Výsledky vyhledávání - "Taverne-Thiele A"

Akademický článek

Transcriptomic analysis of intestinal organoids, derived from pigs divergent in feed efficiency, and their response to Escherichia coli

Autor: Ole Madsen, Roxann S.C. Rikkers, Jerry M. Wells, Rob Bergsma, Soumya K. Kar, Nico Taverne, Anja J. Taverne-Thiele, Esther D. Ellen, Henri Woelders

Publikováno v: BMC Genomics, Vol 25, Iss 1, Pp 1-17 (2024)

Abstract Background There is increasing interest in using intestinal organoids to study complex traits like feed efficiency (FE) and host-microbe interactions. The aim of this study was to investigate differences in the molecular phenotype of organoi

Externí odkaz: https://doaj.org/article/b973fd59652944b992bee4c6300870fa

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Akademický článek

A collection of bacterial isolates from the pig intestine reveals functional and taxonomic diversity

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-26 (2020)

The authors present a public collection of 117 bacterial isolates from the pig gut, including the description of 38 novel taxa. Interesting functions discovered in these organisms include a new fucosyltransferease and sactipeptide-like molecules enco

Externí odkaz: https://doaj.org/article/861f155967b34cfe880cb9be03c3abdc

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Akademický článek

Effects of undigested protein-rich ingredients on polarised small intestinal organoid monolayers

Autor: Soumya K. Kar, Bart van der Hee, Linda M. P. Loonen, Nico Taverne, Johanna J. Taverne-Thiele, Dirkjan Schokker, Mari A. Smits, Alfons J. M. Jansman, Jerry M. Wells

Publikováno v: Journal of Animal Science and Biotechnology, Vol 11, Iss 1, Pp 1-7 (2020)

Abstract Here, we describe the use of monolayers of intestinal epithelial cells derived from intestinal organoids and transcriptomics to investigate the direct effects of dietary protein sources on epithelial function. Mechanically dissociated 3D org

Externí odkaz: https://doaj.org/article/2617e249b08a4e8893ce420bd80d57fc

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Akademický článek

Optimized procedures for generating an enhanced, near physiological 2D culture system from porcine intestinal organoids

Autor: B. van der Hee, L.M.P. Loonen, N. Taverne, J.J. Taverne-Thiele, H. Smidt, J.M. Wells

Publikováno v: Stem Cell Research, Vol 28, Iss , Pp 165-171 (2018)

An important practical limitation of the three-dimensional geometry of stem-cell derived intestinal organoids is that it prevents easy access to the apical epithelium for testing food components, microorganisms, bioactive and toxic compounds. To this

Externí odkaz: https://doaj.org/article/f2094fbf5f1b42b99324c82c8989c818

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Akademický článek

Dietary protein sources differentially affect microbiota, mTOR activity and transcription of mTOR signaling pathways in the small intestine.

Autor: Soumya K Kar, Alfons J M Jansman, Nirupama Benis, Javier Ramiro-Garcia, Dirkjan Schokker, Leo Kruijt, Ellen H Stolte, Johanna J Taverne-Thiele, Mari A Smits, Jerry M Wells

Publikováno v: PLoS ONE, Vol 12, Iss 11, p e0188282 (2017)

Dietary protein sources can have profound effects on host-microbe interactions in the gut that are critically important for immune resilience. However more knowledge is needed to assess the impact of different protein sources on gut and animal health

Externí odkaz: https://doaj.org/article/46cd49f934ce45a388223980488aa1dc

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