Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Taylor A. Murphree"'
Autor:
Kendra L. Francis, Hengqi B. Zheng, David L. Suskind, Taylor A. Murphree, Bao Anh Phan, Emily Quah, Aarun S. Hendrickson, Xisheng Zhou, Mason Nuding, Alexandra S. Hudson, Miklos Guttman, Gregory J. Morton, Michael W. Schwartz, Kimberly M. Alonge, Jarrad M. Scarlett
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract The intestinal extracellular matrix (ECM) helps maintain appropriate tissue barrier function and regulate host-microbial interactions. Chondroitin sulfate- and dermatan sulfate-glycosaminoglycans (CS/DS-GAGs) are integral components of the i
Externí odkaz:
https://doaj.org/article/079a8bfa3048479493c38f401f2d9cdd
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 329 (2023)
High concentrations of electrophilic lipid alkenals formed during oxidative stress are implicated in cytotoxicity and disease. However, low concentrations of alkenals are required to induce antioxidative stress responses. An established clearance pat
Externí odkaz:
https://doaj.org/article/e270b1016b824c80bcc9e3e37b0b99f2
Publikováno v:
Chemical Reviews. 122:7562-7623
Solution-phase hydrogen/deuterium exchange (HDX) coupled to mass spectrometry (MS) is a widespread tool for structural analysis across academia and the biopharmaceutical industry. By monitoring the exchangeability of backbone amide protons, HDX-MS ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f93007630dff5a196731a191aa8ecbe
https://doi.org/10.1021/acs.chemrev.1c00279
https://doi.org/10.1021/acs.chemrev.1c00279
Publikováno v:
J Am Soc Mass Spectrom
Carbohydrates are among the most complex class of biomolecules and even subtle variations in their structures are attributed to diverse biological function. Mass spectrometry has been essential for large scale glycomics and glycoproteomics studies, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::250f8d84e03970400b8ba32f30ca6aa6
https://doi.org/10.1021/jasms.0c00440
https://doi.org/10.1021/jasms.0c00440
Publikováno v:
Anal Chem
Hydrogen deuterium exchange mass spectrometry (HDX-MS) is a powerful tool for protein structure analysis that is well suited for biotherapeutic development and characterization. Because HDX is strongly dependent on solution conditions; even small var
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56d5337b51a3999e98671c01b68f997a
https://doi.org/10.1021/acs.analchem.0c01328
https://doi.org/10.1021/acs.analchem.0c01328
Publikováno v:
Journal of the American Society for Mass Spectrometry. 31(9)
Although most peptide bonds in proteins exist in the trans configuration, when cis peptide bonds do occur, they can have major impact on protein structure and function. The rapid identification of cis peptide bonds is therefore an important task. Pep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a00ddd6cda01218dfb0c252f33774d
https://pubmed.ncbi.nlm.nih.gov/32808771
https://pubmed.ncbi.nlm.nih.gov/32808771
Autor:
Joshua R. Hansen, Lindsey N. Anderson, Christoph Grundner, Erika L. Flannery, Neil Fleck, Richard D. Smith, Matthew Fishbaugher, Bobbie-Jo M. Webb-Robertson, Andrew Frando, Corrie Ortega, Aaron T. Wright, Taylor A. Murphree, Stefan H. I. Kappe
Publikováno v:
Molecular & Cellular Proteomics. 17:111-120
Effective malaria control and elimination in hyperendemic areas of the world will require treatment of the Plasmodium falciparum (Pf) blood stage that causes disease as well as the gametocyte stage that is required for transmission from humans to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e89835c9c915ce412e60055e749f88e3
https://doi.org/10.1074/mcp.ra117.000088
https://doi.org/10.1074/mcp.ra117.000088
De novo synthesis of alkyne substituted tryptophans as chemical probes for protein profiling studies
Autor:
Mark E. Bowden, Reji N. Nair, Stephen R. Lindemann, Joshua J. Rosnow, Aaron T. Wright, Taylor A. Murphree
Publikováno v:
Organic Chemistry Frontiers. 4:495-499
De novo synthesis of alkynalted tryptophan moieties as chemical probes for protein profilling studies, via an unexpected synthesis of Michael acceptor 12 is reported. Friedel Craft's alkylation of 12 and alkyne substituted indoles gave alkynalated tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::851d59a8e00343483cce6ef50c57c3a5
https://doi.org/10.1039/c6qo00819d
https://doi.org/10.1039/c6qo00819d
Autor:
William A. Banks, Dale Whittington, Kimberly M. Alonge, Aric F. Logsdon, Miklos Guttman, C. Dirk Keene, J. Scott Edgar, Michael W. Schwartz, Taylor A Murphree
Publikováno v:
Glycobiology
Chondroitin sulfates (CS) are long, negatively charged, unbranched glycosaminoglycan (GAG) chains attached to CS-proteoglycan (CSPG) core proteins that comprise the glycan component in both loose interstitial extracellular matrices (ECMs) and in rigi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f867773293b9f30ebb39c0bd818ccee4
https://pubmed.ncbi.nlm.nih.gov/31361007
https://pubmed.ncbi.nlm.nih.gov/31361007
Autor:
Ethan G. Stoddard, Jordan N. Smith, Charles Ansong, James P. Carson, Natalie C. Sadler, Cecilia M Ljungberg, Aaron T. Wright, Taylor A. Murphree, Anil K. Shukla, Regan F Volk
Publikováno v:
Journal of proteome research. 17(8)
Lung diseases and disorders are a leading cause of death among infants. Many of these diseases and disorders are caused by premature birth and underdeveloped lungs. In addition to developmentally related disorders, the lungs are exposed to a variety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd35718058cd3f014a9cddbd98d54dc6
https://pubmed.ncbi.nlm.nih.gov/29972024
https://pubmed.ncbi.nlm.nih.gov/29972024