Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Tatyana Pyntikova"'
Autor:
Adrianna K. San Roman, Helen Skaletsky, Alexander K. Godfrey, Neha V. Bokil, Levi Teitz, Isani Singh, Laura V. Blanton, Daniel W. Bellott, Tatyana Pyntikova, Julian Lange, Natalia Koutseva, Jennifer F. Hughes, Laura Brown, Sidaly Phou, Ashley Buscetta, Paul Kruszka, Nicole Banks, Amalia Dutra, Evgenia Pak, Patricia C. Lasutschinkow, Colleen Keen, Shanlee M. Davis, Angela E. Lin, Nicole R. Tartaglia, Carole Samango-Sprouse, Maximilian Muenke, David C. Page
Publikováno v:
Cell Genomics, Vol 4, Iss 1, Pp 100462- (2024)
Summary: Somatic cells of human males and females have 45 chromosomes in common, including the “active” X chromosome. In males the 46th chromosome is a Y; in females it is an “inactive” X (Xi). Through linear modeling of autosomal gene expres
Externí odkaz:
https://doaj.org/article/f7bcee4c14104a018d0e1ee125035ddd
Autor:
Jennifer F. Hughes, Helen Skaletsky, Peter K. Nicholls, Alexis Drake, Tatyana Pyntikova, Ting-Jan Cho, Daniel W. Bellott, David C. Page
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-13 (2022)
Abstract Background The mammalian X and Y chromosomes originated from a pair of ordinary autosomes. Over the past ~180 million years, the X and Y have become highly differentiated and now only recombine with each other within a short pseudoautosomal
Externí odkaz:
https://doaj.org/article/36f0d6bd4f974647b276c82792290331
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 5, Pp 1481-1486 (2019)
The introduction of foreign DNA into cells and organisms has facilitated much of modern biological research, and it promises to become equally important in clinical practice. Locating sites of foreign DNA incorporation in mammalian genomes has proven
Externí odkaz:
https://doaj.org/article/2f2e57f8ab17474796dc5a12d42d188d
Autor:
Ting-Jan Cho, Jennifer F. Hughes, Donna M. Muzny, James E. Womack, Kim C. Worley, Laura G. Brown, Lucinda Fulton, Catrina Fronick, Daniel W. Bellott, Bhanu P. Chowdhary, Elaine Owens, David C. Page, Shannon Dugan-Rocha, Tina A. Graves-Lindsay, Natalia Koutseva, Terje Raudsepp, Colin Kremitzki, Tatyana Pyntikova, Ziad Khan, William J. Murphy, Helen Skaletsky, Richard A. Gibbs, Wesley C. Warren, Richard K. Wilson
Publikováno v:
Genome Research. 30:1716-1726
Studies of Y Chromosome evolution have focused primarily on gene decay, a consequence of suppression of crossing-over with the X Chromosome. Here, we provide evidence that suppression of X–Y crossing-over unleashed a second dynamic: selfish X–Y a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b6b7baf035063fb9a1606b28c937627
https://doi.org/10.1101/gr.269902.120
https://doi.org/10.1101/gr.269902.120
Autor:
Weijie Lan, Dong Hyun Kim, Don W. Cleveland, Peter J. Campbell, Ofer Shoshani, Adrienne M. Flanagan, David C. Page, Sam Behjati, Simon F. Brunner, Peter Ly, Tatyana Pyntikova
Publikováno v:
Nature genetics
Cancer genomes are frequently characterized by numerical and structural chromosomal abnormalities. Here we integrated a centromere-specific inactivation approach with selection for a conditionally essential gene, a strategy termed CEN-SELECT, to syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca6b94297842bc6fb0d465790f74438
https://doi.org/10.1038/s41588-019-0360-8
https://doi.org/10.1038/s41588-019-0360-8
Publikováno v:
G3: Genes|Genomes|Genetics
G3: Genes, Genomes, Genetics, Vol 9, Iss 5, Pp 1481-1486 (2019)
G3: Genes, Genomes, Genetics, Vol 9, Iss 5, Pp 1481-1486 (2019)
The introduction of foreign DNA into cells and organisms has facilitated much of modern biological research, and it promises to become equally important in clinical practice. Locating sites of foreign DNA incorporation in mammalian genomes has proven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a83fb84a22b64620dcf486230ed012e2
http://europepmc.org/articles/PMC6505145
http://europepmc.org/articles/PMC6505145
Autor:
Jennifer F. Hughes, Tatyana Pyntikova, Helen Skaletsky, David C. Page, Ting-Jan Cho, Emily K. Jackson, Daniel W. Bellott
Publikováno v:
Genome Res
Mammalian sex chromosomes carry large palindromes that harbor protein-coding gene families with testis-biased expression. However, there are few known examples of sex-chromosome palindromes conserved between species. We identified 26 palindromes on t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2cf4a908401844384ce1a664861b396
https://doi.org/10.1101/2020.12.29.424738
https://doi.org/10.1101/2020.12.29.424738
Autor:
Jennifer F, Hughes, Helen, Skaletsky, Tatyana, Pyntikova, Natalia, Koutseva, Terje, Raudsepp, Laura G, Brown, Daniel W, Bellott, Ting-Jan, Cho, Shannon, Dugan-Rocha, Ziad, Khan, Colin, Kremitzki, Catrina, Fronick, Tina A, Graves-Lindsay, Lucinda, Fulton, Wesley C, Warren, Richard K, Wilson, Elaine, Owens, James E, Womack, William J, Murphy, Donna M, Muzny, Kim C, Worley, Bhanu P, Chowdhary, Richard A, Gibbs, David C, Page
Publikováno v:
Genome Res
Studies of Y Chromosome evolution have focused primarily on gene decay, a consequence of suppression of crossing-over with the X Chromosome. Here, we provide evidence that suppression of X–Y crossing-over unleashed a second dynamic: selfish X–Y a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6834ccf44df4357639c19d3ce4a54b3d
https://pubmed.ncbi.nlm.nih.gov/33208454
https://pubmed.ncbi.nlm.nih.gov/33208454
Autor:
Helen Skaletsky, Wesley C. Warren, Elena Gaginskaya, Richard K. Wilson, Devin P. Locke, Laura J. E. Brown, Colin Kremitzki, Svetlana Galkina, David C. Page, Daniel W. Bellott, Natalia Koutseva, Andrew G. Clark, Nancy F. Chen, Ting Jan Cho, Tatyana Pyntikova, Tina Graves
Publikováno v:
Nature genetics
After birds diverged from mammals, different ancestral autosomes evolved into sex chromosomes in each lineage. In birds, females are ZW and males are ZZ, but in mammals females are XX and males are XY. We sequenced the chicken W chromosome, compared
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d64e5285b42dd3952717fb6dcd92505
https://doi.org/10.1038/ng.3778
https://doi.org/10.1038/ng.3778
The introduction of foreign DNA into cells and organisms has facilitated much of modern biological research, and it promises to become equally important in clinical practice. Locating sites of foreign DNA incorporation in mammalian genomes has proven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2390395cf4e5cd270e56ba49f094bea0
https://doi.org/10.1101/520627
https://doi.org/10.1101/520627