Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Taxuspine"'
Autor:
Daniele Castagnolo, Giorgio Maccari, Stanislava I. Avramova, Maurizio Botta, Gianpietro Sgaragli, Lorenzo Contemori, Annalisa Neri
Publikováno v:
ACS Medicinal Chemistry Letters. 1:416-421
Three simplified "non-natural" natural taxanes, related to taxuspine X, were synthetized and assayed as P-glycoprotein (P-gp) inhibitors. One of them (6) proved to be a very efficient P-gp inhibitor with an IC50 = 7.2 × 10(-6) M. In addition, to rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f44dff6eb9e53b72cdd2f497f76e6d16
https://doi.org/10.1021/ml100118k
https://doi.org/10.1021/ml100118k
Publikováno v:
Phytochemical Analysis. 20:246-252
Introduction The study of taxanes is a hot topic worldwide because of their potential activity against cancer. Analysis of taxanes in extracts of various Taxus species is generally achieved using HPLC. Objective The aim of the current work was to ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14f93b14120c1cc2b701922552b57339
https://doi.org/10.1002/pca.1121
https://doi.org/10.1002/pca.1121
Autor:
Gianluca Giorgi, Marco Radi, Daniela Alderighi, Gianpietro Sgaragli, Stanislava I. Avramova, Elena Galletti, Chiara Ghiron, Federico Corelli, Michela L. Renzulli, Maurizio Botta
Publikováno v:
ChemMedChem. 3(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebd4bb6b630ceb6f957f8e5b7e649b0c
https://pubmed.ncbi.nlm.nih.gov/18232049
https://pubmed.ncbi.nlm.nih.gov/18232049
Autor:
Hideyuki Shigemori, Zhe-Sheng Chen, Jun'ichi Kobayashi, Shin-ichi Akiyama, Mikihiko Naito, Takashi Tsuruo, Hirokazu Hosoyama
Publikováno v:
Japanese Journal of Cancer Research : Gann
Some non-taxol-type taxoids having neither an oxetane ring at C-4 and C-5 nor an N-acylphenyl-isoserine group at C-13, such as taxuspine C, 2'-desacetoxyaustrospicatine, and 2-desacetoxytaxinine J, which were isolated from the Japanese yew Taxus cusp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4d9369217273700406ea60dae3cce3c
https://doi.org/10.1111/j.1349-7006.2000.tb00993.x
https://doi.org/10.1111/j.1349-7006.2000.tb00993.x
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 64:894-898
Four novel taxane diterpenes were isolated from the needles of the Japanese yew, Taxus cuspidata. Their structures were established as 1-hydroxy taxuspine C, 2α,7β,9α, 10β,13α-pentaacetoxy-5α-cinnamoyloxy-4β,20-epoxy- taxa-11-en-1β-ol, 2α,9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aceb63e0bf772e92459b1db26754063
https://doi.org/10.1271/bbb.64.894
https://doi.org/10.1271/bbb.64.894
Three New Bicyclic Taxane Diterpenoids from the Needles of Japanese Yew,Taxus cuspidataSieb. Et Zucc
Publikováno v:
Journal of Asian Natural Products Research. 2:63-70
Three new bicyclic taxane diterpenes were isolated from the needles of the Japanese yew, Taxus cuspidata Sieb. et Zucc. Their structures were established to be 7,9,10,13-tetraacetoxy-5-cinna-moyloxy-4-hydroxy-methyl-8,12,15,15-tetramethyl-bicyclo[9.3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e27f4e9b8edea4068d97ca562d19d4f5
https://doi.org/10.1080/10286029908039893
https://doi.org/10.1080/10286029908039893
Publikováno v:
Journal of Natural Products. 61:1437-1440
Three novel (1-3) and five known bicyclic 3,8-secotaxane diterpenoids were isolated from the needles of the Chinese yew, Taxus chinensis var. mairei. The structures of the new compounds were established, respectively, as (3E,7E)-2alpha,10beta, 13alph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5721204a21cd227b9cc56971bb55ca2
https://doi.org/10.1021/np980213q
https://doi.org/10.1021/np980213q
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :417-422
Selective O-deacylations of taxinine 1a, readily available from needles of Taxus cuspidata, at C-2, C-5 and C-9,10 have been accomplished by treatment with barium hydroxide octahydrate, sodium bis(2-methoxyethoxy)aluminium hydride (Red-Al®) or diiso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::354d1698132f88689c5ebdf8c1d98109
https://doi.org/10.1039/a707146i
https://doi.org/10.1039/a707146i
Publikováno v:
Natural Product Letters. 10:165-172
One new taxoid, 7-deacetyldecinnamoyltaxuspine B (1), and five known taxoids were isolated using silica gel chromatography from the crude methanolic extract of Taxus X media “Dark Green Spreader”. Their structures, were determined based on extens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd92381c64cc1c66a45492ac8f2506e4
https://doi.org/10.1080/10575639708041190
https://doi.org/10.1080/10575639708041190
Publikováno v:
Tetrahedron Letters. 38:2759-2762
The synthesis of regioisomeric bicyclo[9.3.1]pentadecane-3-one derivatives 1 and 2, interesting synthons for the preparation of novel diterpenoids, has been accomplished through an approach that entails as a key step the formation of a twelve-membere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5aaee34963572bf5f9aba740986bffac
https://doi.org/10.1016/s0040-4039(97)00463-2
https://doi.org/10.1016/s0040-4039(97)00463-2