Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Tauromustine"'
Publikováno v:
In Vitro Cellular & Developmental Biology. Animal, 2009 Jan 01. 45(1/2), 32-34.
Externí odkaz:
https://www.jstor.org/stable/40205933
Publikováno v:
Current Medicinal Chemistry. 12:2021-2039
Taurine was discovered more than two hundred years ago from animal sources. It is distributed in both mammals and non-mammals and its content is high in several tissues. For more than a century-and-a-half, taurine was regarded just as an end product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37e55865a8ee006f0d0c64529fa3abf0
https://doi.org/10.2174/0929867054546582
https://doi.org/10.2174/0929867054546582
Publikováno v:
Xenobiotica. 29:783-792
1. The cytochrome P450 (CYP)-mediated metabolism of tauromustine has been evaluated in liver and lung microsomes from various species. Liver microsomes from rat pretreated with typical CYP inducers, human liver microsomes and cDNA-expressed human CYP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9c09a11eb7bd2c542b20fd8c0cc119b
https://doi.org/10.1080/004982599238236
https://doi.org/10.1080/004982599238236
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 45:32-34
The stability of two nitrosoureas, tauromustine and lomustine, has been investigated in different media and buffers. All media tested, except Leibovitz's L-15 medium, significantly increased the degradation rate of the investigated nitrosoureas at pH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e78f991d4f7a518aab95a72beebfcc71
https://doi.org/10.1007/s11626-008-9147-4
https://doi.org/10.1007/s11626-008-9147-4
Publikováno v:
Journal of Liquid Chromatography. 17:1597-1604
A reversed phase high performance liquid chromatography (HPLC) method was developed for the determination of tauromustine (TM) in presence of its metabolited in biological fluids and its degradation products in tablets. The proposed HPLC method was c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b2ef5ec7e4ff98a129f54ea91031211
https://doi.org/10.1080/10826079408013182
https://doi.org/10.1080/10826079408013182
Autor:
Mike C. Bibby, Simon R. Hill
Publikováno v:
Cancer Chemotherapy and Pharmacology. 34:57-62
The pharmacokinetic profiles of 5-fluorouracil (5-FU) and tauromustine (TCNU) were investigated in NMRI mice following their administration either alone or as part of simultaneous or sequential combinations. The profile of 5-FU remained unaltered irr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0a1d4cf9a1294a6943635f8aae5c950
https://doi.org/10.1007/bf00686112
https://doi.org/10.1007/bf00686112
Publikováno v:
International journal of oncology. 4(2)
The effect of administering divided dose schedules of TCNU was examined against the murine adenocarcinomas of the colon, MAC 13 and MAC 26, and the Lewis lung tumour and drug metabolism was examined in the different tumour bearing mouse strains. Bone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca9e37c15b0b3cd0c9798b4868ae4e45
https://pubmed.ncbi.nlm.nih.gov/21566938
https://pubmed.ncbi.nlm.nih.gov/21566938
Autor:
Fathalla Belal
Publikováno v:
Electroanalysis. 5:605-609
Tauromustine was found to be reducible at the dropping mercury electrode (DME) over the whole pH range in Britton-Robinson (BR) buffers. A well-defined cathodic wave was produced in the acid range, followed by an ill-defined, more negative additional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0659bb79607c0153a341400219c539f3
https://doi.org/10.1002/elan.1140050713
https://doi.org/10.1002/elan.1140050713
Publikováno v:
Carcinogenesis. 14:1143-1147
The denitrosation of a novel nitrosourea, 1-(2-chloroethyl)-3-[(2-dimethylaminosulfonyl)-ethyl]-1-nitrosoure a, tauromustine (TCNU), has been investigated in liver cytosol from various species and with a pool of cytosolic rat liver glutathione transf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a013883f1622149303474f049fdb8eb
https://doi.org/10.1093/carcin/14.6.1143
https://doi.org/10.1093/carcin/14.6.1143
Publikováno v:
British Journal of Cancer
Several investigators including ourselves have shown that hydralazine can potentiate the anti-tumour activity of certain agents against murine tumours probably by manipulating tumour blood flow. In order to investigate the effects of administration o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e10b07529baaa3773849b40030f58aa
https://doi.org/10.1038/bjc.1992.70
https://doi.org/10.1038/bjc.1992.70