Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Taygun C Uzuneser"'
Autor:
Marta De Felice, Hanna J. Szkudlarek, Taygun C. Uzuneser, Mar Rodríguez-Ruiz, Mohammed H. Sarikahya, Mathusha Pusparajah, Juan Pablo Galindo Lazo, Shawn N. Whitehead, Ken K.-C. Yeung, Walter J. Rushlow, Steven R. Laviolette
Publikováno v:
Biological Psychiatry Global Open Science, Vol 4, Iss 6, Pp 100361- (2024)
Background: Exposure to Δ9-tetrahydrocannabinol (THC) is an established risk factor for later-life neuropsychiatric vulnerability, including mood- and anxiety-related symptoms. The psychotropic effects of THC on affect and anxiogenic behavioral phen
Externí odkaz:
https://doaj.org/article/27928f2b63ef418698a78cd70f62b509
Autor:
Taygun C Uzuneser, Hanna J Szkudlarek, Matthew J Jones, Mina G Nashed, Timothy Clement, Hehe Wang, Iwao Ojima, Walter J Rushlow, Steven R Laviolette
Publikováno v:
Cereb Cortex
The endocannabinoid (eCB) system represents a promising neurobiological target for novel anxiolytic pharmacotherapies. Previous clinical and preclinical evidence has revealed that genetic and/or pharmacological manipulations altering eCB signaling mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7250e6f9f617a1076aa74df69e3812a6
https://doi.org/10.1093/cercor/bhac220
https://doi.org/10.1093/cercor/bhac220
Autor:
Taygun C. Uzuneser, Jil Speidel, Georgios Kogias, An-Li Wang, Maria A. de Souza Silva, Joseph P. Huston, Iulia Zoicas, Stephan von Hörsten, Johannes Kornhuber, Carsten Korth, Christian P. Müller
Publikováno v:
Frontiers in Psychiatry, Vol 10 (2019)
Synaptic pruning is a critical refinement step during neurodevelopment, and schizophrenia has been associated with overpruning of cortical dendritic spines. Both human studies and animal models implicate disrupted-in-schizophrenia 1 (DISC1) gene as a
Externí odkaz:
https://doaj.org/article/b75556aa7edd4ceebdd96aa1db385e7b
Autor:
Eva-Maria Weiss, Taygun C Uzuneser, Jonas Kaindl, Jan Hellmann, Stefan Löber, Teja W. Grömer, Christian P. Müller, Jana Dahlmanns, Christian Alzheimer, Harald Hübner, Peter Gmeiner, Liubov S. Kalinichenko, Davide Amato, Johannes Kornhuber
Publikováno v:
Journal of Psychopharmacology (Oxford, England)
Background:The therapeutic effects of antipsychotic drugs (APDs) are mainly attributed to their postsynaptic inhibitory functions on the dopamine D2 receptor, which, however, cannot explain the delayed onset of full therapeutic efficacy. It was previ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43b6afc884d1cc306bf1ee5291b99e1d
http://europepmc.org/articles/PMC7770212
http://europepmc.org/articles/PMC7770212
Autor:
Ekrem Dere, Johannes Kornhuber, Teja W. Grömer, Christian P. Müller, Taygun C. Uzuneser, Stephan von Hörsten, Magnus Schindehütte
Publikováno v:
European Neuropsychopharmacology. 28:1382-1393
Schizophrenic patients suffer from various disruptions in their psyche, mood and cognition, most of which cannot be effectively treated with the available antipsychotic drugs. Some dimensions of the schizophrenia syndrome in man can be mimicked in an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6896c30a97d6ec381fa0f0241fc23556
https://doi.org/10.1016/j.euroneuro.2018.09.005
https://doi.org/10.1016/j.euroneuro.2018.09.005
Publikováno v:
Neuropsychopharmacology. 43:1651-1659
The relief from an aversive event is rewarding. Since organisms are able to learn which environmental cues can cease an aversive event, relief learning helps to better cope with future aversive events. Literature data suggest that relief learning is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33d3f9756230724afef66bc2236a9207
https://doi.org/10.1038/s41386-018-0020-1
https://doi.org/10.1038/s41386-018-0020-1
Autor:
Bianca Plouffe, Peter Gmeiner, Christian P. Müller, Marika Skultety, Taygun C. Uzuneser, Christian Alzheimer, Dorothee Möller, Kristina Friedland, Tobias Huth, Ashutosh Banerjee, Michel Bouvier, Harald Hübner
Publikováno v:
Journal of Medicinal Chemistry. 60:2908-2929
1,4-Disubstituted aromatic piperazines are privileged structural motifs recognized by aminergic G protein-coupled receptors. Connection of a lipophilic moiety to the arylpiperazine core by an appropriate linker represents a promising concept to incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::101505eacafdfe15754c6cb279fcbabd
https://doi.org/10.1021/acs.jmedchem.6b01857
https://doi.org/10.1021/acs.jmedchem.6b01857
Autor:
Taygun C, Uzuneser, Jil, Speidel, Georgios, Kogias, An-Li, Wang, Maria A, de Souza Silva, Joseph P, Huston, Iulia, Zoicas, Stephan, von Hörsten, Johannes, Kornhuber, Carsten, Korth, Christian P, Müller
Publikováno v:
Frontiers in Psychiatry, Vol 10 (2019)
Synaptic pruning is a critical refinement step during neurodevelopment, and schizophrenia has been associated with overpruning of cortical dendritic spines. Both human studies and animal models implicate disrupted-in-schizophrenia 1 (DISC1) gene as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f1485983276984363328e10eef9fb740
https://opus4.kobv.de/opus4-fau/files/12741/fpsyt-10-00222-g007.tif
https://opus4.kobv.de/opus4-fau/files/12741/fpsyt-10-00222-g007.tif
Autor:
Taygun C. Uzuneser, Markus Fendt
Publikováno v:
Behavioural Brain Research. 393:112799
Stimuli that are either presented directly after or explicitly unpaired to an aversive event can be associated with the relief or absence of the aversive event. Such stimuli then become conditioned stimuli (CS) for relief or safety, respectively, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e6083399d83509f424d3de78527bb6c
https://doi.org/10.1016/j.bbr.2020.112799
https://doi.org/10.1016/j.bbr.2020.112799
Autor:
Johannes Kornhuber, Teja W. Grömer, Stefan Löber, Taygun C. Uzuneser, Jan Hellmann, Jana Katharina Dahlmanns, Christian Alzheimer, Harald Hübner, Peter Gmeiner, Christian Müller, Liubov S. Kalinichenko, Eva-Maria Weiss
Publikováno v:
Schizophrenia Bulletin
Background The therapeutic effects of antipsychotic drugs (APDs) are mainly attributed to their post synaptic inhibitory functions on the dopamine D2 receptor, which however, cannot explain the delayed onset of full therapeutic efficacy. It was previ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb1c9b8991f36103555d9559fd3b0d22
http://europepmc.org/articles/PMC7234311
http://europepmc.org/articles/PMC7234311