Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Tatyana G. Kahn"'
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 11, Pp 3801-3812 (2019)
Antagonistic functions of Polycomb and Trithorax proteins are essential for proper development of all metazoans. While the Polycomb proteins maintain the repressed state of many key developmental genes, the Trithorax proteins ensure that these genes
Externí odkaz:
https://doaj.org/article/3569fbd5cec24931aed71bb5c9223888
Development of multicellular animals requires epigenetic repression by Polycomb group proteins. The latter assemble in multi-subunit complexes, of which two kinds, Polycomb Repressive Complex 1 (PRC1) and Polycomb Repressive Complex 2 (PRC2), act tog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6db0eaf97a64dfedf2fa8c2adc6affa
https://doi.org/10.1101/2023.01.12.523763
https://doi.org/10.1101/2023.01.12.523763
Autor:
Tatyana G. Kahn, Mikhail Savitsky, Chikuan Kuong, Caroline Jacquier, Giacomo Cavalli, Jia-Ming Chang, Yuri B. Schwartz
Drosophila insulators were the first DNA elements found to regulate gene expression by delimiting chromatin contacts. We still do not know how many of them exist and what impact they have on the Drosophila genome folding. Contrary to vertebrates, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8805abe315c9056bdff3781b7069084
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-204742
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-204742
Autor:
Tatyana G. Kahn, Mikhail Savitsky, Chikuan Kuong, Caroline Jacquer, Giacomo Cavalli, Jia-Ming Chang, Yuri B. Schwartz
Drosophila insulators were the first DNA elements discovered to regulate gene expression by delimiting chromatin contacts. Remarkably, it is still unclear how many of them exist in the Drosophila genome and whether they have a pervasive impact on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba9b8f03725e2a816568564151252ab5
https://doi.org/10.1101/2022.07.18.500462
https://doi.org/10.1101/2022.07.18.500462
Publikováno v:
PLoS Genetics, Vol 10, Iss 7, p e1004495 (2014)
Polycomb Group (PcG) proteins are epigenetic repressors that control metazoan development and cell differentiation. In Drosophila, PcG proteins form five distinct complexes targeted to genes by Polycomb Response Elements (PREs). Of all PcG complexes
Externí odkaz:
https://doaj.org/article/c79d9a1be2534a3db2c5ad899bdbe10b
Autor:
Tatyana G. Kahn, Juan I. Barrasa, Sarina R Cameron, Yuri B. Schwartz, Soumyadeep Nandi, Per Stenberg
Publikováno v:
Journal of Biological Chemistry. 293:14342-14358
Polycomb group proteins are essential epigenetic repressors. They form multiple protein complexes of which two kinds, PRC1 and PRC2, are indispensable for repression. Although much is known about their biochemical properties, how mammalian PRC1 and P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6208ca81421f653b3d8995efe633ddaf
https://doi.org/10.1074/jbc.ra118.005010
https://doi.org/10.1074/jbc.ra118.005010
Autor:
Yuri B Schwartz, Tatyana G Kahn, Per Stenberg, Katsuhito Ohno, Richard Bourgon, Vincenzo Pirrotta
Publikováno v:
PLoS Genetics, Vol 6, Iss 1, p e1000805 (2010)
Polycomb (PcG) regulation has been thought to produce stable long-term gene silencing. Genomic analyses in Drosophila and mammals, however, have shown that it targets many genes, which can switch state during development. Genetic evidence indicates t
Externí odkaz:
https://doaj.org/article/4f8d22b8028d49d69d1c2048091b9280
Autor:
Cheri A Schaaf, Ziva Misulovin, Gurmukh Sahota, Akbar M Siddiqui, Yuri B Schwartz, Tatyana G Kahn, Vincenzo Pirrotta, Maria Gause, Dale Dorsett
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6202 (2009)
The cohesin protein complex was first recognized for holding sister chromatids together and ensuring proper chromosome segregation. Cohesin also regulates gene expression, but the mechanisms are unknown. Cohesin associates preferentially with active
Externí odkaz:
https://doaj.org/article/199cb84bcf8944dbb1f2cbbd80bbbd81
Publikováno v:
Nucleus. 8:496-505
Polycomb Group (PcG) proteins epigenetically repress key developmental genes and thereby control alternative cell fates. PcG proteins act as complexes that can modify histones and these histone modifications play a role in transmitting the memory of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f5f8eabd2947dd4b1a9ed05ee62a722
https://doi.org/10.1080/19491034.2017.1363136
https://doi.org/10.1080/19491034.2017.1363136
Publikováno v:
G3: Genes|Genomes|Genetics
G3: Genes, Genomes, Genetics, Vol 9, Iss 11, Pp 3801-3812 (2019)
G3: Genes, Genomes, Genetics, Vol 9, Iss 11, Pp 3801-3812 (2019)
Antagonistic functions of Polycomb and Trithorax proteins are essential for proper development of all metazoans. While the Polycomb proteins maintain the repressed state of key developmental genes, the Trithorax proteins ensure that these genes stay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1116ea4c07b600c7dbccb5f7ed89058c
https://doi.org/10.1101/675173
https://doi.org/10.1101/675173