Human metapneumovirus driven IFN-β production antagonizes macrophage transcriptional induction of IL1-β in response to bacterial pathogens

Autor: Simon Loevenich, Nicola P. Montaldo, Arthur Wickenhagen, Tatyana Sherstova, Barbara van Loon, Victor Boyartchuk, Marit W. Anthonsen

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

Human metapneumovirus (HMPV) is a pneumovirus that may cause severe respiratory disease in humans. HMPV infection has been found to increase susceptibility to bacterial superinfections leading to increased morbidity and mortality. The molecular mecha

Externí odkaz: https://doaj.org/article/2f7c75507af942d99e8d201f9636c812

Cell-Type-Specific Transcription of Innate Immune Regulators in response to HMPV Infection

Autor: Marit W. Anthonsen, Tatyana Sherstova, Simon Loevenich, Youxian Li, Ann Magritt Liberg, Jostein Malmo, Ingvild Bjellmo Johnsen, Kristin Rian

Publikováno v: Mediators of Inflammation, Vol 2019 (2019)
Mediators of Inflammation

Human metapneumovirus (HMPV) may cause severe respiratory disease. The early innate immune response to viruses like HMPV is characterized by induction of antiviral interferons (IFNs) and proinflammatory immune mediators that are essential in shaping

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::607d4ef74bec949111bb37734b9a2920
https://doaj.org/article/c9887abd4159488092847f6daaae29ba

Hepatitis C virus triggers Golgi fragmentation and autophagy through the immunity-related GTPase M

Autor: Richard Kumaran Kandasamy, Gabriel Mary Richard, Eliane F. Meurs, Takaji Wakita, Marianne Doré Hansen, Ingvild Bjellmo Johnsen, Marit W. Anthonsen, Tatyana Sherstova, Kim Andre Ha Stiberg

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (17), pp.E3462-E3471. ⟨10.1073/pnas.1616683114⟩
E3462-E3471
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2017, 114 (17), pp.E3462-E3471. ⟨10.1073/pnas.1616683114⟩

Positive-stranded RNA viruses, such as hepatitis C virus (HCV), assemble their viral replication complexes by remodeling host intracellular membranes to a membranous web. The precise composition of these replication complexes and the detailed mechani

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c669dd6f9803dfe592c0dc3069167b61
https://hal-pasteur.archives-ouvertes.fr/pasteur-01507429

CD14, TLR4 and TRAM Show Different Trafficking Dynamics During LPS Stimulation

Autor: Dionne C G, Klein, Astrid, Skjesol, Esther D, Kers-Rebel, Tatyana, Sherstova, Bjørnar, Sporsheim, Kjartan W, Egeberg, Bjørn T, Stokke, Terje, Espevik, Harald, Husebye

Publikováno v: Traffic (Copenhagen, Denmark). 16(7)

Toll-like receptor 4 (TLR4) is responsible for the immediate response to Gram-negative bacteria and signals via two main pathways by recruitment of distinct pairs of adaptor proteins. Mal-MyD88 [Mal (MyD88-adaptor-like) - MYD88 (Myeloid differentiati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::546d4ccac3372816903ad6352acafe64
https://pubmed.ncbi.nlm.nih.gov/25707286