Zobrazeno 1 - 10
of 235
pro vyhledávání: '"Tau Imaging"'
Autor:
Naresh Damuka, Miranda E. Orr, Avinash H. Bansode, Ivan Krizan, Mack Miller, Jillian Lee, Shannon L. Macauley, Christopher T. Whitlow, Akiva Mintz, Suzanne Craft, Kiran Kumar Solingapuram Sai
Publikováno v:
EJNMMI Research, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Background Microtubules (MTs) are critical for cell structure, function, and survival. MT instability may contribute to Alzheimer’s disease (AD) pathogenesis as evidenced by persistent negative regulation (phosphorylation) of the neuronal
Externí odkaz:
https://doaj.org/article/55965fc1ff5845699b0af3989855e83d
A dual-time-window protocol to reduce acquisition time of dynamic tau PET imaging using [18F]MK-6240
Autor:
Guilherme D. Kolinger, David Vállez García, Talakad G. Lohith, Eric D. Hostetler, Cyrille Sur, Arie Struyk, Ronald Boellaard, Michel Koole
Publikováno v:
EJNMMI Research, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Background [18F]MK-6240 is a PET tracer with sub-nanomolar affinity for neurofibrillary tangles. Therefore, tau quantification is possible with [18F]MK-6240 PET/CT scans, and it can be used for assessment of Alzheimer’s disease. However, l
Externí odkaz:
https://doaj.org/article/6e7fdb746120410b8c67c2492e6930e4
Autor:
Matthias Brendel, Cihan Catak, Leonie Beyer, Jennifer Linn, Hannes Wahl, Daniel Janowitz, Axel Rominger, Marianne Patt, Henryk Barthel, Osama Sabri, Peter Bartenstein, Frank Arne Wollenweber
Publikováno v:
Case Reports in Neurology, Vol 12, Iss 2, Pp 232-237 (2020)
Cortical superficial siderosis (cSS) is a common feature in patients with cerebral amyloid angiopathy (CAA). The correlation between β-amyloid and/or tau pathology and the occurrence of cSS is unclear. We report on an 80-year-old male patient who wa
Externí odkaz:
https://doaj.org/article/b177c06ffea841f084abc5ba49da8a8a
Autor:
YU Qian;LI Yuying;PENG Cheng
Publikováno v:
Journal of Isotopes (2021)
Neurofibrillary tangles (NFTs) are regard as a crucial pathological hallmark of various neurodegenerative disorders, including Alzheimer’s disease (AD) and some frontotemporal dementias. Recently, a diversity of chemical molecules has been reported
Externí odkaz:
https://doaj.org/article/c5af6af5adc24dbf9257643603578b76
Autor:
Yuan Li, Zhijun Yao, Yue Yu, Ying Zou, Yu Fu, Bin Hu, for the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
BMC Psychiatry, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background Amyloid β (Aβ) and tau proteins are considered as critical factors that affect Alzheimer’s disease (AD) and mild cognitive impairment (MCI). Although many studies have conducted on these two proteins, little study has investig
Externí odkaz:
https://doaj.org/article/7e62e468fce446b4a57cbfe7d0ad77db
Autor:
Richard M. Tsai, Alexandre Bejanin, Orit Lesman-Segev, Renaud LaJoie, Adrienne Visani, Viktoriya Bourakova, James P. O’Neil, Mustafa Janabi, Suzanne Baker, Suzee E. Lee, David C. Perry, Lynn Bajorek, Anna Karydas, Salvatore Spina, Lea T. Grinberg, William W. Seeley, Eliana M. Ramos, Giovanni Coppola, Maria Luisa Gorno-Tempini, Bruce L. Miller, Howard J. Rosen, William Jagust, Adam L. Boxer, Gil D. Rabinovici
Publikováno v:
Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-18 (2019)
Abstract Background The tau positron emission tomography (PET) ligand 18F-flortaucipir binds to paired helical filaments of tau in aging and Alzheimer’s disease (AD), but its utility in detecting tau aggregates in frontotemporal dementia (FTD) is u
Externí odkaz:
https://doaj.org/article/1733aae59d224cd5a72a1f4f4fc79342
Akademický článek
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Autor:
Andrew V. Mossine, Allen F. Brooks, Bradford D. Henderson, Brian G. Hockley, Kirk A. Frey, Peter J. H. Scott
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 2, Iss 1, Pp 1-13 (2017)
Abstract Background [18F]AV1451 is a commonly used radiotracer for imaging tau deposits in Alzheimer’s disease (AD) and related non-AD tauopathies. Existing radiosyntheses of [18F]AV1451 require complex purifications to provide doses suitable for u
Externí odkaz:
https://doaj.org/article/ef110d37a10e402ba86f97cc0a604a66
Publikováno v:
Chinese Medical Journal, Vol 130, Iss 24, Pp 2978-2990 (2017)
Objective: To review recent research advances on tau, a major player in Alzheimer's disease (AD) pathogenesis, a biomarker for AD onset, and potential target for AD therapy. Data Sources: This review was based on a comprehensive search using online l
Externí odkaz:
https://doaj.org/article/309a97328427420cb646bc2c8ff4fdd0
Akademický článek
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