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pro vyhledávání: '"Tatyana Yu Prokhorova"'
Autor:
Alexander A. Spasov, Tatyana Yu Prokhorova, Diana R. Muleeva, Denis A. Babkov, Yuri N. Klimochkin, Vitaly A. Osyanin, Dmitry V. Osipov, Ekaterina A. Sturova, Maxim R. Demidov
Publikováno v:
Chemical Biology & Drug Design. 90:1184-1189
A series of benzofuran derivatives was synthesized as analogues of known natural α-glucosidase inhibitors. Their activity was evaluated in enzymatic assay and in rat model of diabetes mellitus. Newly identified inhibitors demonstrate significant pot