Zobrazeno 1 - 10 of 18 pro vyhledávání: '"Taylor Follansbee"'
1
Akademický článek
A tactile twist: decoding the phenomena of mechanical itch and alloknesis
Autor: Taylor Follansbee, Xinzhong Dong
Publikováno v: Frontiers in Molecular Neuroscience, Vol 16 (2023)
Itch is a sensation in the skin which provokes the desire to scratch. In the past few decades there has been a significant elucidation of the immune and neural pathways which underly the sensation of itch. An interesting divergence in the itch pathwa
Externí odkaz: https://doaj.org/article/5770111e436e4df395dbbedc98352af9
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2
Akademický článek
Targeting Transient Receptor Potential (TRP) Channels, Mas-Related G-Protein-Coupled Receptors (Mrgprs), and Protease-Activated Receptors (PARs) to Relieve Itch
Autor: Merab G. Tsagareli, Taylor Follansbee, Mirela Iodi Carstens, Earl Carstens
Publikováno v: Pharmaceuticals, Vol 16, Iss 12, p 1707 (2023)
Itch (pruritus) is a sensation in the skin that provokes the desire to scratch. The sensation of itch is mediated through a subclass of primary afferent sensory neurons, termed pruriceptors, which express molecular receptors that are activated by itc
Externí odkaz: https://doaj.org/article/45e3a44bb5304cb4adf9d2e6df30d7e2
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3
Akademický článek
Inhibition of itch by neurokinin 1 receptor (Tacr1) -expressing ON cells in the rostral ventromedial medulla in mice
Autor: Taylor Follansbee, Dan Domocos, Eileen Nguyen, Amanda Nguyen, Aristea Bountouvas, Lauren Velasquez, Mirela Iodi Carstens, Keiko Takanami, Sarah E Ross, Earl Carstens
Publikováno v: eLife, Vol 11 (2022)
The rostral ventromedial medulla (RVM) is important in descending modulation of spinal nociceptive transmission, but it is unclear if the RVM also modulates spinal pruriceptive transmission. RVM ON cells are activated by noxious algesic and pruritic
Externí odkaz: https://doaj.org/article/baa6e8ba51f6423297cb12d62cfa5c9c
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4
Akademický článek
The Challenge of Basic Itch Research
Autor: Earl Carstens, Taylor Follansbee, Mirela Iodi Carstens
Publikováno v: Acta Dermato-Venereologica, Vol 100, Iss 2, p adv00023 (2020)
Basic mechanisms and pathways of itch signaling are reviewed, with an emphasis on the progress to date as well as remaining challenges in translating current knowledge to the clinical treatment of chronic itch. Recent studies reveal 3 subsets of prur
Externí odkaz: https://doaj.org/article/374cc1b257b343fd91d0db699111e801
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7
Cinnamaldehyde elicits itch behavior via TRPV1 and TRPV4 but not TRPA1
Autor: Dan Domocos, Taylor Follansbee, Amanda Nguyen, Tony Nguyen, Mirela Iodi Carstens, Earl Carstens
Publikováno v: Itch (Philadelphia, Pa.)
Introduction Cinnamaldehyde (CA) elicits itch sensation in humans. We investigated if CA elicits scratching behavior in mice and determined the roles for TRPV1, TRPA1, and TRPV4. Materials and methods Scratching behavior elicited by intradermal injec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be9b222367dea26e62b08a996e50f96d
https://pubmed.ncbi.nlm.nih.gov/34458578
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9
Neural Processing of Pain and Itch
Autor: Taylor Follansbee, Earl Carstens, Mirela Iodi Carstens
Pain is defined as “An unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage,” while itch can be defined as “an unpleasant sensation that evokes the desire to scratch.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::235f61a3198dd5ffaa01e52aede1e565
https://doi.org/10.1093/acrefore/9780190264086.013.83
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10
Transient receptor potential ankyrin 1 (TRPA1) positively regulates imiquimod-induced, psoriasiform dermal inflammation in mice
Autor: Mirela Iodi Carstens, Yan Zhou, Zhenrui Shi, Samuel T Hwang, Bo Wang, Dan Han, Dan Domocos, Taylor Follansbee, Sebastian Yu, Xuesong Wu, Earl Carstens
Publikováno v: Journal of cellular and molecular medicine, vol 23, iss 7
Journal of Cellular and Molecular Medicine
Transient receptor potential ankyrin 1 (TRPA1), a membrane protein ion channel, is known to mediate itch and pain in skin. The function of TRPA1, however, in psoriasiform dermatitis (PsD) is uncertain. Herein, we found that expression of TRPA1 is hig
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37cece611f5a59aa1aba61fcd601b74d
https://escholarship.org/uc/item/9mv3w32h
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