Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Taylor Feehley"'
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-13 (2023)
Abstract Background Modulating the epigenome has long been considered a potential opportunity for therapeutic intervention in numerous disease areas with several approved therapies marketed, primarily for cancer. Despite the overall promise of early
Externí odkaz:
https://doaj.org/article/dd268b606a184aa3bc3d159dafc08f24
Autor:
Katherine Nutsch, Jiani N. Chai, Teresa L. Ai, Emilie Russler-Germain, Taylor Feehley, Cathryn R. Nagler, Chyi-Song Hsieh
Publikováno v:
Cell Reports, Vol 17, Iss 1, Pp 206-220 (2016)
Commensal bacteria shape the colonic regulatory T (Treg) cell population required for intestinal tolerance. However, little is known about this process. Here, we use the transfer of naive commensal-reactive transgenic T cells expressing colonic Treg
Externí odkaz:
https://doaj.org/article/690c72d2b5f6466b998f8e2000e7dc66
Publikováno v:
Human Gene Therapy. Clinical Development
The era of gene therapy has begun. In recent years, potentially breakthrough datasets and rapidly expanding company pipelines have begun to overshadow the unfulfilled promise characteristic of the gene therapy sector in decades prior. One barometer f
Autor:
Sang Uk Seo, Xue Li, Matthew J. Hoostal, Cathryn R. Nagler, Merritt Gillilland, Eric C. Martens, Andrew T. Stefka, Shinji Fukuda, Thomas D. Wang, Yun Gi Kim, Kei Sakamoto, Gabriel Núñez, Thomas M. Schmidt, Taylor Feehley, Joseph M. Pickard, Naohiro Inohara, Nicholas A. Pudlo
Publikováno v:
Science. 356:315-319
Gut anaerobes protect against pathogen invasion Intestinal infections are a common problem for young animals. One explanation is that the protective gut microbiota is not fully established in infants. How the microbiota might protect against pathogen
Autor:
Andrew B. Janowski, Herbert W. Virgin, Harshad Ingle, Robyn S. Klein, Taylor Feehley, Megan T. Baldridge, H Dudley, David Wang
Publikováno v:
Journal of the Pediatric Infectious Diseases Society. 10:S14-S14
Background Since their original isolation from human stool samples in 1975, astroviruses have been assumed to be pathogens exclusive to the gastrointestinal tract. However, astroviruses have been recently identified from brain tissue of humans and ot
Autor:
Christine C. Yokoyama, Herbert W. Virgin, Lee-Yang Hsieh, Darren Kreamalmayer, Barry L. Hykes, Ya-Ting Wang, Paul M. Allen, Craig B. Wilen, Sanghyun Lee, Scott A. Handley, Menno van Lookeren Campagne, Jonathan R. Brestoff, Taylor Feehley, Chandni Desai, Michael R. McAllaster, Donna A. MacDuff, Ken Cadwell, Michael R. Howitt, Jessica A Neil, Robert C. Orchard, Dale R. Balce, Megan T. Baldridge, Christina A. Hickey
Aiding and abetting norovirus disease Norovirus is highly infectious and usually causes transient, acute disease. In some individuals, norovirus persists and is associated with inflammatory bowel disorders. While investigating the cell tropism for mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e8170e65297de6ae7e174599bce5019
https://europepmc.org/articles/PMC6039974/
https://europepmc.org/articles/PMC6039974/
Autor:
Evelyn Campbell, Taylor Feehley, Riyue Bao, Roberto Berni Canani, Cathryn R. Nagler, Catherine H. Plunkett, Lorella Paparo, Rita Nocerino, Rosita Aitoro, Jorge Andrade, Elliot Culleen, Sung Min Choi Hong, Pedro Belda-Ferre, Dionysios A. Antonopoulos
Publikováno v:
Nature medicine
There has been a striking generational increase in life-threatening food allergies in Westernized societies1,2. One hypothesis to explain this rising prevalence is that twenty-first century lifestyle practices, including misuse of antibiotics, dietar
Autor:
Cathryn R. Nagler, Taylor Feehley
Publikováno v:
Current Opinion in Immunology. 31:79-86
Food allergies are a growing public health concern. The rapidly increasing prevalence of allergic disease cannot be explained by genetic variation alone, suggesting a role for gene-by-environment interactions. The bacteria that colonize barrier surfa
Autor:
Prabhanshu Tripathi, Andrew T. Stefka, Eugene B. Chang, Dionysios A. Antonopoulos, Sarkis K. Mazmanian, Ju Qiu, Kathleen McCoy, Liang Zhou, Taylor Feehley, Severine Cao, Betty Theriault, Goo-Young Seo, Melissa Y Tjota, Cathryn R. Nagler, Yang Xin Fu
Publikováno v:
Proceedings of the National Academy of Sciences. 111:13145-13150
Environmentally induced alterations in the commensal microbiota have been implicated in the increasing prevalence of food allergy. We show here that sensitization to a food allergen is increased in mice that have been treated with antibiotics or are
Publikováno v:
FEBS Letters. 588:4258-4266
The prevalence of life-threatening anaphylactic responses to food is rising at an alarming rate. The emerging role of the gut microbiota in regulating food allergen sensitization may help explain this trend. The mechanisms by which commensal bacteria