Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Tatyana V, Nasedkina"'
Autor:
Tatyana S. Belysheva, Tatyana V. Nasedkina, Iryna S. Kletskaya, Anastasiya S. Volkova, Vera V. Semenova, Timur T. Valiev
Publikováno v:
Вопросы современной педиатрии, Vol 20, Iss 6s, Pp 611-617 (2021)
Xeroderma pigmentosum is rare genetic disorder characterized by increased skin sensitivity to damaging ultraviolet (UV) light. First symptoms manifest at early age in most cases (up to 75%). Chronic damage due to sun exposure is common, it has differ
Externí odkaz:
https://doaj.org/article/eca47751e5434916bd63aff1220d63c3
Autor:
Alexander S. Zasedatelev, V. E. Shershov, Sergey A. Lapa, T. O. Guseinov, V. E. Kuznetsova, Мarina А. Emelyanova, M. A. Spitsyn, Alexander V. Chudinov, Tatyana V. Nasedkina
Publikováno v:
Dyes and Pigments. 147:199-210
Two series of novel zwitterionic water-soluble pentamethine cyanine dyes with geometrically balanced structures were synthesized and characterized. One series of cyanine dyes is the «zwitterionic» fluorophores, which contain positively charged trim
Autor:
Alexander S. Zasedatelev, Sergey A. Lapa, Evgeniy E. Fesenko, V. E. Kuznetsova, Tatyana V. Nasedkina, V. E. Shershov, T. O. Guseinov, M. A. Spitsyn, Mariya A. Avdonina, Alexander V. Chudinov, Anna Yu. Ikonnikova
Publikováno v:
Mendeleev Communications. 26:95-98
The novel C5-modified nucleotides containing indodicarbocyanine dye bearing a carboxyl group at the 3-position of indolenine have been synthesized and incorporated into DNA by commercially available thermostable Taq DNA polymerase. The efficiency of
Autor:
Olga Kalennik, Irina Kalinina, Mikhail Maschan, Tatyana V. Nasedkina, Yuliya Yatsenko, Alexey Maschan
Publikováno v:
Journal of Pediatric Hematology/Oncology. 35:e100-e108
We evaluated frequencies of NPM1, FLT3, c-KIT mutations in childhood acute myeloid leukemia (AML) in Russia and assessed prognostic relevance of the mutations. RNA and DNA were extracted from bone marrow samples of 186 (106 male and 80 female) pediat
Autor:
Tatyana V. Nasedkina, Alexander S. Zasedatelev, L. N. Lyubchenko, Vladimir Shamanin, M. A. Emelyanova, Lev V. Demidov
Publikováno v:
Cancer biomarkers : section A of Disease markers. 16(1)
Background The activating mutation BRAF V600E is considered to be a diagnostic cutaneous melanoma (CM) marker important for prognosis and targeted therapy. Objective The aim of this study was to determine the frequency of the V600E mutation in CM pat
Autor:
Eugene Y. Krynetski, Elena Samochatova, William E. Evans, Natalia V. Chupova, Anastassia Rudneva, Olga A. Maiorova, Tatyana V. Nasedkina, Raul C. Ribeiro, Olga Makarova, O. E. Fedorova, Natalia F. Krynetskaia, Alexander G. Roumyantsev, Andrei S. Glotov, Zh. M. Kozhekbaeva
Publikováno v:
Pediatric Blood & Cancer. 52:203-208
Background Polymorphisms that reduce the activity of thiopurine S-methyltransferase (TPMT) cause adverse reactions to conventional doses of thiopurines, routinely used for antileukemic and immunosuppressive treatment. There are more than 20 variant a
Publikováno v:
Molecular Biology. 42:187-197
Polymorphisms of xenobiotic-metabolizing genes correlate with hereditary predisposition to neoplasia in some cases. The frequencies of polymorphisms of xenobiotic-metabolizing genes were determined in 332 children with acute lymphoblastic leukemia, 7
Autor:
V. E. Kuznetsova, Eugene Nikitin, Tatyana V. Nasedkina, Alexander V. Chudinov, Oleg S. Glotov, Andrey Sudarikov, O. A. Gra, Andrey S. Glotov
Publikováno v:
American Journal of Hematology. 83:279-287
Polymorphisms in genes coding xenobiotic-metabolizing enzymes are considered as risk factors modifying susceptibility to cancer. We developed a biochip for the analysis of 18 mutations in 10 genes of metabolizing system: CYP1A1, CYP2D6, GSTT1, GSTM1,
Autor:
Eugene Nikitin, Sergey Surzhikov, Julia V. Sidorova, Tatyana V. Nasedkina, Anait L. Melikyan, Alexander S. Zasedatelev, A. Y. Turygin, Andrey Sudarikov, O. A. Gra
Publikováno v:
The Journal of Molecular Diagnostics. 9:249-257
T-cell clonality estimation is important for the differential diagnosis between malignant and nonmalignant T-cell proliferation. Routinely used methods include polymerase chain reaction (PCR) analysis of T-cell receptor-γ (TCR-γ) gene rearrangement
Autor:
R. F. Garkavtseva, Tatiana P. Kazubskaya, O. E. Fedorova, Tatyana V. Nasedkina, Alexander S. Zasedatelev, F. A. Amosenko, L. N. Lyubchenko, Yu. G Payanidi
Publikováno v:
Molecular Biology. 41:32-36
Ovarian cancer (OC) is among the leading causes of cancer-related mortality in women. A high risk of OC (lifetime estimates ranging 10–60%) is determined by BRCA1/2 mutations. The 1100delC variant of CHEK2 is associated with predisposition to breas