The cells are all-right: Regulation of the Lefty genes by separate enhancers in mouse embryonic stem cells.

Autor: Taylor, Tiegh¹ (AUTHOR), Zhu, Hongyu Vicky¹ (AUTHOR), Moorthy, Sakthi D.¹ (AUTHOR), Khader, Nawrah¹ (AUTHOR), Mitchell, Jennifer A.^1,2 (AUTHOR) ja.mitchell@utoronto.ca

Publikováno v: PLoS Genetics. 12/13/2024, Vol. 20 Issue 12, p1-19. 19p.

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Luman Potentially Regulates Metabolism Through Modulation of the Hypothalamic-Pituitary-Adrenal Axis

Autor: Taylor, Tiegh

Luman is an endoplasmic reticulum associated transmembrane protein which when activated, alleviates endoplasmic reticulum stress. Recently, Luman has been found to play a key role in glucocorticoid signaling which modulates the whole-body stress resp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______453::96790784009ad00bb3005b86f0d6146f
https://hdl.handle.net/10214/14605

Transcription processes compete with loop extrusion to homogenize promoter and enhancer dynamics.

Autor: Platania A; Department of Functional Genomics and Cancer, Institute of Genetics and Molecular and Cellular Biology (IGBMC), UMR7104, Centre National de la Recherche Scientifique, U1258, Institut National de la Santé et de la Recherche Médicale, University of Strasbourg, 6704 Illkirch, France., Erb C; Department of Functional Genomics and Cancer, Institute of Genetics and Molecular and Cellular Biology (IGBMC), UMR7104, Centre National de la Recherche Scientifique, U1258, Institut National de la Santé et de la Recherche Médicale, University of Strasbourg, 6704 Illkirch, France., Barbieri M; Translational Epigenetics Group, Institute of Pathology, University Medical Centre Göttingen, Göttingen, Germany., Molcrette B; Department of Functional Genomics and Cancer, Institute of Genetics and Molecular and Cellular Biology (IGBMC), UMR7104, Centre National de la Recherche Scientifique, U1258, Institut National de la Santé et de la Recherche Médicale, University of Strasbourg, 6704 Illkirch, France., Grandgirard E; Department of Functional Genomics and Cancer, Institute of Genetics and Molecular and Cellular Biology (IGBMC), UMR7104, Centre National de la Recherche Scientifique, U1258, Institut National de la Santé et de la Recherche Médicale, University of Strasbourg, 6704 Illkirch, France., de Kort MAC; Division of Gene Regulation, the Netherlands Cancer Institute, Oncode Institute, 1066CX Amsterdam, Netherlands., Pomp W; Division of Gene Regulation, the Netherlands Cancer Institute, Oncode Institute, 1066CX Amsterdam, Netherlands., Meaburn K; Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Brighton, UK., Taylor T; Department of Cell and Systems Biology, University of Toronto, Toronto, Ontario M55 3G5, Canada., Shchuka VM; Department of Cell and Systems Biology, University of Toronto, Toronto, Ontario M55 3G5, Canada., Kocanova S; Molecular Cellular and Developmental Biology Unit (MCD), Centre de Biologie Integrative (CBI), University of Toulouse Paul Sabatier, CNRS, 31062 Toulouse, France., Nazarova M; Department of Functional Genomics and Cancer, Institute of Genetics and Molecular and Cellular Biology (IGBMC), UMR7104, Centre National de la Recherche Scientifique, U1258, Institut National de la Santé et de la Recherche Médicale, University of Strasbourg, 6704 Illkirch, France., Oliveira GM; Department of Functional Genomics and Cancer, Institute of Genetics and Molecular and Cellular Biology (IGBMC), UMR7104, Centre National de la Recherche Scientifique, U1258, Institut National de la Santé et de la Recherche Médicale, University of Strasbourg, 6704 Illkirch, France., Mitchell JA; Department of Cell and Systems Biology, University of Toronto, Toronto, Ontario M55 3G5, Canada., Soutoglou E; Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Brighton, UK., Lenstra TL; Division of Gene Regulation, the Netherlands Cancer Institute, Oncode Institute, 1066CX Amsterdam, Netherlands., Molina N; Department of Functional Genomics and Cancer, Institute of Genetics and Molecular and Cellular Biology (IGBMC), UMR7104, Centre National de la Recherche Scientifique, U1258, Institut National de la Santé et de la Recherche Médicale, University of Strasbourg, 6704 Illkirch, France., Papantonis A; Translational Epigenetics Group, Institute of Pathology, University Medical Centre Göttingen, Göttingen, Germany., Bystricky K; Molecular Cellular and Developmental Biology Unit (MCD), Centre de Biologie Integrative (CBI), University of Toulouse Paul Sabatier, CNRS, 31062 Toulouse, France.; Institut Universitaire de France (IUF), 75005 Paris, France., Sexton T; Department of Functional Genomics and Cancer, Institute of Genetics and Molecular and Cellular Biology (IGBMC), UMR7104, Centre National de la Recherche Scientifique, U1258, Institut National de la Santé et de la Recherche Médicale, University of Strasbourg, 6704 Illkirch, France.

Publikováno v: Science advances [Sci Adv] 2024 Dec 13; Vol. 10 (50), pp. eadq0987. Date of Electronic Publication: 2024 Dec 13.

Competition between transcription and loop extrusion modulates promoter and enhancer dynamics.

Autor: Platania A; Department of Functional Genomics and Cancer, Institute of Genetics and Molecular and Cellular Biology (IGBMC), UMR7104, Centre National de la Recherche Scientifique, U1258, Institut National de la Santé et de la Recherche Médicale, University of Strasbourg, 6704 Illkirch, France., Erb C; Department of Functional Genomics and Cancer, Institute of Genetics and Molecular and Cellular Biology (IGBMC), UMR7104, Centre National de la Recherche Scientifique, U1258, Institut National de la Santé et de la Recherche Médicale, University of Strasbourg, 6704 Illkirch, France., Barbieri M; Translational Epigenetics Group, Institute of Pathology, University Medical Centre Göttingen, Göttingen, Germany., Molcrette B; Department of Functional Genomics and Cancer, Institute of Genetics and Molecular and Cellular Biology (IGBMC), UMR7104, Centre National de la Recherche Scientifique, U1258, Institut National de la Santé et de la Recherche Médicale, University of Strasbourg, 6704 Illkirch, France., Grandgirard E; Department of Functional Genomics and Cancer, Institute of Genetics and Molecular and Cellular Biology (IGBMC), UMR7104, Centre National de la Recherche Scientifique, U1258, Institut National de la Santé et de la Recherche Médicale, University of Strasbourg, 6704 Illkirch, France., de Kort MA; Division of Gene Regulation, the Netherlands Cancer Institute, Oncode Institute, 1066CX Amsterdam, the Netherlands., Meaburn K; Genome Damage and Stability Centre, Sussex University, School of Life Sciences, University of Sussex, Brighton, UK., Taylor T; Department of Cell and Systems Biology, University of Toronto, Toronto, Ontario M55 3G5, Canada., Shchuka VM; Department of Cell and Systems Biology, University of Toronto, Toronto, Ontario M55 3G5, Canada., Kocanova S; Molecular Cellular and Developmental Biology unit (MCD), Centre de Biologie Integrative (CBI) University of Toulouse Paul Sabatier, CNRS, 31062 Toulouse, France., Oliveira GM; Department of Functional Genomics and Cancer, Institute of Genetics and Molecular and Cellular Biology (IGBMC), UMR7104, Centre National de la Recherche Scientifique, U1258, Institut National de la Santé et de la Recherche Médicale, University of Strasbourg, 6704 Illkirch, France., Mitchell JA; Department of Cell and Systems Biology, University of Toronto, Toronto, Ontario M55 3G5, Canada., Soutoglou E; Genome Damage and Stability Centre, Sussex University, School of Life Sciences, University of Sussex, Brighton, UK., Lenstra TL; Division of Gene Regulation, the Netherlands Cancer Institute, Oncode Institute, 1066CX Amsterdam, the Netherlands., Molina N; Department of Functional Genomics and Cancer, Institute of Genetics and Molecular and Cellular Biology (IGBMC), UMR7104, Centre National de la Recherche Scientifique, U1258, Institut National de la Santé et de la Recherche Médicale, University of Strasbourg, 6704 Illkirch, France., Papantonis A; Translational Epigenetics Group, Institute of Pathology, University Medical Centre Göttingen, Göttingen, Germany., Bystricky K; Molecular Cellular and Developmental Biology unit (MCD), Centre de Biologie Integrative (CBI) University of Toulouse Paul Sabatier, CNRS, 31062 Toulouse, France.; Institut Universitaire de France (IUF)., Sexton T; Department of Functional Genomics and Cancer, Institute of Genetics and Molecular and Cellular Biology (IGBMC), UMR7104, Centre National de la Recherche Scientifique, U1258, Institut National de la Santé et de la Recherche Médicale, University of Strasbourg, 6704 Illkirch, France.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Apr 26. Date of Electronic Publication: 2023 Apr 26.