Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Taybor W. Parker"'
Publikováno v:
Cancers, Vol 12, Iss 2114, p 2114 (2020)
Cancers
Volume 12
Issue 8
Cancers
Volume 12
Issue 8
The Wnt/&beta
catenin signaling pathway is deregulated in nearly all colorectal cancers (CRCs), predominantly through mutation of the tumor suppressor Adenomatous Polyposis Coli (APC). APC mutation is thought to allow a &ldquo
just-right&rd
catenin signaling pathway is deregulated in nearly all colorectal cancers (CRCs), predominantly through mutation of the tumor suppressor Adenomatous Polyposis Coli (APC). APC mutation is thought to allow a &ldquo
just-right&rd
Autor:
Taybor W. Parker, Kristi L. Neufeld
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Wnt/β-catenin signaling is essential for intestinal homeostasis and is aberrantly activated in most colorectal cancers (CRC) through mutation of the tumor suppressor Adenomatous Polyposis Coli (APC). APC is an essential component of a cytoplasmic pr
Autor:
Kristi L. Neufeld, Taybor W. Parker
Publikováno v:
The FASEB Journal. 34:1-1
Wnt/β-catenin signaling is essential for intestinal homeostasis and is aberrantly activated in most colorectal cancers (CRC) through mutation of the tumor suppressor Adenomatous Polyposis Coli (APC). APC is an essential component of a cytoplasmic pr
Autor:
Taybor W. Parker, James M. Amos-Landgraf, Marcia L. Hart, Elizabeth C. Bryda, Susheel Bhanu Busi, Angela Goerndt, Kevin B. Jones, Sarah A. Hansen
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 10, Pp 1139-1146 (2016)
Disease Models & Mechanisms
Disease Models & Mechanisms
Somatic mutations in the Tp53 tumor suppressor gene are the most commonly seen genetic alterations in cancer, and germline mutations in Tp53 predispose individuals to a variety of early-onset cancers. Development of appropriate translational animal m
Autor:
James M. Amos-Landgraf, Takashi Kuramoto, Kazuto Yoshimi, William F. Dove, Marcia L. Hart, Madeline R Ford, Taybor W. Parker, Amy A. Irving, Linda Clipson
Publikováno v:
Disease Models & Mechanisms
Disease Models & Mechanisms, Vol 7, Iss 11, Pp 1215-1225 (2014)
Disease Models & Mechanisms, Vol 7, Iss 11, Pp 1215-1225 (2014)
Prior to the advent of genetic engineering in the mouse, the rat was the model of choice for investigating the etiology of cancer. Now, recent advances in the manipulation of the rat genome, combined with a growing recognition of the physiological di
Autor:
Elizabeth C. Bryda, Aaron C. Ericsson, Miriam A. Hankins, Susheel Bhanu Busi, Taybor W. Parker, Craig L. Franklin, Rebecca Schehr, James M. Amos-Landgraf, Marina R. McCoy
Publikováno v:
Cancer Research. 75:2880-2880
To understand the impact of differences in complex microbiota on colon cancer susceptibility, we utilized the Pirc (Polyposis In Rat Colon) model of familial human colon cancer to correlate the longitudinal changes of the gut microbiota with early ad