Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Tayleur D. White"'
Autor:
Tayleur D. White, Abdulaziz Almutairi, Ying Gai-Tusing, Daniel J. Stephenson, Benjamin D. Stephenson, Charles E. Chalfant, Xiaoyong Lei, Brian Lu, Bruce D. Hammock, Teresa P. DiLorenzo, Sasanka Ramanadham
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionWe reported that Ca2+-independent phospholipase A2β (iPLA2β)–derived lipids (iDLs) contribute to type 1 diabetes (T1D) onset. As CD4+ and CD8+ T cells are critical in promoting β-cell death, we tested the hypothesis that iDL signalin
Externí odkaz:
https://doaj.org/article/588f970bbb8d45fbb26e60d608d19390
Autor:
Alexander J. Nelson, Daniel J. Stephenson, Christopher L. Cardona, Xiaoyong Lei, Abdulaziz Almutairi, Tayleur D. White, Ying G. Tusing, Margaret A. Park, Suzanne E. Barbour, Charles E. Chalfant, Sasanka Ramanadham
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 2, Pp 143-158 (2020)
Phospholipases A2 (PLA2s) catalyze hydrolysis of the sn-2 substituent from glycerophospholipids to yield a free fatty acid (i.e., arachidonic acid), which can be metabolized to pro- or anti-inflammatory eicosanoids. Macrophages modulate inflammatory
Externí odkaz:
https://doaj.org/article/6547dd63283e4d0aa77cb2128df44b45
Publikováno v:
Biomolecules, Vol 11, Iss 4, p 577 (2021)
The Ca2+-independent phospholipase A2β (iPLA2β) is a member of the PLA2 family that has been proposed to have roles in multiple biological processes including membrane remodeling, cell proliferation, bone formation, male fertility, cell death, and
Externí odkaz:
https://doaj.org/article/f07516879d81409a83bd4ab432ebfe08
Autor:
Suzanne E. Barbour, Tayleur D. White, Ying Gai Tusing, Christopher L. Cardona, Xiaoyong Lei, Sasanka Ramanadham, Abdulaziz Almutairi, Daniel J. Stephenson, Charles E. Chalfant, Margaret A. Park, Alexander J. Nelson
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 2, Pp 143-158 (2020)
Phospholipases A2 (PLA2s) catalyze hydrolysis of the sn-2 substituent from glycerophospholipids to yield a free fatty acid (i.e., arachidonic acid), which can be metabolized to pro- or anti-inflammatory eicosanoids. Macrophages modulate inflammatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3620e25eb6ce0475a446c86484938b6d
http://www.sciencedirect.com/science/article/pii/S0022227520435333
http://www.sciencedirect.com/science/article/pii/S0022227520435333
Publikováno v:
Diabetes. 70
Type 1 diabetes (T1D) is a T-cell mediated autoimmune disease characterized by the destruction of insulin-producing pancreatic islet β-cells. An understudied area is the role lipid signaling plays in this process. We find that the Ca2+-independent p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3f21722a06160644674f4012b8bc115
https://doi.org/10.2337/db21-112-or
https://doi.org/10.2337/db21-112-or
iPLA2β and its role in male fertility, neurological disorders, metabolic disorders, and inflammation
Publikováno v:
Biochim Biophys Acta Mol Cell Biol Lipids
The Ca(2+)-independent phospholipases, designated as group VI iPLA(2)s, also referred to as PNPLAs due to their shared homology with patatin, include the β, γ, δ, ε, ζ, and η forms of the enzyme. The iPLA(2)s are ubiquitously expressed, share a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a86f6993421221a70fd167232906738b
https://doi.org/10.1016/j.bbalip.2018.10.010
https://doi.org/10.1016/j.bbalip.2018.10.010
Publikováno v:
Biomolecules, Vol 11, Iss 577, p 577 (2021)
Biomolecules
Biomolecules
The Ca2+-independent phospholipase A2β (iPLA2β) is a member of the PLA2 family that has been proposed to have roles in multiple biological processes including membrane remodeling, cell proliferation, bone formation, male fertility, cell death, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbf6128c259ab848886b7907f3b44ad3
https://pubmed.ncbi.nlm.nih.gov/33920898
https://pubmed.ncbi.nlm.nih.gov/33920898
Publikováno v:
Diabetes. 69
Type 1 diabetes (T1D) is a T-cell mediated autoimmune disease characterized by the destruction of insulin-producing pancreatic islet β-cells. An understudied area is the role of lipid signaling. We find that the Ca2+-independent phospholipase A2β (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9b4605b4276071a1a0285aea50c1f8f
https://doi.org/10.2337/db20-1667-p
https://doi.org/10.2337/db20-1667-p
Autor:
Alexander J, Nelson, Daniel J, Stephenson, Christopher L, Cardona, Xiaoyong, Lei, Abdulaziz, Almutairi, Tayleur D, White, Ying G, Tusing, Margaret A, Park, Suzanne E, Barbour, Charles E, Chalfant, Sasanka, Ramanadham
Publikováno v:
J Lipid Res
Phospholipases A(2) (PLA(2)s) catalyze hydrolysis of the sn-2 substituent from glycerophospholipids to yield a free fatty acid (i.e., arachidonic acid), which can be metabolized to pro- or anti-inflammatory eicosanoids. Macrophages modulate inflammat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d2a313f806c066426f4f583a5cc3a22e
https://pubmed.ncbi.nlm.nih.gov/31818877
https://pubmed.ncbi.nlm.nih.gov/31818877
Publikováno v:
Diabetes. 68
Type 1 diabetes (T1D) is the result of autoimmune-mediated destruction of pancreatic islet β-cells by activated autoreactive inflammatory cells, effecting insulin production from β-cells. The Ca2+-independent phospholipase A2β(iPLA2β), a member o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54fff6c9d2adf0d0e5da5e6c59d3f72b
https://doi.org/10.2337/db19-1745-p
https://doi.org/10.2337/db19-1745-p