E2F1 regulates cellular growth by mTOR signaling

Autor: Real, Sebastian, Meo-Evoli, Nathalie, Espada, Lilia, Tauler Girona, Albert

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname

During cell proliferation, growth must occur to maintain homeostatic cell size. Here we show that E2F1 is capable of inducing growth by regulating mTORC1 activity. The activation of cell growth and mTORC1 by E2F1 is dependent on both E2F1's ability t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8faf0a26eee4108dc689d56e74176339
http://hdl.handle.net/2445/21494

Regulation of hepatic 6-phosphofructo-2-kinase/fructose 2,6-biphosphatase gene expression by glucagon

Autor: Rosa López, José Luis, Ventura Pujol, Francesc, Tauler Girona, Albert, Bartrons Bach, Ramon

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona

The control of hepatic 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase gene expression by glucagon was studied. Intraperitoneal administration of glucagon rapidly decreased the fructose 2,6-bisphosphate content by phosphorylation of 6-phosphofru

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0850655d33d2285655a051abe686d085
http://hdl.handle.net/2445/177551

The Microtubule Nucleator γTuRC: Reconstitution and Analysis of its Assembly Mechanism

Autor: Zimmermann, Fabian

Publikováno v: TDX (Tesis Doctorals en Xarxa)
TDR. Tesis Doctorales en Red
instname
Dipòsit Digital de la UB
Universidad de Barcelona

[eng] The microtubule nucleator γ-tubulin ring complex (γTuRC) is essential for the function of microtubule organizing centers such as the centrosome. Since its discovery over two decades ago, γTuRC has evaded in vitro reconstitution and thus deta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3cc247127a90dbdcfd316c7431bee5c4
http://hdl.handle.net/10803/674183

The Tousled-like kinases and their implications in cancer and neurodevelopmental disorders

Autor: Villamor Payà, Marina

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
TDX (Tesis Doctorals en Xarxa)
TDR. Tesis Doctorales en Red
instname

[eng] The Tousled like kinases 1 and 2 (TLK1 and TLK2) are evolutionarily conserved Ser/Thr kinases that are required for genome stability and normal development in numerous organisms. Both kinases contribute to histone deposition by targeting the hi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2dbff793b86370343224748164c0f2ce
http://hdl.handle.net/2445/185527

CPEB4-Driven adipocyte reprogramming is required for adipogenesis and pathological inflammation

Autor: Pell Vidal, Núria

Publikováno v: TDX (Tesis Doctorals en Xarxa)
TDR. Tesis Doctorales en Red
Consejo Superior de Investigaciones Científicas (CSIC)
Dipòsit Digital de la UB
Universidad de Barcelona
TDR: Tesis Doctorales en Red
CBUC, CESCA

[eng] Obesity is reaching pandemic dimensions and is an established instigator of many diseases, such as non alcoholic fatty liver disease, the most prevalent liver disease worldwide. Most studies in this regard have been focused on obesity-related d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::01cb6c8ce33767ab6b808f5d88e8e026
http://hdl.handle.net/10803/671750