Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Tatyana I Merkulova"'
Autor:
Leonid O Bryzgalov, Elena V Antontseva, Marina Yu Matveeva, Alexander G Shilov, Elena V Kashina, Viatcheslav A Mordvinov, Tatyana I Merkulova
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e78833 (2013)
A vast amount of SNPs derived from genome-wide association studies are represented by non-coding ones, therefore exacerbating the need for effective identification of regulatory SNPs (rSNPs) among them. However, this task remains challenging since th
Externí odkaz:
https://doaj.org/article/eddd49633c714772a212d624cf6ca4cd
Publikováno v:
Vavilovskij Žurnal Genetiki i Selekcii, Vol 25, Iss 1, Pp 7-17 (2021)
Vavilov Journal of Genetics and Breeding
Vavilov Journal of Genetics and Breeding
The most popular model for the search of ChIP-seq data for transcription factor binding sites (TFBS) is the positional weight matrix (PWM). However, this model does not take into account dependencies between nucleotide occurrences in different site p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd7964c248b108117ede7809f45e5c29
https://doi.org/10.18699/vj21.002
https://doi.org/10.18699/vj21.002
Autor:
Polina E. Kisaretova, Vasiliy V. Reshetnikov, Tatyana I. Merkulova, Natalya P. Bondar, Nikita I. Ershov
Publikováno v:
Data in Brief, Vol 33, Iss, Pp 106365-(2020)
Data in Brief
Data in Brief
H3K4me3 is typically found in the promoter region of genes and is a mark associated with an open chromatin state and active gene transcription. Nonetheless, the role of H3K4me3 in the regulation of transcription is still debated. To improve the under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::321497aca9fe220245c4c1e17a84f863
http://www.sciencedirect.com/science/article/pii/S2352340920312580
http://www.sciencedirect.com/science/article/pii/S2352340920312580
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 17
International Journal of Molecular Sciences, Vol 21, Iss 6023, p 6023 (2020)
Volume 21
Issue 17
International Journal of Molecular Sciences, Vol 21, Iss 6023, p 6023 (2020)
(1) Background: Transcription factors (TFs) are main regulators of eukaryotic gene expression. The cooperative binding to genomic DNA of at least two TFs is the widespread mechanism of transcription regulation. Cooperating TFs can be revealed through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb016479ee8db5738fab9ecfd05a39d8
Background: Transcription factors (TFs) are main regulators of eukaryotic gene expression. The cooperative binding to genomic DNA of at least two TFs is the widespread mechanism of transcription regulation. Cooperating TFs can be revealed through the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e46b2b27c5419129759b4412f1a97050
https://doi.org/10.20944/preprints202007.0639.v1
https://doi.org/10.20944/preprints202007.0639.v1
Autor:
Polina E. Kisaretova, N. P. Bondar, Tatyana I. Merkulova, Vasiliy V. Reshetnikov, Nikita I. Ershov
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 106
Chronic stress is the leading risk factor of a broad range of severe psychopathologies. Nonetheless, the molecular mechanisms triggering these pathological processes are not well understood. In our study, we investigated the effects of 15-day social
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb5d036ac336d4c8688b6b3c342fbac1
https://pubmed.ncbi.nlm.nih.gov/32810572
https://pubmed.ncbi.nlm.nih.gov/32810572
Autor:
Arina O. Degtyareva, Elena E. Korbolina, Ilja I. Brusentsov, Elena Yu Leberfarb, Tatyana I. Merkulova, L. O. Bryzgalov
Publikováno v:
Human Mutation. 39:851-859
In the majority of colorectal cancer (CRC) cases, the genetic basis of predisposition remains unexplained. The goal of the study was to assess the regulatory SNPs (rSNPs) in the human genome and to reveal СRC drivers based on the available chromatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79a54c4c25979ba831fd323a33723997
https://doi.org/10.1002/humu.23425
https://doi.org/10.1002/humu.23425
Autor:
A. A. Studenikina, N. P. Bondar, J.A. Ryabushkina, Vasiliy V. Reshetnikov, Tatyana I. Merkulova
Publikováno v:
Behaviour. 155:181-203
Early life is an important period for the development of the nervous system and for the programming of behavioural phenotypes in adulthood. In our study, two types of early-life stress were used: prolonged separation of pups from their mothers (for 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d71a470c1f7e50a654f8f2aa0abd607
https://doi.org/10.1163/1568539x-00003482
https://doi.org/10.1163/1568539x-00003482
Publikováno v:
Biochemistry (Moscow). 82:351-365
Exposure to stress activates the hypothalamic-pituitary-adrenal axis and leads to increased levels of glucocorticoid (GC) hormones. Prolonged elevation of GC levels causes neuronal dysfunction, decreases the density of synapses, and impairs neuronal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::609d7ce75d17cd229e81e3326f0a8808
https://doi.org/10.1134/s0006297917030142
https://doi.org/10.1134/s0006297917030142
Publikováno v:
Vavilovskij Žurnal Genetiki i Selekcii, Vol 20, Iss 6, Pp 762-769 (2017)
On the basis of available data of ChIP-seq and ChIPchip experiments performed using antibodies against GAGA and CNC transcription factors, genome-wide binding mapping of these factors at hours 0–12 and 16–24 of Drosophila embryogenesis, as well a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0df2a66fb649b32817902030c54f8fc
https://vavilov.elpub.ru/jour/article/view/849
https://vavilov.elpub.ru/jour/article/view/849