Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Tatyana Dvorkin"'
1
Effects of micro-environment- and malignant cell-derived interleukin-1 in carcinogenesis, tumour invasiveness and tumour–host interactions
Autor: Elena Voronov, Shraga Segal, Shahar Dotan, Ron N. Apte, Roslayn M. White, Xiaoping Song, Tatyana Dvorkin, Yakov Krelin, Lubov Gayvoronsky, Moshe Elkabets, Yaron Carmi, Eli Recih
Publikováno v: European Journal of Cancer. 42:751-759
Interleukin-1 (IL-1) comprises a family of closely related genes; the two major agonistic proteins, IL-1alpha and IL-1beta, are pleiotropic and affect mainly inflammation, immunity and haemopoiesis. IL-1beta is active solely in its secreted form, whe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::722a9e459d43d6db58823f3a8f8a356d
https://doi.org/10.1016/j.ejca.2006.01.010
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3
Immune phenomena involved in the in vivo regression of fibrosarcoma cells expressing cell-associated IL-1alpha
Autor: Margot Zöller, Ron N. Apte, Xiaoping Song, Tatyana Dvorkin, Elena Voronov, Shmuel Argov, Shraga Segal, Rosalyn M. White, Charles A. Dinarello
Publikováno v: Journal of leukocyte biology. 80(1)
Constitutive expression of cell-associated, but not secreted, interleukin-1α (IL-1α) by oncogene-transformed fibrosarcoma cells induced regressing tumors in mice, a phenomenon that was abrogated by the IL-1 inhibitor, the IL-1 receptor antagonist (
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74222ca8abef8151cf8f2e6e059bc4f7
https://pubmed.ncbi.nlm.nih.gov/16707560
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4
CD11b+/Gr-1+ immature myeloid cells mediate suppression of T cells in mice bearing tumors of IL-1beta-secreting cells
Autor: Elena Voronov, Ron N. Apte, Shraga Segal, Xiaoping Song, Yakov Krelin, Tatyana Dvorkin, Olle Bjorkdahl, Charles A. Dinarello
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 175(12)
Tumor cells secreting IL-1β are invasive and metastatic, more than the parental line or control mock-transfected cells, and concomitantly induce in mice general immune suppression of T cell responses. Suppression strongly correlates with accumulatio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13d9b0dee9f82b7fa539d64c96f22dba
https://pubmed.ncbi.nlm.nih.gov/16339559
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5
Self HSP60 peptide serves as an immunogenic carrier for a CTL epitope against persistence of murine cytomegalovirus in the salivary gland
Autor: Hila Amir-Kroll, Angel Porgador, Tatyana Dvorkin, Bracha Rager-Zisman, Ory Rouvio, Irun R. Cohen, Danit Atias
Publikováno v: Vaccine. 23(27)
Murine cytomegalovirus (MCMV) infection is associated with persistence of virus in the salivary glands, despite relatively rapid clearance of virus from the spleen. An effective immunization against MCMV should prevent such viral persistence. We prev
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5640e77a637d3085cd8b6ef75c909b50
https://pubmed.ncbi.nlm.nih.gov/15855009
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6
Cytokine-induced tumor immunogenicity: endogenous interleukin-1 alpha expressed by fibrosarcoma cells confers reduced tumorigenicity
Autor: Tatyana Dvorkin, Mahmoud Huleihel, Daniel Benharroch, Moshe Hacham, Elena Voronov, Noa Shimoni, Amos Douvdevani, Eyal Fima, Margot Zöller, Ron N. Apte, Shraga Segal, Rosalyn M. White
Publikováno v: Immunology letters. 39(1)
A direct correlation between the constitutive expression of IL-1α and reduced tumorigenicity of fibrosarcomas was observed. This was established in fibrosarcoma cell lines which produce IL-1α ‘spontaneously’, possibly as an aberration of oncoge
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2921e595411de35dda775bdffa887dd2
https://pubmed.ncbi.nlm.nih.gov/8144190
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