Zobrazeno 1 - 1
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pro vyhledávání: '"Taylie Sargent"'
Autor:
Tara L. Spires-Jones, Claudia Cannavo, Bradley T. Hyman, Taylie Sargent, Rebecca A. Betensky, Jacob Aaron Klickstein, Kishore V. Kuchibhotla, Eloise Hudry, Alona Muzikansky, Lauren Wrobleski, Allyson D. Roe, David Urick, Steven S. Hou, Rosemary J. Jackson, Sheetal Gandhi
Publikováno v:
Life Science Alliance
Hudry, E, Klickstein, J, Cannavo, C, Jackson, R, Muzikansky, A, Gandhi, S, Urick, D, Sargent, T, Wrobleski, L, Roe, A D, Hou, S S, Kuchibhotla, K V, Betensky, R A, Spires-Jones, T & Hyman, B T 2019, ' Opposing Roles of apolipoprotein E in aging and neurodegeneration ', Life Science Alliance, vol. 2, no. 1 . https://doi.org/10.26508/lsa.201900325
Hudry, E, Klickstein, J, Cannavo, C, Jackson, R, Muzikansky, A, Gandhi, S, Urick, D, Sargent, T, Wrobleski, L, Roe, A D, Hou, S S, Kuchibhotla, K V, Betensky, R A, Spires-Jones, T & Hyman, B T 2019, ' Opposing Roles of apolipoprotein E in aging and neurodegeneration ', Life Science Alliance, vol. 2, no. 1 . https://doi.org/10.26508/lsa.201900325
This study investigates how APOE modulates neuronal function integrity during normal aging and in the context of amyloidosis. This work demonstrates that APOE is a necessary partner of Aβ-dependent neuronal dysfunction and synaptotoxicity but also p