Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Taylor Buley"'
Publikováno v:
Frontiers in Psychology, Vol 12 (2021)
This co-design study examined salutogenic potential of mobile virtual reality (VR) experiences as an alternative to participation in a community-based symphonic engagement program (B Sharp), previously found to benefit people with dementia (PWD) and
Externí odkaz:
https://doaj.org/article/5c0961655a2a45edbc022b79c18b732e
Autor:
Tara Lee Costich, Tyler Ellis, J. Edward Semple, Tomas Vojkovsky, Kevin Sill, Taylor Buley, Adam Carie, Brad Sullivan, Suzanne Bakewell
Publikováno v:
Pharmaceutical Nanotechnology. 4:3-15
Autor:
Taylor Buley, Adam Carie, J. Edward Semple, Bradford Sullivan, Richard Crouse, Suzanne Bakewell, Tara Lee Costich, Kevin Sill, Tyler Ellis
Publikováno v:
Journal of Drug Delivery
Journal of Drug Delivery, Vol 2016 (2016)
Journal of Drug Delivery, Vol 2016 (2016)
Epothilones have demonstrated promising potential for oncology applications but suffer from a narrow therapeutic window. Epothilone D stabilizes microtubules leading to apoptosis, is active against multidrug-resistant cells, and is efficacious in ani
Autor:
Jyothi Sethuraman, Suzanne Bakewell, Tara Lee Costich, Kevin Sill, J. Edward Semple, Tomas Vojkovsky, Adam Carie, Taylor Buley, Tyler Ellis
Publikováno v:
Molecular Cancer Research. 14:B22-B22
IT-141 is a formulation of SN-38 encapsulated in an iron-stabilized polymer micelle. SN-38 is the active metabolite of irinotecan (CPT-11) which in combination with 5-FU and leucovorin is first-line FDA approved therapy for metastatic colorectal canc
Autor:
Kevin Sill, J. Edward Semple, Tomas Vojkovsky, Suzanne Bakewell, Lauren Repp, Tyler Ellis, Rick Crouse, Tara Lee Costich, Adam Carie, Taylor Buley
Publikováno v:
Cancer Research. 76:1317-1317
Daunorubicin is an anthracycline family chemotherapeutic with a narrow therapeutic window. Employing our nanoparticle drug delivery platform we encapsulated daunorubicin non-covalently in the hydrophobic core of a polymer micelle (IT-143). IT-143 is
Autor:
Adam Carie, Kevin Sill, Suzanne Bakewell, J. Edward Semple, Bradford Sullivan, Rick Crouse, Jyothi Sethuraman, Tara Lee Costich, Tyler Ellis, Taylor Buley
Publikováno v:
Cancer Research. 76:1321-1321
IT-147 is a formulation of epothilone D encapsulated in a stabilized polymer micelle. Epothilones are a class of cytotoxic chemotherapeutics that induce apoptosis via microtubule stabilization. Epothilone D is a poor substrate for P-glycoprotein effl
Autor:
Kevin Sill, Tyler Ellis, Bradford Sullivan, Adam Carie, Suzanne Bakewell, Jyothi Sethuraman, Tara Lee Costich, J. Edward Semple, Taylor Buley, Tomas Vojkovsky
Publikováno v:
Cancer Research. 76:LB-190
Site-specific delivery of oncology drugs using nanoparticle technology has been a decades-long goal. IT-141 and IT-147 are polymer micelles that encapsulate (i.e. physically entrap without covalent bonds) hydrophobic chemotherapeutics in the core of