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T cell regulation in microgravity – The current knowledge from in vitro experiments conducted in space, parabolic flights and ground-based facilities

Autor: Hauschild, Swantje, Tauber, Svantje, Lauber, Beatrice, Thiel, Cora S., Layer, Liliana E., Ullrich, Oliver

Publikováno v: In Acta Astronautica November 2014 104(1):365-377

Rapid Downregulation of H3K4me3 Binding to Immunoregulatory Genes in Altered Gravity in Primary Human M1 Macrophages

Autor: Vahlensieck, Christian, Thiel, Cora Sandra, Christoffel, Swantje, Herbst, Sabrina, Polzer, Jennifer, Lauber, Beatrice Astrid, Wolter, Saskia, Layer, Liliana Elisabeth, Hinkelbein, Jochen, Tauber, Svantje, Ullrich, Oliver

Publikováno v: International Journal of Molecular Sciences; Volume 24; Issue 1; Pages: 603

The sensitivity of human immune system cells to gravity changes has been investigated in numerous studies. Human macrophages mediate innate and thus rapid immune defense on the one hand and activate T- and B-cell-based adaptive immune response on the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5f08ff64ea9d50fe99d26d479dec7d5
https://doi.org/10.3390/ijms24010603

Rapid coupling between gravitational forces and the transcriptome in human myelomonocytic U937 cells.

Autor: Thiel, Cora S.^1,2 (AUTHOR) cora.thiel@uzh.ch, Tauber, Svantje^1,2 (AUTHOR), Christoffel, Swantje^1,2 (AUTHOR), Huge, Andreas³ (AUTHOR), Lauber, Beatrice A.¹ (AUTHOR), Polzer, Jennifer¹ (AUTHOR), Paulsen, Katrin¹ (AUTHOR), Lier, Hartwin⁴ (AUTHOR), Engelmann, Frank^4,5 (AUTHOR), Schmitz, Burkhard⁶ (AUTHOR), Schütte, Andreas⁶ (AUTHOR), Raig, Christiane¹ (AUTHOR), Layer, Liliana E.¹ (AUTHOR), Ullrich, Oliver^1,2,7 (AUTHOR) oliver.ullrich@uzh.ch

Publikováno v: Scientific Reports. 9/5/2018, Vol. 8 Issue 1, p1-11. 11p.

Rapid Cellular Perception of Gravitational Forces in Human Jurkat T Cells and Transduction into Gene Expression Regulation

Autor: Thiel, Cora Sandra, Christoffel, Swantje, Tauber, Svantje, Vahlensieck, Christian, de Zélicourt, Diane, Layer, Liliana E, Lauber, Beatrice, Polzer, Jennifer, Ullrich, Oliver

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 2, p 514 (2020)
International Journal of Molecular Sciences

Cellular processes are influenced in many ways by changes in gravitational force. In previous studies, we were able to demonstrate, in various cellular systems and research platforms that reactions and adaptation processes occur very rapidly after th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ef25066c91efb3605ffb90866f48041c
https://www.mdpi.com/1422-0067/21/2/514