Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Taufik A Valiante"'
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 4, p e1010986 (2023)
Reduced cortical inhibition by somatostatin-expressing (SST) interneurons has been strongly associated with treatment-resistant depression. However, due to technical limitations it is impossible to establish experimentally in humans whether the effec
Externí odkaz:
https://doaj.org/article/75174db404d94480afb73b057926d14e
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0224547 (2019)
Sorting spikes from extracellular recording into clusters associated with distinct single units (putative neurons) is a fundamental step in analyzing neuronal populations. Such spike sorting is intrinsically unsupervised, as the number of neurons are
Externí odkaz:
https://doaj.org/article/32d25333e94a49ad94d315b35a6f8ca5
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68609 (2013)
Despite a wealth of EEG epilepsy data that accumulated for over half a century, our ability to understand brain dynamics associated with epilepsy remains limited. Using EEG data from 15 controls and 9 left temporal lobe epilepsy (LTLE) patients, in t
Externí odkaz:
https://doaj.org/article/c44e8fdd8cb746dc8307b0738be666b4
Autor:
Marjan Rafiee, Kramay Patel, David M. Groppe, Danielle M. Andrade, Eduard Bercovici, Esther Bui, Peter L. Carlen, Aylin Reid, Peter Tai, Donald Weaver, Richard Wennberg, Taufik A. Valiante
Publikováno v:
Epilepsia Open, Vol 5, Iss 2, Pp 285-294 (2020)
Abstract Objective Epilepsy is one of the most common neurological disorders . Many individuals continue to have seizures despite medical and surgical treatments, suggesting adjunctive management strategies are required. Promising effects of daily li
Externí odkaz:
https://doaj.org/article/3f397f46946d4587a733480a4864aed6
Autor:
Qinghua Wu, Peikai Zhang, Gerard O'Leary, Yimu Zhao, Yinghao Xu, Naimeh Rafatian, Sargol Okhovatian, Shira Landau, Taufik A Valiante, Jadranka Travas-Sejdic, Milica Radisic
Publikováno v:
Biofabrication.
We developed a heart-on-a-chip platform that integrates highly flexible, vertical, 3D micropillar electrodes for electrophysiological recording and elastic microwires for the tissue’s contractile force assessment. The high aspect ratio microelectro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae3b36854973e86504698fb20b9872cf
https://doi.org/10.1088/1758-5090/acd8f4
https://doi.org/10.1088/1758-5090/acd8f4
Autor:
Jie Zheng, Andrea G. P. Schjetnan, Mar Yebra, Bernard A. Gomes, Clayton P. Mosher, Suneil K. Kalia, Taufik A. Valiante, Adam N. Mamelak, Gabriel Kreiman, Ueli Rutishauser
Publikováno v:
Nature Neuroscience. 25:358-368
While experience is continuous, memories are organized as discrete events. Cognitive boundaries are thought to segment experience and structure memory, but how this process is implemented remains unclear. We recorded the activity of single neurons in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efe5148a2550d795c90a415b860ab96c
https://doi.org/10.1038/s41593-022-01020-w
https://doi.org/10.1038/s41593-022-01020-w
Autor:
Jonathan Daume, Jan Kaminski, Andrea G. P. Schjetnan, Yousef Salimpour, Umais Khan, Chrystal Reed, William Anderson, Taufik A. Valiante, Adam N. Mamelak, Ueli Rutishauser
Retaining information in working memory (WM) is a demanding process that relies on cognitive control to protect memoranda-specific persistent activity from interference. How cognitive control regulates WM storage, however, remains unknown. We hypothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cef2ae66b7ae7b9b01e9df848f35ca48
https://doi.org/10.1101/2023.04.05.535772
https://doi.org/10.1101/2023.04.05.535772
Autor:
Alexandre Guet-McCreight, Homeira Moradi Chameh, Frank Mazza, Thomas D. Prevot, Taufik A. Valiante, Etienne Sibille, Etay Hay
Reduced inhibition by somatostatin-expressing interneurons is associated with depression. Administration of positive allosteric modulators of α5 subunit-containing GABAAreceptor (α5-PAM) that selectively target this lost inhibition exhibit antidepr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b504a5bd08c60702c10cad67ba1e236
https://doi.org/10.1101/2023.02.22.529541
https://doi.org/10.1101/2023.02.22.529541
Discerning the contribution of specific ionic currents to complex neuronal dynamics is a difficult, but important, task. This challenge is exacerbated in the human setting, although the widely-characterized uniqueness of the human brain as compared t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29762212f1228b27b3556e13b5b488c3
https://doi.org/10.1101/2023.02.13.528352
https://doi.org/10.1101/2023.02.13.528352
Seizures are classically described as an epiphenomenon of hyperexcitability and hypersynchronicity across brain regions. However, this view is insufficient to explain the complex, dynamic evolution of focal-onset seizures in the brain. Recent studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0af3fbf48c91fb3413bbc1916f89111e
https://doi.org/10.1101/2023.01.16.524224
https://doi.org/10.1101/2023.01.16.524224