolic fates of these probes. Monopeptide incorporation was decreased by
Externí odkaz:
https://doaj.org/article/d8126d86165d48daa68baa4773114a87
Autor:
Benjamin M. Swarts, Adrian K. Rylski, Taylor J. Fiolek, Herbert W. Kavunja, Nathan J. Holmes, Amol Arunrao Pohane, Nicholas Banahene, M. Sloan Siegrist
Publikováno v:
Chembiochem
Mycobacteria and related organisms in the Corynebacterineae suborder are characterized by a distinctive outer membrane referred to as the mycomembrane. Biosynthesis of the mycomembrane occurs through an essential process called mycoloylation, which i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac454ca4833ff6e4d9eed6f5c58adb54
https://doi.org/10.1002/cbic.201800687
https://doi.org/10.1002/cbic.201800687
Publikováno v:
ACS chemical neuroscience. 12(8)
Oligomerization of aggregation-prone intrinsically disordered proteins (IDPs), such as α-synuclein, amyloid β, and tau, has been shown to be associated with the pathogenesis of several neurodegenerative diseases, including Parkinson's and Alzheimer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80ede711013fc4cf6351a66b0e035f46
https://pubmed.ncbi.nlm.nih.gov/33788542
https://pubmed.ncbi.nlm.nih.gov/33788542
Autor:
Steven B. Davies, Tyler J. Wall, Christopher J. Savich, Jetze J. Tepe, Taylor J. Fiolek, Molly V. Campbell, Christina L. Magyar, R. Adam Mosey
Publikováno v:
Bioorg Med Chem Lett
Aggregates or oligomeric forms of many intrinsically disordered proteins (IDPs), including α-synuclein, are hallmarks of neurodegenerative diseases, like Parkinson's and Alzheimer's disease, and key contributors to their pathogenesis. Due to their d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd5408e1c22d23af94dd1c87b24774e7
https://pubmed.ncbi.nlm.nih.gov/33513387
https://pubmed.ncbi.nlm.nih.gov/33513387
Autor:
Benjamin M. Swarts, Temitope O. Nathan, Hannah N. Foley, Herbert W. Kavunja, Taylor J. Fiolek, Brent F. Piligian
Publikováno v:
Chemical Communications. 52:13795-13798
Protein O-mycoloylation is a unique post-translational lipidation that was recently discovered in Corynebacterium. We describe an alkyne-modified trehalose monomycolate chemical reporter that can metabolically tag O-mycoloylated proteins in C. glutam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1408b8739cc25a6bb800aaf91eb43c03
https://doi.org/10.1039/c6cc07143k
https://doi.org/10.1039/c6cc07143k
Autor:
Sarah R. Rundell, Hoong Chuin Lim, M. Sloan Siegrist, Caleb R. Carr, Amol Arunrao Pohane, Taylor J. Fiolek, Emily S. Melzer, Jeffrey C Wagner, Benjamin M. Swarts, Alam García-Heredia, Yasu S. Morita
Publikováno v:
eLife, Vol 7 (2018)
eLife
eLife
Rod-shaped mycobacteria expand from their poles, yet d-amino acid probes label cell wall peptidoglycan in this genus at both the poles and sidewall. We sought to clarify the metabolic fates of these probes. Monopeptide incorporation was decreased by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa53559b80beb144a3f387b7bb0223f
https://elifesciences.org/articles/37243
https://elifesciences.org/articles/37243
Autor:
Benjamin M. Swarts, Hoong Chuin Lim, Yasu S. Morita, Emily S. Melzer, Taylor J. Fiolek, Jeffrey C Wagner, Sarah R. Rundell, Amol Arunrao Pohane, Alam García-Heredia, Caleb R. Carr, M. Sloan Siegrist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55882a8259271191d5e82a25de1651bd
https://doi.org/10.7554/elife.37243.039
https://doi.org/10.7554/elife.37243.039
Autor:
Taylor J. Fiolek, Anne W. Poston, Lisa M. Meints, Victoria M Mulholand, Jessica M. Groenevelt, Peter J. Woodruff, Alicyn I Stothard, Benjamin M. Swarts, David H Finocchietti
Trehalosamine (2-amino-2-deoxy-α,α-d-trehalose) is an aminoglycoside with antimicrobial activity against Mycobacterium tuberculosis, and it is also a versatile synthetic intermediate used to access imaging probes for mycobacteria. To overcome ineff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb04f18c9a28f9cd251c0def8150ba68
https://europepmc.org/articles/PMC6358420/
https://europepmc.org/articles/PMC6358420/