Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Taube P. Rothman"'
Publikováno v:
Journal of Neuroscience Research. 59:384-401
Kit is a marker for interstitial cells of Cajal (ICC). ICCs interact with enteric neurons and are essential for gastrointestinal motility. The roles of neural crest-derived cells, neurons, Kit, and Kit ligand (KL) in ICC development were analyzed. IC
Publikováno v:
Development. 126:1161-1173
The terminal colon is aganglionic in mice lacking endothelin-3 or its receptor, endothelin B. To analyze the effects of endothelin-3/endothelin B on the differentiation of enteric neurons, E11-13 mouse gut was dissociated, and positive and negative i
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 275:G433-G448
Studies of the guinea pig small intestine have suggested that serotonin (5-HT) may be a mucosal transmitter that stimulates sensory nerves and initiates peristaltic and secretory reflexes. We tested the hypothesis that guinea pig villus epithelial ce
Autor:
Taube P. Rothman, Jingxian Chen, A. John MacLennan, Michael D. Gershon, Alcmène Chalazonitis, Emily N. Vinson
Publikováno v:
Developmental Biology. 198(2):343-365
Neurotrophin-3 (NT-3) is known to promote enteric neuronal and glial development. Ciliary neurotrophic factor (CNTF) and leukemia inhibitory factor (LIF) were investigated to test the hypothesis that the development of subsets of enteric neurons and/
Autor:
Maura C. Kibbey, Michael D. Gershon, Alcmène Chalazonitis, Virginia M. Tennyson, Taube P. Rothman
Publikováno v:
Journal of Neurobiology. 33:118-138
A plasmalemmal protein, LBP110, which binds to the α1 chain of laminin-1, is acquired by the neural crest-derived precursors of enteric neurons after they colonize the gut. We tested the hypothesis that laminin-1 interacts with LBP110 to promote ent
Autor:
Anita Schuchardt, Taube P. Rothman, Marthe J. Howard, Jingxian Chen, Vassilis Pachnis, Frank Costantini, Michael D. Gershon
Publikováno v:
Developmental Biology. 178(2):498-513
Extracellular matrix molecules, including laminin, affect the development of enteric neurons and accumulate in the aganglionic colon of ls/ls mice. Quantitative Northern analysis revealed that mRNAs encoding the beta 1 and gamma 1 subunits of laminin
Publikováno v:
Developmental Biology. 159:559-573
The terminal bowel is congenitally aganglionic in ls/ls mice. The condition has been associated with an overabundance of laminin and other matrix molecules. Aggregation ls/ls==C3H chimeric mice and interspecies mouse==quail chimeras were constructed
Publikováno v:
Developmental Dynamics. 196:217-233
The enteric nervous system (ENS) in avian embryos is formed by cells that migrate to the bowel from vagal and sacral regions of the neural crest. Experiments were carried out to evaluate the developmental potential of crest-derived cells at the time
Publikováno v:
Journal of Neurobiology. 24:199-214
The ENS resembles the brain and differs both physiologically and structurally from any other region of the PNS. Recent experiments in which crest cell migration has been studied with DiI, a replication-deficient retrovirus, or antibodies that label c
Publikováno v:
Development. 111:647-655
Experiments were done to test the hypothesis that the avian gut is colonized by cells derived from both vagal and sacral regions of the neural crest. A fluorescent dye, dil (l,l-dioctadecyl-3,3,3′,3′-tetramethylmdocarbocya-nine perchlorate), and