Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Tatyana I. Gudz"'
Autor:
Sergei A. Novgorodov, Joshua R. Voltin, Wenxue Wang, Stephen Tomlinson, Christopher L. Riley, Tatyana I. Gudz
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 3, Pp 609-623 (2019)
Traumatic brain injury (TBI) is one of the leading causes of disability worldwide and a prominent risk factor for neurodegenerative diseases. The expansion of nervous tissue damage after the initial trauma involves a multifactorial cascade of events,
Externí odkaz:
https://doaj.org/article/871a7061fb534e43ab549db5626eb3e6
Acid sphingomyelinase promotes mitochondrial dysfunction due to glutamate-induced regulated necrosis
Autor:
Sergei A. Novgorodov, Joshua R. Voltin, Monika A. Gooz, Li Li, John J. Lemasters, Tatyana I. Gudz
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 2, Pp 312-329 (2018)
Inhibiting the glutamate/cystine antiporter system xc−, a key antioxidant defense machinery in the CNS, could trigger a novel form of regulated necrotic cell death, ferroptosis. The underlying mechanisms of system xc−-dependent cell demise were e
Externí odkaz:
https://doaj.org/article/5d17b8b1a7db4a9380cbce661a337c73
Autor:
Sergei A. Novgorodov, Christopher L. Riley, Jin Yu, Jarryd A. Keffler, Christopher J. Clarke, An O. Van Laer, Catalin F. Baicu, Michael R. Zile, Tatyana I. Gudz
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 4, Pp 546-562 (2016)
Sphingolipids have been implicated as key mediators of cell-stress responses and effectors of mitochondrial function. To investigate potential mechanisms underlying mitochondrial dysfunction, an important contributor to diabetic cardiomyopathy, we ex
Externí odkaz:
https://doaj.org/article/2d1d76ffc43548edb12f8315bbb1ea78
Autor:
Christopher L. Riley, Tatyana I. Gudz, Joshua Voltin, Sergei A. Novgorodov, Stephen Tomlinson, Wenxue Wang
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 3, Pp 609-623 (2019)
Traumatic brain injury (TBI) is one of the leading causes of disability worldwide and a prominent risk factor for neurodegenerative diseases. The expansion of nervous tissue damage after the initial trauma involves a multifactorial cascade of events,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ca5570d8dde1202ba766d0b18846419
http://www.sciencedirect.com/science/article/pii/S0022227520326225
http://www.sciencedirect.com/science/article/pii/S0022227520326225
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb4e2ba5450a962f73313704a1d942f3
https://doi.org/10.1096/fasebj.2019.33.1_supplement.660.10
https://doi.org/10.1096/fasebj.2019.33.1_supplement.660.10
Autor:
Sergei A. Novgorodov, David B. Lombard, Christopher L. Riley, Tatyana I. Gudz, Mark S. Kindy, Wendy B. Macklin, Jarryd A. Keffler, Jin Yu
Publikováno v:
Journal of Biological Chemistry. 291:1957-1973
Experimental evidence supports the role of mitochondrial ceramide accumulation as a cause of mitochondrial dysfunction and brain injury after stroke. Herein, we report that SIRT3 regulates mitochondrial ceramide biosynthesis via deacetylation of cera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b3b98207b2a62af2e4c5d2fa8754e4b
https://doi.org/10.1074/jbc.m115.668228
https://doi.org/10.1074/jbc.m115.668228
Autor:
Tatyana I. Gudz, Adam J Harrington, Joshua Voltin, Sergei A. Novgorodov, Christopher W. Cowan
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61c22f163166cf81ce20d2c5e43afd8a
https://doi.org/10.1096/fasebj.2020.34.s1.09315
https://doi.org/10.1096/fasebj.2020.34.s1.09315
Acid sphingomyelinase promotes mitochondrial dysfunction due to glutamate-induced regulated necrosis
Autor:
Monika A. Gooz, Joshua Voltin, John J. Lemasters, Li Li, Tatyana I. Gudz, Sergei A. Novgorodov
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 2, Pp 312-329 (2018)
Inhibiting the glutamate/cystine antiporter system xc−, a key antioxidant defense machinery in the CNS, could trigger a novel form of regulated necrotic cell death, ferroptosis. The underlying mechanisms of system xc−-dependent cell demise were e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1564b152b97840c4fa636ca363e1ba2
https://pubmed.ncbi.nlm.nih.gov/29282302
https://pubmed.ncbi.nlm.nih.gov/29282302
Autor:
Yusuf A. Hannun, Tatyana I. Gudz, Richard L. Proia, Christopher L. Riley, Keith T. Borg, Sergei A. Novgorodov, Mark S. Kindy, Jin Yu
Publikováno v:
Journal of Biological Chemistry. 289:13142-13154
In addition to immediate brain damage, traumatic brain injury (TBI) initiates a cascade of pathophysiological events producing secondary injury. The biochemical and cellular mechanisms that comprise secondary injury are not entirely understood. Herei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72945c4e450144bef987f382ad6cf64c
https://doi.org/10.1074/jbc.m113.530311
https://doi.org/10.1074/jbc.m113.530311
Autor:
Paul Breen, Jacqueline M. Kraveka, Nithin B. Boppana, Jason S. Pierce, Li Li, Mehrdad Rahmaniyan, Jacek Bielawski, Nicholas Joseph, Mladen Korbelik, Aiping Bai, Alicja Bielawska, Tatyana I. Gudz, Eric Van Buren, Duska Separovic
Publikováno v:
International Journal of Oncology
Photodynamic therapy (PDT) is not always effective as an anticancer treatment, therefore, PDT is combined with other anticancer agents for improved efficacy. The combination of dasatinib and PDT with the silicone phthalocyanine photosensitizer Pc 4 w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::490a636f5ab1cb010175ec9c0b1a3b0d
https://doi.org/10.3892/ijo.2013.2132
https://doi.org/10.3892/ijo.2013.2132