Výsledky vyhledávání - "Tatyana Zyubko"

Akademický článek

Reiterative Synthesis by the Ribosome and Recognition of the N-Terminal Formyl Group by Biosynthetic Machinery Contribute to Evolutionary Conservation of the Length of Antibiotic Microcin C Peptide Precursor

Autor: Inna Zukher, Michael Pavlov, Darya Tsibulskaya, Alexey Kulikovsky, Tatyana Zyubko, Dmitry Bikmetov, Marina Serebryakova, Satish K. Nair, Måns Ehrenberg, Svetlana Dubiley, Konstantin Severinov

Publikováno v: mBio, Vol 10, Iss 2 (2019)

ABSTRACT Microcin C (McC) is a peptide adenylate antibiotic produced by Escherichiacoli cells bearing a plasmid-borne mcc gene cluster. Most MccA precursors, encoded by validated mcc operons from diverse bacteria, are 7 amino acids long, but the sign

Externí odkaz: https://doaj.org/article/1320d8f1afa64361aa8de0fbe621008b

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PpCas9 from Pasteurella pneumotropica — a compact Type II-C Cas9 ortholog active in human cells

Autor: Maksim Kazalov, Mikhail Khodorkovskii, Anatolii Arseniev, Polina Selkova, Sergey Shmakov, T. O. Artamonova, Aleksandra Vasileva, Daria Artamonova, Olga Musharova, Ignatiy Goryanin, Tatyana Zyubko, Konstantin Severinov, Iana Fedorova, Georgii Pobegalov, Marina Abramova

Publikováno v: Nucleic Acids Research

CRISPR-Cas defense systems opened up the field of genome editing due to the ease with which effector Cas nucleases can be programmed with guide RNAs to access desirable genomic sites. Type II-A SpCas9 from Streptococcus pyogenes was the first Cas9 nu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18c51d476fa75cbb9b79cbfc30b7453f
https://doi.org/10.1093/nar/gkaa998

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Position of Deltaproteobacteria Cas12e nuclease cleavage sites depends on spacer length of guide RNA

Autor: Maksim Kazalov, Konstantin Severinov, Nataliia Shcheglova, Aleksandra Vasileva, Polina Selkova, T. O. Artamonova, Iana Fedorova, Tatyana Zyubko, Anatolii Arseniev, Georgii Pobegalov, Olga Musharova, Mikhail Khodorkovskii

Publikováno v: RNA Biology
article-version (VoR) Version of Record

Cas12e proteins (formerly CasX) form a distinct subtype of Class II type V CRISPR-Cas effectors. Recently, it was shown that DpbCas12e from Deltaproteobacteria and PlmCas12e from Planctomycetes can introduce programmable double-stranded breaks in mam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e91779ee9c44ab505ddd1ff75715ba13
http://europepmc.org/articles/PMC7549622

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DNA targeting by Clostridium cellulolyticum CRISPR–Cas9 Type II-C system

Autor: Marina Abramova, Daria Artamonova, Ignatiy Goryanin, Olga Musharova, Mikhail Khodorkovskii, Konstantin Severinov, Sergey Shmakov, Georgii Pobegalov, Polina Selkova, T. O. Artamonova, Tatyana Zyubko, Maksim Kazalov, Aleksandra Vasileva, Anatolii Arseniev, Iana Fedorova

Publikováno v: Nucleic Acids Research

Type II CRISPR–Cas9 RNA-guided nucleases are widely used for genome engineering. Type II-A SpCas9 protein from Streptococcus pyogenes is the most investigated and highly used enzyme of its class. Nevertheless, it has some drawbacks, including a rel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9adf1dfe831092ce6078be606074b64
https://doi.org/10.1093/nar/gkz1225

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Efficient in vivo synthesis of lasso peptide pseudomycoidin proceeds in the absence of both the leader and the leader peptidase

Autor: Marina V. Serebryakova, Svetlana Dubiley, Julia Andreeva, Mikhail Metelev, Konstantin Severinov, Guy Lippens, Tatyana Zyubko

Publikováno v: Chemical Science. 10:9699-9707

Bacterial lasso peptides are made from linear ribosomally synthesized precursors by specific cleavage at the leader-core junction site of the precursor by a dedicated protease recognizing the leader, followed by cyclisation of the newly formed N-term

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a5c65be59ab01d4a6e6179f62285b32
https://doi.org/10.1039/c9sc02370d

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Reiterative synthesis by the ribosome and recognition of the N-terminal formyl group by biosynthetic machinery contribute to evolutionary conservation of the length of antibiotic microcin C peptide precursor

Autor: Alexey Kulikovsky, Darya Tsibulskaya, Måns Ehrenberg, Dmitry Bikmetov, Svetlana Dubiley, Inna Zukher, Konstantin Severinov, Michael Y. Pavlov, Tatyana Zyubko, Marina V. Serebryakova, Satish K. Nair

Publikováno v: mBio, Vol 10, Iss 2 (2019)
mBio, Vol 10, Iss 2, p e00768-19 (2019)

Microcin C (McC) is a peptide adenylate antibiotic produced by Escherichiacoli cells bearing a plasmid-borne mcc gene cluster. Most MccA precursors, encoded by validated mcc operons from diverse bacteria, are 7 amino acids long, but the significance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82f38bbc05c10206bd1d89cdd4bff778
http://ora.ox.ac.uk/objects/uuid:

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