Identification of a de novo FOXP1 mutation and incidental discovery of inherited genetic variants contributing to a case of autism spectrum disorder and epilepsy

Autor: Kristy Jay, Amit Mitra, Taylor Harding, David Matthes, Brian Van Ness

Publikováno v: Molecular Genetics & Genomic Medicine, Vol 7, Iss 7, Pp n/a-n/a (2019)

Abstract Background Autism spectrum disorder is commonly co‐diagnosed intellectual disability, language disorder, anxiety, and epilepsy, however, symptom management is difficult due to the complex genetic nature of ASD. Methods We present a next‐

Externí odkaz: https://doaj.org/article/78f688a6dfa9469785481f7aaa28502a

Tumors defective in homologous recombination rely on oxidative metabolism: relevance to treatments with PARP inhibitors

Autor: Álvaro Lahiguera, Petra Hyroššová, Agnès Figueras, Diana Garzón, Roger Moreno, Vanessa Soto‐Cerrato, Iain McNeish, Violeta Serra, Conxi Lazaro, Pilar Barretina, Joan Brunet, Javier Menéndez, Xavier Matias‐Guiu, August Vidal, Alberto Villanueva, Barbie Taylor‐Harding, Hisashi Tanaka, Sandra Orsulic, Alexandra Junza, Oscar Yanes, Cristina Muñoz‐Pinedo, Luís Palomero, Miquel Àngel Pujana, José Carlos Perales, Francesc Viñals

Publikováno v: EMBO Molecular Medicine, Vol 12, Iss 6, Pp 1-23 (2020)

Abstract Mitochondrial metabolism and the generation of reactive oxygen species (ROS) contribute to the acquisition of DNA mutations and genomic instability in cancer. How genomic instability influences the metabolic capacity of cancer cells is never

Externí odkaz: https://doaj.org/article/85fc4cae15594bc18ccb7a3706bee159

A COL11A1-correlated pan-cancer gene signature of activated fibroblasts for the prioritization of therapeutic targets

Autor: Jia, Dongyu, Liu, Zhenqiu, Deng, Nan, Tan, Tuan Zea, Huang, Ruby Yun-Ju, Taylor-Harding, Barbie, Cheon, Dong-Joo, Lawrenson, Kate, Wiedemeyer, Wolf R., Walts, Ann E., Karlan, Beth Y., Orsulic, Sandra ^*

Publikováno v: In Cancer Letters 28 November 2016 382(2):203-214

VEGFR3 Inhibition Chemosensitizes Ovarian Cancer Stemlike Cells through Down-Regulation of BRCA1 and BRCA2

Autor: Lim, Jaeyoung, Yang, Kun, Taylor-Harding, Barbie, Wiedemeyer, W. Ruprecht, Buckanovich, Ronald J.

Publikováno v: In Neoplasia April 2014 16(4):343-353

Tumors defective in homologous recombination rely on oxidative metabolism: relevance to treatments with PARP inhibitors

Autor: Alberto Villanueva, Roger Moreno, Iain A. McNeish, Alexandra Junza, Vanessa Soto-Cerrato, Petra Hyroššová, Miquel Angel Pujana, August Vidal, Agnès Figueras, Xavier Matias-Guiu, Sandra Orsulic, Jose C. Perales, Conxi Lázaro, Barbie Taylor-Harding, Diana Garzón, Pilar Barretina, Francesc Viñals, Joan Brunet, Cristina Muñoz-Pinedo, Oscar Yanes, Álvaro Lahiguera, Hisashi Tanaka, Violeta Serra, Javier A. Menendez, Luis Palomero

Publikováno v: EMBO Molecular Medicine, 2020, vol. 12, núm. 6, p. e11217
Articles publicats (D-CM)
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EMBO molecular medicine, vol 12, iss 6
EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 12, Iss 6, Pp n/a-n/a (2020)
Scientia
Dipòsit Digital de la UB
Universidad de Barcelona

Mitochondrial metabolism and the generation of reactive oxygen species (ROS) contribute to the acquisition of DNA mutations and genomic instability in cancer. How genomic instability influences the metabolic capacity of cancer cells is nevertheless p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03f572d2b6b035d8b80a3d0d92695663
http://hdl.handle.net/10256/19523